{"title":"Orthopedics","description":"","products":[{"product_id":"siringa-intra-articolare-preriempita-hymovis-hyadd4-esadecillamide-acido-ialuronico-24mg-3ml-2-pezzi-da-3-ml-non-sterilizzato-a-eto","title":"PRE-FILLED INTRA-ARTICULAR SYRINGE HYMOVIS HYADD4 HEXADECILLAMIDE HYALURONIC ACID 24MG\/3ML 2 PIECES OF 3ML NOT STERILIZED WITH ETO","description":"\u003ch1\u003e HYMOVIS\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Sterile hydrogel made with Hyadd4 (highly purified natural sodium hyaluronate hexadecylamide obtained from bacterial fermentation) in a buffered isotonic solution. Thanks to the high viscosity and elasticity provided by sodium hyaluronate hexadecylamide, HYMOVIS improves the lubricating and shock-absorbing properties of synovial fluid, protecting cartilage and soft tissue from mechanical injury. These properties, combined with its prolonged permanence in the joints, allow HYMOVIS to relieve pain and improve joint function for up to six months in mild to moderate osteoarthritis of the hip and knee.\u003cbr\u003e Indicated for the treatment of patients with mild to moderate osteoarthritis of the knee and hip. The device is indicated for the treatment of osteoarthritis of any nature. \u003cbr\u003eHYMOVIS is administered exclusively by intra-articular injection.\u003cbr\u003e The product must be administered exclusively by specialized medical personnel (e.g. orthopedic surgeon, rheumatologist, physiatrist, radiologist, sports doctor, etc.).\u003cbr\u003e Remove any joint effusion, if present, before administration. Inject intra-articularly only. Intra-articular injection must be performed according to the standard technique, with precise anatomical localization. In the hip, ultrasound or radioscopic guidance is recommended. Strictly follow all aseptic administration guidelines.\u003cbr\u003e Given its viscosity, inject HYMOVIS slowly into the joint using an appropriate sterile needle (18 or 20 G).\u003cbr\u003e Treatment consists of a single injection. No clinical data are available with more than one HYMOVIS injection.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Main component: Hyadd4 (sodium hyaluronate hexadecylamide), 32 mg\/4 ml. \u003cbr\u003eOther ingredients: sodium chloride, disodium hydrogen phosphate dodecahydrate, sodium dihydrogen phosphate dihydrate, water for injections.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e If there is venous or lymphatic stasis in the affected limb, HYMOVIS must not be injected into the joint.\u003cbr\u003e Do not administer to patients with known individual hypersensitivity to the components of the product or in case of infections or skin diseases in the injection area.\u003cbr\u003e Treatment should be avoided if the joint shows signs of acute inflammation.\u003cbr\u003e The safety and efficacy of using HYMOVIS with other intra-articular treatments have not been established.\u003cbr\u003e For the first 48 hours after the injection, the patient can perform all routine daily activities, but it is recommended not to overload the treated joint. \u003cbr\u003eThe syringe is for single use only; inject the contents into one joint only. The assembled syringe must be discarded immediately after use, regardless of whether the hydrogel has been completely administered.\u003cbr\u003e If the product is reprocessed and\/or reused, Fidia Farmaceutici cannot guarantee its performance, functionality, material structure, cleanliness, or sterility. Reuse may lead to illness, infection, and\/or serious harm to the patient or user.\u003cbr\u003e Do not use HYMOVIS after the expiration date printed on the carton. The expiration date refers to the product when stored properly in its original packaging.\u003cbr\u003e Do not use HYMOVIS if the package is open or damaged.\u003cbr\u003e Keep out of reach of children.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store in the original packaging between 2°C and 25°C. Do not freeze.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Case containing 1 pre-filled luer lock syringe.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e 10001310\u003c\/div\u003e","brand":"FIDIA FARMACEUTICI SPA","offers":[{"title":"Default Title","offer_id":50734365638990,"sku":"989259015","price":300.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/989259015-1.jpg?v=1776248540"},{"product_id":"cetilar-patch-cerotto-5pz","title":"SINGLE USE CETILAR PATCH PLASTER FOR JOINTS MUSCLES AND TENDONS 5 PIECES","description":"\u003ch1\u003e Cetilar Patch\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e \u003cbr\u003eLocally acting patch for muscle and joint health. Thanks to its patented formulation based on cetylated esters (CFA), Cetilar Patch helps restore range of motion and joint function, as well as reduce pain in cases of trauma, bruises, strains, contractures, and sprains. The patches adhere perfectly to the skin and do not cause irritation. Their slow-release action allows the cetylated esters to act on the affected area over a period of 8 hours, providing a lasting sensation of relief. Cetilar Patch also has an emollient effect thanks to the lipidic nature of its formulation. Furthermore, the presence of menthol gives the product a fresh, pleasant scent.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e Apply the patches to clean, dry skin and leave them on for at least 8 hours. If necessary, the application can be repeated throughout the day. \u003cbr\u003eIt is recommended to let the skin breathe for a short period between applications, in order to prevent sensitization or skin irritation, especially in the case of sensitive skin or on particularly delicate areas of the body.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Cetylated fatty acids (CFA).\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e For external use only. Do not ingest. Apply only to intact skin. Avoid contact with eyes and mouth. If contact occurs, rinse thoroughly with water. Do not use if you have a known hypersensitivity to any of the ingredients. If you are pregnant or breastfeeding, consult your doctor before using this product. If you are using this product on children under 12, consult your doctor before using this product.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store in a cool, dry place, between 5°C and 40°C, away from sunlight.\u003cbr\u003e Shelf life in intact packaging: 36 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack of 5 pieces.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e PH50\u003c\/div\u003e","brand":"PHARMANUTRA SPA","offers":[{"title":"Default Title","offer_id":50734391624014,"sku":"944898143","price":18.28,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/944898143.jpg?v=1768760829"},{"product_id":"cetilar-tape-striscia-ades-ane","title":"INELASTIC ADHESIVE STRIP CETILAR TAPE CM 4 X 2.5 M","description":"\u003ch1\u003e Cetilar Tape\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e \u003cbr\u003eCetilar is an inelastic adhesive strip that, thanks to its formulation based on plant-based cetyl esters (CFA), is indicated for the treatment of osteoarthritic joint conditions, improving joint function and range of motion, and reducing pain. It rapidly reduces joint and musculoskeletal pain; it is useful for regaining mobility during rehabilitation following inflammation or joint trauma; and it can be useful for recovering natural joint motion after sports injuries.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e Open the package and remove the strip. Cut the strip to size as needed. Make sure the skin is clean and dry before application. Apply, applying light pressure to ensure the edges adhere well to the skin. Leave it in place for 8 hours. Return the product to the package. \u003cbr\u003eThe application can be repeated throughout the day, allowing the skin to air out briefly between applications to prevent any potential sensitization. The adhesive strip used is disposable and not reusable.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Cetylated fatty acids of vegetable origin, acrylate copolymer, menthol.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e Keep out of the reach and sight of children. For external use only.\u003cbr\u003e The product should only be applied to intact, clean and dry skin.\u003cbr\u003e Avoid contact with mucous membranes, eyes and mouth. If contact occurs, rinse thoroughly with water.\u003cbr\u003e Remove the adhesive strip during bath\/shower.\u003cbr\u003e Discontinue treatment in case of evident irritation or hypersensitivity to the product.\u003cbr\u003e Do not use in case of known hypersensitivity to the components.\u003cbr\u003e Do not ingest. Do not use if packaging is damaged.\u003cbr\u003e Do not use after the expiration date. \u003cbr\u003eDo not use Cetilar Tape at the same time as other topical treatments used on the area to be treated, without consulting your doctor.\u003cbr\u003e If you are pregnant or breastfeeding, consult your doctor before using this product.\u003cbr\u003e In children under 12 years of age, consult a doctor before using the product.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store in a cool, dry place, between 5°C and 40°C.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack containing a 4 cm x 2.5 m inelastic adhesive strip.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e PH51\u003c\/div\u003e","brand":"PHARMANUTRA SPA","offers":[{"title":"Default Title","offer_id":50734391722318,"sku":"944898105","price":20.83,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-227546.jpg?v=1768760831"},{"product_id":"cingal-siringa-preriemp-4ml","title":"PRE-FILLED INTRA-ARTICULAR SYRINGE CINGAL 4 ML 22MG\/ML CROSS-LINKED ACID WITH 4.5 MG\/ML TRIAMCINOLONE HEXACETONIDE","description":"\u003cfont size=\"7\"\u003e\u003cb\u003e\u003ci\u003eC1 \u003csup\u003e+\u003c\/sup\u003e NGAL\u003c\/i\u003e\u003c\/b\u003e\u003c\/font\u003e\u003cbr\u003e\u003cbr\u003e \u003cfont size=\"2\"\u003eCROSS-LINKED SODIUM HYALURONATE 88 m2\u003cbr\u003e WITH TRIAMCINOLONE HEXACETONIDE 18 m2\u003cbr\u003e FOR INTRA-ARTICULAR INJECTION\u003c\/font\u003e\u003cbr\u003e\u003cbr\u003e\u003cdiv align=\"justify\"\u003e\n\n \u003cb\u003eMaterials\u003c\/b\u003e\u003cbr\u003e Cingal is a whitish, opaque, sterile, single-use suspension of a cross-linked hyaluronic acid (HA) gel with the addition of a corticosteroid (triamcinolone hexacetonide).\u003cbr\u003e\u003cbr\u003e \u003cb\u003ePresentation\u003c\/b\u003e\u003cbr\u003e HA is an essential component of the extracellular matrix and is found in high concentrations in the synovial fluid of joints.\u003cbr\u003e Hyaluronic acid is naturally biocompatible and its degradation process follows a normal physiological pathway.\u003cbr\u003e HA is responsible for the viscoelastic properties of synovial fluid.  \u003cbr\u003eSynovial fluid from joints affected by osteoarthritis has a lower HA concentration and a lower HA molecular weight than that of healthy joints. Sodium hyaluronate supplements (viscosupplements) have been shown to be well tolerated in synovial joints affected by osteoarthritis and work to reduce pain and improve function through lubrication and mechanical support.\u003cbr\u003e The added corticosteroid triamcinolone hexacetonide has an anti-inflammatory action to provide short-term pain relief when used as an intra-articular injection into a joint affected by osteoarthritis.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eSterility\u003c\/b\u003e\u003cbr\u003e Sterile product (steam sterilization).\u003cbr\u003e\u003cbr\u003e \u003cb\u003eValidity\u003c\/b\u003e\u003cbr\u003e 36 months (from date of manufacture).\u003cbr\u003e\u003cbr\u003e \u003cb\u003eClassification\u003c\/b\u003e\u003cbr\u003e Class III Medical Device (Directive 93-42-EEC).\u003cbr\u003e\u003cbr\u003e \u003cb\u003eRegulatory status\u003c\/b\u003e\u003cbr\u003e CE Marking (Designated Body 0120).\u003cbr\u003e  \u003cbr\u003eCingal is indicated as a viscoelastic supplement or as a substitute for synovial fluid in human joints.\u003cbr\u003e Cingal is suitable for the rapid and long-term relief of symptoms of joint diseases such as osteoarthritis.\u003cbr\u003e Cingal provides long-term symptom relief through lubrication and mechanical support, while also providing short-term pain relief thanks to triamcinolone hexacetonide.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eContraindications\u003c\/b\u003e\u003cbr\u003e Cingal is composed of cross-linked hyaluronic acid, triamcinolone hexacetonide, and inactive ingredients. The following pre-existing conditions may cause relative or absolute contraindications to the use of Cingal:\u003cbr\u003e • hypersensitivity to the active substance or to one of the excipients contained in Cingal;\u003cbr\u003e • pre-existing infections in the skin area of ​​the intended injection site;\u003cbr\u003e • known infection in the reference joint;\u003cbr\u003e • known systemic coagulation disorders. \u003cbr\u003eTriamcinolone hexacetonide, the ancillary medicinal substance, is contraindicated in cases of:\u003cbr\u003e • active tuberculosis;\u003cbr\u003e • herpes simplex keratitis;\u003cbr\u003e • acute psychosis;\u003cbr\u003e • systemic mycoses and parasitic infections (strongyloides infections).\u003cbr\u003e\u003cbr\u003e \u003cb\u003eInstructions for use\u003c\/b\u003e\u003cbr\u003e Cingal is injected directly into the chosen joint space using a sterile, disposable hypodermic needle of appropriate thickness.\u003cbr\u003e Healthcare personnel must insert the sterile needle into the Cingal syringe using an aseptic technique approved by the healthcare center.\u003cbr\u003e The recommended needle size for knee injections is 18-21 gauge.\u003cbr\u003e The final choice of needle for any procedure is the responsibility of the doctor.\u003cbr\u003e The doctor must ensure that the needle has entered the synovial space of the joint correctly before injecting Cingal.\u003cbr\u003e\u003cbr\u003e \u003cb\u003ePresentations\u003c\/b\u003e\u003cbr\u003e Cingal is a sterile preparation supplied in a 4.0 ml disposable glass syringe.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eStorage methods\u003c\/b\u003e \u003cbr\u003eStore at a temperature between 2 and 25°C.\u003cbr\u003e Avoid freezing.\u003cbr\u003e Before using Cingal, the refrigerated product must be brought to room temperature (this process takes approximately 20 to 45 minutes).\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e VRCN1\u003c\/div\u003e","brand":"ABIOGEN PHARMA SPA","offers":[{"title":"Default Title","offer_id":50734396178766,"sku":"971279601","price":180.5,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-140034_f8e5ef87-511c-47e2-b07e-fb12bca18a19.jpg?v=1768760867"},{"product_id":"hyadrol-siringa-intra-art-2ml","title":"INTRA-ARTICULAR SYRINGE HYADROL WITH HYALURONIC ACID 1% AND ADELMITROL 2% CAPACITY 2 ML","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e HYDROLYZER\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e\n\n \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e HYADROL is a class III medical device, sterile, single-use for intra-articular infiltration. It appears as a colorless, viscous and transparent liquid with a neutral pH (6.5\/7.5). It is made up of hyaluronic acid (1%) and adelmidrol (2%). The device does not contain human blood derivatives. It does not contain or incorporate tissues or substances of animal origin or derivatives. The device does not incorporate, as an integral part, medicinal substances. It is a device intended to promote the optimization of the natural viscoelastic lubrication process supported by hyaluronic acid in the treatment of metabolic disorders at the level of the joint capsule associated with degenerative atrophy.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Water for injections, adelmidrol, sodium hyaluronate, sodium chloride, potassium phosphate monobasic dihydrate, disodium EDTA, sodium hydrate.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e \u003cbr\u003e1 intra-articular infiltration every 7 days for 5 weeks, unless otherwise advised by your doctor. Use a sterile needle of appropriate size (from 18 G to 27 G). HYADROL can only be administered by qualified medical personnel, in adequate environmental conditions and observing the technical standards provided for intra-articular infiltration.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e \u003cbr\u003eParticular attention must be paid to patients with active infections in areas close to the one to be infiltrated, in order to avoid the onset of bacterial arthritis. In case of acute inflammation with abundant intra-articular effusion, it is advisable to reduce the effusion by evacuative arthrocentesis and, at the same time, proceed with the intra-articular injection of HYADROL. It is recommended not to subject the joint to excessive loads in the hours immediately following the infiltration. Do not sterilize again, do not reuse unused portions of solution, do not use if the package is open or damaged as the sterility of the product could be compromised. Reusing the device could entail risks of microbiological contamination of the patient. The product is not indicated for subjects already sensitized to the components present in the formulation. Discontinue treatment in the event of the onset of any undesirable effect. Keep out of the reach of children. Do not use after the expiry date. No teratogenic phenomena are known. In any case, it is recommended not to use the device during pregnancy and breastfeeding, unless otherwise advised by your doctor.\u003cbr\u003e \u003cbr\u003e\u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store the product in a cool, dry place at room temperature.\u003cbr\u003e Validity with intact packaging: 36 months.\u003cbr\u003e Check the expiration date indicated on the package and on the product. The expiration date indicated on the package refers to the product in intact packaging and correctly stored.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Sterile single-use pre-filled syringe containing 2 ml of HYADROL.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCode\u003c\/b\u003e 6301\u003c\/div\u003e","brand":"EPITECH GROUP SPA","offers":[{"title":"Default Title","offer_id":50734433304910,"sku":"983321276","price":64.6,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-244017.jpg?v=1768761490"},{"product_id":"hyalotend-1-sir-20mg-2ml","title":"INTRA-ARTICULAR SYRINGE HYALOTEND 20MG\/2ML 1 PIECE","description":"\u003ch1\u003e HYALOTEND\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e\n\n \u003cb\u003eDescription\u003c\/b\u003e \u003cbr\u003ePre-filled syringe with hyaluronic acid sodium salt solution for peritendinous use. Hyalotend is a viscous solution of hyaluronic acid sodium salt (500-730 kDa) obtained by bacterial fermentation, in buffered saline, for peritendinous injection. The solution (20 mg\/2 ml) is contained in a pre-filled syringe and is supplied sterile. Hyaluronic acid is a major component of synovial fluid, is produced in the normal tendon sheath, and is a major component of the tendon's extracellular matrix. The administration of exogenous hyaluronic acid sodium salt into the peritendinous space, thanks to its viscoelastic properties, reduces surface friction of the tendons, increases sliding capacity, reduces pain, and improves tendon function in tendinopathy, thus accelerating the return to normal activities and sports. Hyalotend is indicated for the treatment of pain and improvement of tendon elasticity in tendinopathy of the upper and lower limbs.\u003cbr\u003e \u003cbr\u003e\u003cb\u003eComposition\u003c\/b\u003e\u003cbr\u003e Hyaluronic acid sodium salt, sodium chloride, dibasic sodium phosphate dodecahydrate, monobasic sodium phosphate dihydrate, water for injections.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e The product should be administered only by experienced medical personnel. Use an ultrasound probe to guide the injection, if necessary. All rules regarding aseptic administration technique must be strictly followed. Do not use concomitantly with disinfectants containing quaternary ammonium salts, as hyaluronic acid may precipitate in their presence. Use a suitable sterile needle (21-25 G) according to medical advice. Discard the syringe and needle after single use. \u003cbr\u003eAdminister 3 peritendin injections of the product at weekly intervals, as directed by your doctor. If necessary, multiple tendons can be treated simultaneously. Each syringe is intended for injecting a single tendon. Repeated treatments may be performed if necessary.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e \u003cbr\u003eHyalotend should not be administered to patients with known hypersensitivity to any component of the product. Hyalotend peritend injections are contraindicated in cases of infection or skin disease at the injection site. Hyalotend has not been tested on pregnant women or individuals under 18 years of age and is therefore contraindicated in these patient populations. Do not use the product after the expiration date printed on the package. Do not use the product if the package is opened or damaged: the sterility of the solution is guaranteed as long as the package is closed and intact. The syringe is single-use, meaning it should be used for a single injection only. The assembled syringe must be discarded immediately after use, regardless of whether the solution has been completely administered or not. If a syringe is used for a subsequent injection, there is a risk of contamination that could lead to illness, infection, and\/or serious harm to the patient. If the product is reprocessed and\/or reused, Fidia Farmaceutici cannot guarantee its performance, functionality, material structure, cleanliness, or sterility. Reprocessing and\/or reuse may cause serious harm to patient health and safety. Dispose of the product after use in accordance with current regulations. As with any invasive joint procedure, care should be taken not to overload the joint immediately after peritendinous injection. Keep out of reach of children. Local reactions such as pain and heat or redness\/swelling\/bruising at the injection site may occur. These symptoms are usually transient and disappear spontaneously within a few days with rest and local ice application. Local or systemic allergic reactions due to individual hypersensitivity have been reported sporadically after hyaluronic acid injections.\u003cbr\u003e \u003cbr\u003e\u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e The product should be stored at a temperature not exceeding 25°C in the original packaging, protected from light. Do not freeze.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Carton containing 1 pre-filled syringe sealed in a blister.\u003cbr\u003e Box containing 3 pre-filled syringes, each sealed in a blister.\u003cbr\u003e The 20 mg\/2 ml solution of hyaluronic acid sodium salt contained in the pre-filled syringe is sterilized with steam.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e 10000122, 10000123\u003c\/div\u003e","brand":"FIDIA FARMACEUTICI SPA","offers":[{"title":"Default Title","offer_id":50734433829198,"sku":"980185728","price":42.75,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-212457.jpg?v=1768761498"},{"product_id":"hyalubrix-sir-30mg-2ml-n-e","title":"INTRA-ARTICULAR SYRINGE HYALUBRIX HYALURONIC ACID 1.5% 30 MG 2 ML NO ETO","description":"\u003ch1\u003e HYALUBRIX\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e\n\n \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e HYALUBRIX is a sterile viscoelastic solution produced with hyaluronic acid sodium salt obtained by bacterial fermentation from a high molecular weight fraction. \u003cbr\u003eHyaluronic acid is naturally present in many human tissues, such as cartilage and synovial fluid. It is continuously secreted into the joint cavity and is the major component of synovial fluid, providing it with its characteristic viscosity and elasticity. These properties are essential for the fluid to perform its lubricating and shock-absorbing functions in normal joints, protecting cartilage and soft tissue from mechanical damage.\u003cbr\u003e In traumatic and degenerative joint diseases, the amount of hyaluronic acid decreases and the synovial fluid loses viscosity, causing impaired function and painful symptoms. Many studies indicate that intra-articular administration of hyaluronic acid can restore the viscoelastic properties of the synovial fluid. \u003cbr\u003eHYALUBRIX is a treatment for the temporary replacement of synovial fluid in patients with degenerative or mechanical joint disease, which causes an alteration in the functional performance of the synovial fluid. Intra-articular injection of HYALUBRIX at weekly intervals reduces pain symptoms and improves joint function in patients with degenerative or mechanical joint disease for up to six months.\u003cbr\u003e It is indicated for the treatment of pain and improvement of joint function in patients with degenerative or mechanical arthropathy of the knee, hip, shoulder, ankle, and trapeziometacarpal joint. The product is indicated for the treatment of persistent pain after initial analgesic failure or in cases of failure or intolerance to nonsteroidal anti-inflammatory drugs.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComposition\u003c\/b\u003e \u003cbr\u003eHyaluronic acid sodium salt 1.5%, sodium chloride, dibasic sodium phosphate 12H \u003csub\u003e2\u003c\/sub\u003e O, monobasic sodium phosphate 2H \u003csub\u003e2\u003c\/sub\u003e O, water for injections.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e The injection must be strictly intra-articular. Intra-articular injections must be performed according to standard technique, using a precise anatomical location. In the hip, shoulder, and other less easily accessible joints, ultrasound or radioscopic guidance is recommended.\u003cbr\u003e All rules regarding asepsis and injection techniques must be observed.\u003cbr\u003e Remove any joint effusions, if present, prior to administration.\u003cbr\u003e Inject HYALUBRIX using a suitable sterile needle (e.g. 18 or 20 G), into the affected joint at weekly intervals for 3 weeks. \u003cbr\u003eIf necessary, additional cycles of injections can be performed, although systematic collection of clinical data is not available. Clinical data demonstrate the efficacy of HYALUBRIX for up to 6 months, however, if clinically necessary, the administration cycle can be repeated starting 3 months after the first treatment cycle.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e \u003cbr\u003eDo not administer to patients with known individual sensitivity to the product components. Do not administer in case of infections or skin diseases in the injection area. Do not administer to patients with active synovitis. The safety and efficacy of HYALUBRIX in pregnant women, breastfeeding women, or individuals under 18 years of age have not been established and therefore its use is contraindicated in these patient populations. Do not use if the package is damaged. Do not use the product after the expiry date shown on the package. The expiry date refers to the product stored in its original packaging. The syringe is for single use only, meaning it is for single use only and on a single patient. Inject the contents into one joint only. For the first 24 hours after the injection, the patient is permitted to continue all routine daily activities, but it is recommended not to overload the treated joint. The syringe complete with needle must be discarded immediately after use, even if the solution has not been completely administered. If the product is reprocessed and\/or reused, Fidia Farmaceutici cannot guarantee its performance, functionality, material structure, cleanliness, or sterility. Reuse may lead to illness, infection, and\/or harm to the patient or user. Dispose of it according to applicable regulations after use. Keep out of reach of children. \u003cbr\u003eLocalized pain, swelling, heat, and redness may occasionally occur at the injection site. These symptoms are generally mild and transient. After intra-articular injection, applying an ice pack to the treated joint for five to ten minutes will reduce the incidence of these events. Local or systemic allergic reactions may occur in individuals with hypersensitivity to the product's components. More marked inflammatory reactions, sometimes with the presence of sodium pyrophosphate crystals, have occasionally been reported in association with intra-articular injections of hyaluronate. As with any intra-articular treatment, septic arthritis may rarely occur if general injection precautions are not observed or the injection site is not aseptic. \u003cbr\u003eDo not use concomitantly with disinfectants containing quaternary ammonium salts, as hyaluronic acid may precipitate in their presence. Avoid concomitant administration of HYALUBRIX with other products for intra-articular use to prevent any possible interactions.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store below 25°C.\u003cbr\u003e Shelf life in intact packaging: 24 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Case containing 1 pre-filled syringe.\u003cbr\u003e The syringe is sealed in an ethylene oxide sterilized blister and contains 30 mg of hyaluronic acid sodium salt in 2 ml of steam sterilized solution.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e 10000950\u003c\/div\u003e","brand":"FIDIA FARMACEUTICI SPA","offers":[{"title":"Default Title","offer_id":50734433927502,"sku":"984515458","price":48.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/984515458-1.jpg?v=1776905102"},{"product_id":"sinovial-hl-64-sir-intra-art","title":"INTRA-ARTICULAR SYRINGE SINOVIAL HL 64 HYALURONIC ACID SODIUM SALT 3.2% 32MG H-HA + 32MG H-LA\/2ML 2 ML","description":"\u003ch1\u003e SINOVIAL HL 64 2 ml\u003c\/h1\u003e\n\u003ch2\u003e 3.2% - 32 mg (H-HA) + 32 mg (L-HA)\/2 ml\u003c\/h2\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Visco-supplementary joint device.\u003cbr\u003e The sodium salt of hyaluronic acid is formed by repeating chains of disaccharide units of N-acetylglucosamine and sodium glucuronate and represents a fundamental component of the synovial fluid, to which it gives its particular viscoelastic properties. \u003cbr\u003eConsisting of a buffered physiological solution of high molecular weight (H-HA) and low molecular weight (L-HA) hyaluronic acid. The high and low molecular weight hyaluronic acid used in the device is obtained through fermentation and has not undergone chemical modification. This results in excellent tolerability. Furthermore, the HA chains with different molecular weights present in SINOVIAL HL 64 2 ml, thanks to a specific and patented treatment of the solution, interact with each other, giving SINOVIAL HL 64 2 ml unique rheological characteristics that allow for the administration of higher concentrations of hyaluronic acid with the same solution viscosity. The HA chains of different molecular weights in SINOVIAL HL 64 2 ml provide greater resistance to hyaluronidase since this enzyme is unable to recognize the conformation of these high and low molecular weight complexes, therefore, SINOVIAL HL 64 2 ml is more suitable for in vivo applications in tissues. \u003cbr\u003eIndicated in cases of acute and chronic tendinopathies and\/or those associated with joint disability and in the tendon repair process, even following surgery.\u003cbr\u003e Designed to supplement synovial fluid, restoring the physical and rheological properties of arthritic joints and tendons. In the joint, SINOVIAL HL 64 2 ml reduces pain and promotes recovery of associated joint and tendon mobility, acting only in the synovial cavity into which it is injected, without exerting any systemic action. \u003cbr\u003eThanks to its lubricating and viscoelastic properties, it acts on the tendon sheath, improving tendon gliding and the physiological healing\/repair processes, thus preventing the formation of adhesions in the post-operative period. Treatment may consist of up to three injections, depending on the severity of the joint and\/or tendon degeneration. The appropriateness and frequency of repeat treatment must be assessed by the physician for each individual patient, considering the risk\/benefit ratio of the treatment.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e Aspirate any joint effusion before injecting SINOVIAL HL 64 2 ml.\u003cbr\u003e Carefully unscrew the syringe cap, holding the “Luer Lock” collar firmly between your fingers and taking particular care to avoid contact with the opening.  \u003cbr\u003eInsert the needle into the Luer Lock closure collar of the syringe (18 or 22G diameter needle included in the package) and screw it firmly until you feel a light pressure, so as to ensure a watertight seal and prevent the liquid from leaking during administration, keeping the “Luer Lock” closure collar firmly between your fingers.\u003cbr\u003e Inject SINOVIAL HL 64 2 ml at room temperature and under conditions of strict aseptic conditions, into the synovial space of the joint or into the tendon sheath\/peritendinous area, depending on the identified medical need.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e High molecular weight hyaluronic acid (H-HA) and low molecular weight hyaluronic acid (L-HA), sodium chloride, sodium phosphate and water for injections.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e - The contents of the pre-filled syringe are sterile. The syringe and needle are packaged in a sealed blister.\u003cbr\u003e The outer surface of the syringe is not sterile. \u003cbr\u003e- Do not use SINOVIAL HL 64 2 ml after the expiry date.\u003cbr\u003e - Do not use SINOVIAL HL 64 2 ml if the packaging is open or damaged.\u003cbr\u003e - The injection site must be on healthy skin.\u003cbr\u003e - Do not inject intravascularly. Do not inject outside the joint cavity, into the synovial tissue, or into the joint capsule.\u003cbr\u003e - Do not administer SINOVIAL HL 64 2 ml in the presence of large intra-articular effusion.\u003cbr\u003e - Do not re-sterilize. The device is for single use only.\u003cbr\u003e - Do not reuse to avoid any risk of contamination.\u003cbr\u003e - Once opened, it must be used immediately and discarded after use.\u003cbr\u003e - Keep out of the reach and sight of children.\u003cbr\u003e - After the injection, advise the patient to avoid all strenuous physical activity and to resume normal activities only after a few days.\u003cbr\u003e - The possible presence of an air bubble does not affect the characteristics of the product. \u003cbr\u003e- DO NOT mix the product with disinfectants such as quaternary ammonium salts or chlorhexidine as a precipitate may form.\u003cbr\u003e - The product should not be injected if the joint is infected or severely inflamed or if the patient has a skin condition or infection at the injection site.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store at room temperature, below 25°C, away from heat sources. Do not freeze.\u003cbr\u003e Shelf life when packaging is intact: 36 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack of 1 pre-filled syringe of 2 ml [32 mg (H-HA) + 32 mg (L-HA) hyaluronic acid sodium salt in 2 ml of sodium chloride buffered saline solution] and 1 needle 21G x 1 ½\" (0.8 x 40 mm).\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e 6000001389\u003c\/div\u003e","brand":"IBSA FARMACEUTICI ITALIA SRL","offers":[{"title":"Default Title","offer_id":50734494384462,"sku":"982951459","price":134.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-240313.jpg?v=1768762263"},{"product_id":"supartz-sir-intra-art-2-5ml-1p","title":"SUPARTZ INTRA-ARTICULAR PRE-FILLED SYRINGE HYALURONIC ACID 25 MG 2.5 ML 1 PIECE","description":"\u003ch1\u003e SUPARTZ\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e\n\n \u003cb\u003eDescription\u003c\/b\u003e \u003cbr\u003eSUPARTZ is a sterile, non-pyrogenic, highly purified, non-inflammatory, high molecular weight sodium hyaluronate solution extracted by bacterial fermentation and is a polysaccharide containing repeating disaccharide units of D-glucuronic acid and N-acetyl-D-glucosamine.\u003cbr\u003e Sodium hyaluronate is a common component of the extracellular matrices of connective tissues. It is found in many different species, including humans, but is chemically identical regardless of its species of origin.\u003cbr\u003e The sodium hyaluronate used in the manufacture of SUPARTZ is of bacterial origin and is derived through fermentation and purification.\u003cbr\u003e SUPARTZ is a clear, odorless solution with a pH of 6.8 to 7.8 and an osmotic pressure to saline ratio of 1.0 to 1.2. \u003cbr\u003eAfter injection into the joint, SUPARTZ is poorly metabolized in the synovial fluid, but is incorporated into the synovial tissues where it is partially degraded into smaller molecules. SUPARTZ then enters the bloodstream and is metabolized primarily in the liver. The metabolites are non-toxic and are permanently eliminated from the body through the lungs, intestines, and urinary tract.\u003cbr\u003e SUPARTZ is marketed as a sterile solution in a pre-filled disposable syringe to reduce the risk of contamination during aspiration of the solution.\u003cbr\u003e SUPARTZ is indicated for the treatment of knee OA and shoulder periarthritis, and is intended to improve joint motion by supplementing the viscoelasticity of synovial fluid, and to reduce pain in knee OA and shoulder periarthritis.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e \u003cbr\u003eThe dosage is 2.5 mL (one syringe) per knee joint injected intra-articularly or into the shoulder joint (shoulder socket, subacromial bursa, or tendon sheath of the long head of the biceps brachii).\u003cbr\u003e The recommended treatment regimen for SUPARTZ in adults consists of five injections into the knee joint cavity or shoulder joint (joint cavity, subacromial bursa, or biceps tendon sheath), at intervals of one injection per week. However, the timing of injections may be adjusted based on the patient's symptoms.\u003cbr\u003e SUPARTZ must be injected only by authorised medical personnel or in accordance with local legislation.\u003cbr\u003e No additional training is required.\u003cbr\u003e Check the expiry date on the package.\u003cbr\u003e Do not use after the expiration date.\u003cbr\u003e Strictly observe aseptic administration techniques. \u003cbr\u003eAspirate any joint effusion using a 22-23 gauge needle before injecting SUPARTZ. Maintain the needle position in the joint while removing the syringe used to reduce the joint effusion. Discard the syringe containing the aspirated joint effusion. Do not use the same syringe to aspirate the effusion and inject SUPARTZ.\u003cbr\u003e Subcutaneous injection of lidocaine or similar local anaesthetics may be performed prior to injection of SUPARTZ.\u003cbr\u003e Peel the Tyvek sheet from the blister and remove the syringe.\u003cbr\u003e Carefully remove the syringe cap and aseptically attach the syringe to a 22-23G needle. To ensure a tight seal and prevent leaks during administration (or injection), secure the needle by holding the luer lock firmly.\u003cbr\u003e If the effusion has been previously aspirated, connect the syringe to the needle already placed in the joint. \u003cbr\u003eUnscrew the cap before removing it to minimize product spillage.\u003cbr\u003e Inject SUPARTZ into the knee joint or shoulder joint (shoulder socket, subacromial bursa, or tendon sheath of the long head of the biceps brachii) through the needle using an aseptic injection technique.\u003cbr\u003e Inject the entire contents, 2.5 mL of SUPARTZ, into the knee or shoulder (shoulder socket, subacromial bursa, or biceps tendon sheath). If administering to both knees or shoulders, use a separate syringe of SUPARTZ for each knee or shoulder.\u003cbr\u003e To inject into the knee joint, insert the needle horizontally or at a slight downward angle into the joint space between the kneecap and the femur. It's not unusual to feel some resistance as the needle enters the joint capsule. \u003cbr\u003eIn the scapulohumeral joint, the needle is usually inserted most easily from the anterior side, but a posterior or lateral approach is also used.\u003cbr\u003e For accurate administration of SUPARTZ into the biceps sheath, insert the needle into the epidermis at a 20-30 degree angle and parallel to the biceps sheath. If the needle penetrates the tendon, resistance to the injection will occur. If available, perform an ultrasound-guided injection into the biceps sheath to more accurately identify the location.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e 2.5 ml of 1% sodium hyaluronate solution.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e - Do not administer SUPARTZ to patients with known hypersensitivity (allergy) to SUPARTZ or sodium hyaluronate preparations.\u003cbr\u003e - Extreme caution should be exercised when administering SUPARTZ to patients with infections or skin lesions at the injection site.\u003cbr\u003e - Administer SUPARTZ with caution in patients with hypersensitivity to any medicinal product. \u003cbr\u003e- Administer SUPARTZ with caution in patients with a history of liver dysfunction.\u003cbr\u003e - Administer SUPARTZ with caution in patients with systemic coagulopathies.\u003cbr\u003e - Administer SUPARTZ with caution to patients with lymphatic or venous stasis in the injected limb.\u003cbr\u003e - Do not use disinfectants containing quaternary ammonium salts (such as benzalkonium chloride) for skin preparation simultaneously, as sodium hyaluronate may precipitate in their presence. The use of disinfectants such as povidone-iodine is recommended.\u003cbr\u003e - Do not inject SUPARTZ intravascularly.\u003cbr\u003e - Strictly observe aseptic administration techniques.\u003cbr\u003e - Aspirate any joint effusion before injecting SUPARTZ.\u003cbr\u003e - The safety and performance of SUPARTZ have not been established in joints other than the knee or shoulder and for diseases other than OA. \u003cbr\u003e- The safety and performance of SUPARTZ in combination with other intra-articular injectable solutions have not been established.\u003cbr\u003e - The safety and efficacy of SUPARTZ in severely inflamed knee joints have not been established.\u003cbr\u003e - Do not inject SUPARTZ extra-articularly or into the synovial membrane and capsule.\u003cbr\u003e - STERILE CONTENTS. The pre-filled syringe is for single use only. The contents of the syringe must be used immediately after opening the package. Discard any unused SUPARTZ.\u003cbr\u003e - Do not use SUPARTZ if the blister is open or damaged or if there are cracks or breaks in the pre-filled syringe.\u003cbr\u003e - In osteoarthritic knees with severe inflammation, the inflammation should be reduced before injecting SUPARTZ, as the inflammation may be aggravated by the injection.\u003cbr\u003e - Use SUPARTZ by the expiry date indicated on the package. \u003cbr\u003e- As with any invasive joint procedure, the patient is advised to avoid any strenuous activity (such as jogging, tennis or other active sports, heavy work) and prolonged weight-bearing activities (such as standing for more than one hour) for 48 hours following treatment with intra-articular injection of SUPARTZ.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e The expiry date is indicated on the label and on the outer packaging.\u003cbr\u003e Store in the original packaging at a temperature of 1°C-25°C.\u003cbr\u003e Don't conglate.\u003cbr\u003e Shelf life in intact packaging: 36 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e 1 pre-filled syringe 2.5 ml.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e MD030701\u003c\/div\u003e","brand":"MDM SPA","offers":[{"title":"Default Title","offer_id":50734499692878,"sku":"943008540","price":41.8,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-185753_a1467800-294e-4324-b895-218000bbbdb8.jpg?v=1768762354"},{"product_id":"supartz-sir-intra-art-2-5ml-3p","title":"PRE-FILLED INTRA-ARTICULAR SYRINGE SUPARTZ HYALURONIC ACID 25 MG 2.5 ML 3 PIECES","description":"\u003ch1\u003e Supartz\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e\n\n \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e SUPARTZ is a sterile, non-pyrogenic, highly purified, non-inflammatory, high molecular weight sodium hyaluronate solution extracted by bacterial fermentation and is a polysaccharide containing repeating disaccharide units of D-glucuronic acid and N-acetyl-D-glucosamine. \u003cbr\u003eSodium hyaluronate is a common component of the extracellular matrices of connective tissues. It is found in many different species, including humans, but is chemically identical regardless of its species of origin.\u003cbr\u003e The sodium hyaluronate used in the manufacture of SUPARTZ is of bacterial origin and is derived through fermentation and purification.\u003cbr\u003e SUPARTZ is a clear, odorless solution with a pH of 6.8 to 7.8 and an osmotic pressure to saline ratio of 1.0 to 1.2.\u003cbr\u003e After injection into the joint, SUPARTZ is poorly metabolized in the synovial fluid, but is incorporated into the synovial tissues where it is partially degraded into smaller molecules. SUPARTZ then enters the bloodstream and is metabolized primarily in the liver. The metabolites are non-toxic and are permanently eliminated from the body through the lungs, intestines, and urinary tract. \u003cbr\u003eSUPARTZ is marketed as a sterile solution in a pre-filled disposable syringe to reduce the risk of contamination during aspiration of the solution.\u003cbr\u003e SUPARTZ is indicated for the treatment of knee OA and shoulder periarthritis, and is intended to improve joint motion by supplementing the viscoelasticity of synovial fluid, and to reduce pain in knee OA and shoulder periarthritis.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e The dosage is 2.5 mL (one syringe) per knee joint injected intra-articularly or into the shoulder joint (shoulder socket, subacromial bursa, or tendon sheath of the long head of the biceps brachii). \u003cbr\u003eThe recommended treatment regimen for SUPARTZ in adults consists of five injections into the knee joint cavity or shoulder joint (joint cavity, subacromial bursa, or biceps tendon sheath), at intervals of one injection per week. However, the timing of injections may be adjusted based on the patient's symptoms.\u003cbr\u003e SUPARTZ must be injected only by authorised medical personnel or in accordance with local legislation.\u003cbr\u003e No additional training is required.\u003cbr\u003e Check the expiry date on the package.\u003cbr\u003e Do not use after the expiration date.\u003cbr\u003e Strictly observe aseptic administration techniques. \u003cbr\u003eAspirate any joint effusion using a 22-23 gauge needle before injecting SUPARTZ. Maintain the needle position in the joint while removing the syringe used to reduce the joint effusion. Discard the syringe containing the aspirated joint effusion. Do not use the same syringe to aspirate the effusion and inject SUPARTZ.\u003cbr\u003e Subcutaneous injection of lidocaine or similar local anaesthetics may be performed prior to injection of SUPARTZ.\u003cbr\u003e Peel the Tyvek sheet from the blister and remove the syringe.\u003cbr\u003e Carefully remove the syringe cap and aseptically attach the syringe to a 22-23G needle. To ensure a tight seal and prevent leaks during administration (or injection), secure the needle by holding the luer lock firmly.\u003cbr\u003e If the effusion has been previously aspirated, connect the syringe to the needle already placed in the joint. \u003cbr\u003eUnscrew the cap before removing it to minimize product spillage.\u003cbr\u003e Inject SUPARTZ into the knee joint or shoulder joint (shoulder socket, subacromial bursa, or tendon sheath of the long head of the biceps brachii) through the needle using an aseptic injection technique.\u003cbr\u003e Inject the entire contents, 2.5 mL of SUPARTZ, into the knee or shoulder (shoulder socket, subacromial bursa, or biceps tendon sheath). If administering to both knees or shoulders, use a separate syringe of SUPARTZ for each knee or shoulder.\u003cbr\u003e To inject into the knee joint, insert the needle horizontally or at a slight downward angle into the joint space between the kneecap and the femur. It's not unusual to feel some resistance as the needle enters the joint capsule. \u003cbr\u003eIn the scapulohumeral joint, the needle is usually inserted most easily from the anterior side, but a posterior or lateral approach is also used.\u003cbr\u003e For accurate administration of SUPARTZ into the biceps sheath, insert the needle into the epidermis at a 20-30 degree angle and parallel to the biceps sheath. If the needle penetrates the tendon, resistance to the injection will occur. If available, perform an ultrasound-guided injection into the biceps sheath to more accurately identify the location.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e 2.5 ml of 1% sodium hyaluronate solution.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e - Do not administer SUPARTZ to patients with known hypersensitivity (allergy) to SUPARTZ or sodium hyaluronate preparations.\u003cbr\u003e - Extreme caution should be exercised when administering SUPARTZ to patients with infections or skin lesions at the injection site.\u003cbr\u003e - Administer SUPARTZ with caution in patients with hypersensitivity to any medicinal product. \u003cbr\u003e- Administer SUPARTZ with caution in patients with a history of liver dysfunction.\u003cbr\u003e - Administer SUPARTZ with caution in patients with systemic coagulopathies.\u003cbr\u003e - Administer SUPARTZ with caution to patients with lymphatic or venous stasis in the injected limb.\u003cbr\u003e - Do not use disinfectants containing quaternary ammonium salts (such as benzalkonium chloride) for skin preparation simultaneously, as sodium hyaluronate may precipitate in their presence. The use of disinfectants such as povidone-iodine is recommended.\u003cbr\u003e - Do not inject SUPARTZ intravascularly.\u003cbr\u003e - Strictly observe aseptic administration techniques.\u003cbr\u003e - Aspirate any joint effusion before injecting SUPARTZ.\u003cbr\u003e - The safety and performance of SUPARTZ have not been established in joints other than the knee or shoulder and for diseases other than OA. \u003cbr\u003e- The safety and performance of SUPARTZ in combination with other intra-articular injectable solutions have not been established.\u003cbr\u003e - The safety and efficacy of SUPARTZ in severely inflamed knee joints have not been established.\u003cbr\u003e - Do not inject SUPARTZ extra-articularly or into the synovial membrane and capsule.\u003cbr\u003e - STERILE CONTENTS. The pre-filled syringe is for single use only. The contents of the syringe must be used immediately after opening the package. Discard any unused SUPARTZ.\u003cbr\u003e - Do not use SUPARTZ if the blister is open or damaged or if there are cracks or breaks in the pre-filled syringe.\u003cbr\u003e - In osteoarthritic knees with severe inflammation, the inflammation should be reduced before injecting SUPARTZ, as the inflammation may be aggravated by the injection.\u003cbr\u003e - Use SUPARTZ by the expiry date indicated on the package. \u003cbr\u003e- As with any invasive joint procedure, the patient is advised to avoid any strenuous activity (such as jogging, tennis or other active sports, heavy work) and prolonged weight-bearing activities (such as standing for more than one hour) for 48 hours following treatment with intra-articular injection of SUPARTZ.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e The expiry date is indicated on the label and on the outer packaging.\u003cbr\u003e Store in the original packaging at a temperature of 1°C-25°C.\u003cbr\u003e Don't conglate.\u003cbr\u003e Shelf life in intact packaging: 36 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e 3 pre-filled syringes 2.5 ml.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e MD030751\u003c\/div\u003e","brand":"MDM SPA","offers":[{"title":"Default Title","offer_id":50734499725646,"sku":"943008577","price":111.15,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-333928.jpg?v=1768762355"},{"product_id":"tendovis-sir-intra-art-1-2ml","title":"INTRA-ARTICULAR SYRINGE TENDOVIS HYALURONIC ACID 12MG 1.2ML TENDOVIS 1 PIECE","description":"\u003cp\u003e Tendovis Hyaluronic Acid Syringe Tendon Infiltrations 1% 1.2ml\u003c\/p\u003e\n\n\n \u003cp\u003eEndoVis is a sterile, clear solution of 1% sodium hyaluronate in phosphate buffered saline and contained in a ready-to-use pre-filled syringe suitable for periarticular injection into soft tissues surrounding tendons and ligaments. Sodium hyaluronate is a long polysaccharide chain composed of repeating disaccharide units, which are normally found in the human body.\u003c\/p\u003e\n\n\n\u003cp\u003e TendoVis has a pH and osmolarity that are biocompatible with soft tissue. 1.2 ml of TendoVis, sterilized by filtration, is contained in a disposable glass syringe, ready for use. The syringe is in turn contained in a blister, packaged in a cardboard box.\u003c\/p\u003e\n\n\n \u003cp\u003eAnkle Sprain: 1.2 ml of TendoVisTM should be injected preferably within 48 hours of the injury and the second 1.2 ml injection should be performed within 2-3 days of the first; a 27 G needle is recommended. Periarticular injections should be performed through a single needle insertion site along the talofibular ligament using anatomical landmarks. The injection should be performed following 3 planes: from the anteroposterior, median and lateral to the proximal ligament.\u003cbr\u003e\n\u003cbr\u003e\r \nLateral epicondylitis: One injection of 1.2 ml of TendoVisTM into the lateral epicondyle of the elbow, followed by an injection one week after the first; a 27 gauge needle is recommended. Identify the softest point of the epicondyle by gentle palpation. Position the needle at 45 degrees at the point of maximum tenderness in the lateral epicondyle. After insertion of the needle into the skin, position the needle parallel to the skin and insert it at the point of maximum tenderness in the lateral epicondyle. Inject half of the contents while withdrawing the needle, but without withdrawing it from the injection site. Rotate the needle 180 degrees (opposite direction) and insert the needle parallel to the skin towards the point of maximum tenderness in the lateral epicondyle. Inject the remaining contents while withdrawing the needle outward. Remove the needle from the skin insertion site. Flex and extend your elbow five times and then rotate it internally and externally five times. \u003cbr\u003e\n\u003cbr\u003e\nRotator cuff tendinopathy: One injection of 1.2 ml of TendoVisTM into the subacromial space of the shoulder just above the tendon, followed by a second injection 14 days later; a 22 gauge needle is recommended. Sit the patient upright, arm extended and externally rotated. Use of an ultrasound probe placed on the lateral side of the shoulder directed in the plane of the supraspinatus tendon is recommended to guide the injection. Locate the acromion, greater tubercle, humeral head and subacromial fissure. Insert the needle into the fissure 1 cm distal posterior and 2 cm to the lateral anterior-acromial border. Advance the needle horizontally and in a medial direction partly beneath the acromion process. When no resistance is felt from the plunger, inject TendoVisTM over the humeral head into the subacromial space taking care not to inject into the tendon.\u003c\/p\u003e\n\n\n \u003cp\u003eTendoVis is intended to relieve pain and optimize the recovery of tendons and ligaments damaged by acute or chronic injuries. TendoVis Sodium Hyaluronate augments the sodium hyaluronate naturally present in the soft tissue surrounding damaged tendons and ligaments and provides support, lubrication and hydration to the affected site thus providing the ideal environment for the healing of the damaged tissue. TendoVisTM has been shown to relieve pain and optimize the recovery of function in the ankle following first or second degree sprains, to relieve chronic pain and disability of the elbow with lateral epicondylalgia and to relieve pain in symptomatic patients with rotator cuff tendinopathy.\u003c\/p\u003e\n\n\n\u003cp\u003e Medical device\u003cbr\u003e\n Use only by specialized personnel\u003c\/p\u003e\n\n","brand":"MDT INT'L SA","offers":[{"title":"Default Title","offer_id":50734501953870,"sku":"925332494","price":75.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/925332494.jpg?v=1768762381"},{"product_id":"rudravisc-40-hc-sir-intra-art","title":"INTRA-ARTICULAR SYRINGE RUDRAVISC 40 HC HYALURONIC ACID SODIUM SALT 40 MG 2 ML 3 PIECES","description":"\u003cdiv\u003eRudravisc 40 sir 40mg 2ml 3pcs solution for injection\u003cbr\u003e\n\n\u003c\/div\u003e\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\u003cdiv\u003e Medical device\u003cbr\u003e\n\n\u003c\/div\u003e\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e Contains the active ingredients: hyaluronic acid sodium salt ","brand":"SHEDIR PHARMA SRL UNIPERSONALE","offers":[{"title":"Default Title","offer_id":50734557004110,"sku":"941869253","price":156.75,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/941869253.jpg?v=1768762896"},{"product_id":"condronil-ialdue-siringa-2ml","title":"CONDRONIL IALDUE PRE-FILLED INTRA-ARTICULAR SYRINGE HYALURONIC ACID SODIUM SALT 40 MG 2 ML","description":"\u003ch1\u003e CondronilIALDUE\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e CondronilIALDUE is a sterile, biodegradable, isotonic injectable gel for intra-articular use. CondronilIALDUE consists of a medium molecular weight hyaluronic acid (1.0–1.5 \/ 106 Daltons), produced by Streptococcus equi bacteria, formulated at a concentration of 20 mg\/ml in a physiological buffer. \u003cbr\u003eCondronilIALDUE is characterised by viscoelastic properties, therefore it helps to normalise the viscosity of the synovial fluid present in the intra-articular cavity.\u003cbr\u003e Each package contains one vial of CondronilIALDUE syringe and a package insert. Two labels are included, indicating the batch number and expiration date. One label should be placed on the patient's medical record and the other should be given to the patient to ensure traceability.\u003cbr\u003e A substitute for synovial fluid which, thanks to its viscoelastic and lubricating properties, promotes the restoration of the rheological conditions of the joints, altered in the case of degenerative or post-traumatic conditions.\u003cbr\u003e By improving the characteristics of the synovial fluid, the product has a protective effect on the joints and promotes improved joint function and the reduction of painful symptoms. \u003cbr\u003eCondronilIALDUE acts only at the level of the joint into which it is injected without exerting any systemic action.\u003cbr\u003e Indicated for intra-articular injections only and should only be dispensed by a physician who has received specific training in the intra-articular injection technique.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e Remove any joint effusion before injecting CondronilIALDUE; the same needle must be used for removing the effusion and injecting CondronilIALDUE. Remove the protective cap from the syringe, taking particular care to avoid contact with the opening. Securely screw the 18- to 22-gauge needle onto the Luer-type locking collar following the instructions below.\u003cbr\u003e Before injecting, treat the site with a suitable disinfectant.\u003cbr\u003e Inject CondronilIALDUE using aseptic technique. Inject only into the joint cavity. \u003cbr\u003eIt is recommended to carry out an initial cycle of three treatment sessions, at intervals of one week from each other, followed by maintenance sessions if necessary, according to the medical prescription.\u003cbr\u003e INSTRUCTIONS FOR ASSEMBLING THE NEEDLE ON THE SYRINGE\u003cbr\u003e A. Carefully unscrew the cap from the tip of the syringe, taking special care to avoid contact with the opening.\u003cbr\u003e B. Gently grasp the needle shield and fit the needle onto the Luer-lock fitting, screwing firmly until you feel slight back pressure to ensure a watertight seal and prevent gel leakage during administration.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Sodium hyaluronate (20 mg\/ml), sodium chloride, sodium phosphate monobasic dihydrate, sodium phosphate dibasic dodecahydrate, water for injection\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e \u003cbr\u003eBefore use, check the integrity of the syringe and the expiration date. Do not use needles other than those indicated. The product should not be injected into an infected or severely inflamed joint. Injection should be avoided in cases of active infection or inflammatory conditions of the skin near the injection site. Since no clinical data are available on the use of hyaluronate in children, treatment with CondronilIALDUE is not recommended in these cases. Following the intra-articular injection, patients should be advised to avoid physically demanding activities for the joint and to resume normal activities after a couple of days.\u003cbr\u003e CondronilIALDUE is a single-use product; quality and sterility are guaranteed only if the syringe is sealed. Any residue must therefore be discarded and not reused, even after re-sterilization. \u003cbr\u003eDo not use the product if the packaging is already opened or damaged.\u003cbr\u003e The syringe complete with needle must be discarded immediately after use, even if the solution has not been completely administered. After use, dispose of according to current regulations.\u003cbr\u003e There are incompatibilities between sodium hyaluronate and quaternary ammonium compounds, such as benzalkonium chloride solutions. Therefore, avoid contact between CondronilIALDUE and these substances.\u003cbr\u003e Some transient side effects may occur following the injection of CondronilIALDUE, such as pain, stiffness, warmth, redness, or swelling. These side effects can be relieved by applying ice to the treated joint. They usually disappear after a short time. If symptoms persist, consult a doctor. Any other unwanted side effects associated with the injection of CondronilIALDUE should be reported to your doctor. \u003cbr\u003eKeep out of reach of children.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store CondronilIALDUE at 2-25°C (36-77°F) in a dry place in the original carton. Protect from light, heat, and frost.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pre-filled syringe containing 2 ml of pyrogen-free gel, sterilized by moist heat.\u003c\/div\u003e","brand":"DOC GENERICI SRL","offers":[{"title":"Default Title","offer_id":50734570996046,"sku":"974003749","price":52.16,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/974003749.jpg?v=1768763009"},{"product_id":"hyalotend-3-sir-20mg-2ml","title":"HYALOTEND 20MG\/2ML INTRA-ARTICULAR SYRINGE 3 PIECES","description":"\u003ch1\u003e HYALOTEND\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e\n\n \u003cb\u003eDescription\u003c\/b\u003e \u003cbr\u003eCE Medical Device (Dir. 93\/42\/EEC) Class III. Sterile.\u003cbr\u003e A viscous solution of hyaluronic acid sodium salt (500-730 kDa) obtained by bacterial fermentation in buffered saline, for peritendinous injection. The solution (20 mg\/2 ml) is contained in a pre-filled syringe and is supplied sterile. Hyaluronic acid is a major component of synovial fluid, is produced in the normal tendon sheath, and is a major component of the tendon's extracellular matrix. The administration of exogenous hyaluronic acid sodium salt into the peritendinous space, thanks to its viscoelastic properties, reduces surface friction of the tendons, increases sliding capacity, reduces pain, and improves tendon function in tendinopathy, thus accelerating the return to normal activities and sports.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e \u003cbr\u003eThe product should be administered only by experienced medical personnel. Use an ultrasound probe to guide the injection, if necessary. All rules regarding aseptic administration technique must be strictly followed. Do not use concomitantly with disinfectants containing quaternary ammonium salts, as hyaluronic acid may precipitate in their presence. Use a suitable sterile needle (21-25 G) according to medical advice. Discard the syringe and needle after single use.\u003cbr\u003e Administer 3 peritendinous injections of the product at weekly intervals, as directed by your doctor. If necessary, multiple tendons can be treated simultaneously. Each syringe is intended for the injection of a single tendon. Repeated treatments may be performed if necessary.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComposition\u003c\/b\u003e\u003cbr\u003e Main component: hyaluronic acid sodium salt.  \u003cbr\u003eOther ingredients: sodium chloride, dibasic sodium phosphate dodecahydrate, monobasic sodium phosphate dihydrate, water for injections.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e HYALOTEND should not be administered to patients with known hypersensitivity to any component of the product. Peritendineal injections of HYALOTEND are contraindicated in cases of infections or skin diseases at the injection site. HYALOTEND has not been tested in pregnant women or individuals under 18 years of age and is therefore contraindicated in these patient populations.  \u003cbr\u003eDo not use the product after the expiration date shown on the package. Do not use the product if the package is opened or damaged: the sterility of the solution is guaranteed as long as the package is closed and intact. The syringe is for single use only, meaning it should be used for a single injection only. The assembled syringe must be discarded immediately after use, regardless of whether the solution has been completely administered. If a syringe is used for a subsequent injection, there is a risk of contamination that could lead to illness, infection, and\/or serious harm to the patient. If the product is reprocessed and\/or reused, Fidia Farmaceutici cannot guarantee its performance, functionality, material structure, cleanliness, or sterility. Reprocessing and\/or reuse may cause serious harm to the health and safety of the patient. Dispose of the product according to current regulations after use. As with any invasive joint procedure, care should be taken not to overload the joint immediately after the peritendinous injection. Keep out of reach of children.  \u003cbr\u003e\u003cbr\u003e\u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store below 25°C. Do not freeze.\u003cbr\u003e Shelf life in unopened packaging: 36 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Box containing 3 pre-filled syringes, each sealed in a blister.\u003cbr\u003e The 20 mg\/2 ml solution of hyaluronic acid sodium salt contained in the pre-filled syringe is sterilized with steam.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e 10000123\u003c\/div\u003e","brand":"FIDIA FARMACEUTICI SPA","offers":[{"title":"Default Title","offer_id":50734585741646,"sku":"980185730","price":89.25,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-370576.jpg?v=1768763072"},{"product_id":"savetyal-sir-intra-art-2ml","title":"PRE-FILLED INTRA-ARTICULAR SYRINGE SAVETYAL HYALURONIC ACID 40MG 2 ML","description":"\u003ch1\u003e SAVETYAL®\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Hyaluronic acid gel for intra-articular infiltration.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e 2 ml pre-filled syringe.\u003cbr\u003e\u003cbr\u003e\n\u003c\/div\u003e","brand":"MASTELLI SRL","offers":[{"title":"Default Title","offer_id":50734591770958,"sku":"982593396","price":38.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-301285.jpg?v=1768763113"},{"product_id":"tralox-2-sir-intra-art-ialur","title":"TRALOX 2% INTRA-ARTICULAR SYRINGE HYALURONIC ACID 2 ML 1 PIECE","description":"\u003ch3\u003e Tralox 2% Pre-Filled Syringe Hyaluronic Acid\u003c\/h3\u003e\n\n\n\u003cp\u003e Medical Device.\u003cbr\u003e\n Hyaluronic acid sodium salt 1.6% (32g) for intra-articular injection.\u003c\/p\u003e\n\n\n\u003cp\u003e Composition\u003cbr\u003e\n Sodium Hyaluronic Acid, Sodium Chloride, Sodium Phosphate Monobasic Dihydrate, Sodium Phosphate Dibasic Dodecahydrate, Water ppi.\u003c\/p\u003e\n\n\n\u003cp\u003e Format\u003cbr\u003e\n 2 ml pre-filled syringe.\u003cbr\u003e\n\u003c\/p\u003e\n\n","brand":"NALKEIN ITALIA SRL","offers":[{"title":"Default Title","offer_id":50734596817230,"sku":"984778910","price":49.4,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/984778910.jpg?v=1768763161"},{"product_id":"fasto3-emulgel-100g","title":"FASTO3 EMULGEL FOR TRAUMATIC ARTHRITIS RHEUMATIC PAIN 100 G","description":"\u003ch1\u003e FastO3\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e\n\u003ch2\u003e EMULGEL\u003c\/h2\u003e \u003cb\u003eDescription\u003c\/b\u003e \u003cbr\u003eAn innovative medical device useful for acute and chronic pain caused by trauma, arthritis, and rheumatism. Its active ingredients work synergistically to rapidly reduce pain: Ozolipoile (ozone stabilized in oleic acid with alpha lipoic acid and vitamin E acetate) reduces pain and inflammation; glucosamine and chondroitin sulfate prevent and counteract joint cartilage wear. Effective from the first application, it acts quickly and effectively on the symptoms of pain and inflammation caused by rheumatism, arthritis, and trauma.\u003cbr\u003e It does not create any uncomfortable sensations during use.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e Apply the product to the painful area and massage carefully.\u003cbr\u003e It is advisable to use the product two or three times a day, until the painful symptoms subside or, alternatively, according to your doctor's advice.\u003cbr\u003e Formula also for use with ultrasound and electrophoresis.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e \u003cbr\u003eOzolipoile (ozone stabilized in oleic acid with alpha lipoic acid and vitamin E acetate), Arnica montana flower extract, Harpagophytum procumbens root extract, Ribes nigrum leaf extract, glycerin, bromelaine, panthenol, menthol, glucosamine, hydrolyzed glycosaminoglycans.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eGluten-\u003c\/b\u003e free and colorant-free.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e External use.\u003cbr\u003e Do not ingest.\u003cbr\u003e Keep the product out of reach of children.\u003cbr\u003e Do not use the device after the expiration date.\u003cbr\u003e Do not use if package is damaged.\u003cbr\u003e Prolonged use of topical products may cause sensitization. If this occurs, discontinue use and consult your doctor.\u003cbr\u003e Wash your hands thoroughly before using the medical device. It is recommended to carefully close the tube after use.\u003cbr\u003e Do not use in case of known hypersensitivity to any component of the product.\u003cbr\u003e Do not apply to broken skin.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e \u003cbr\u003eStore in a dry place, away from heat sources and direct sunlight.\u003cbr\u003e Shelf life when packaged intact: 40 months.\u003cbr\u003e Shelf life after opening: 6 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e 100g tube.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCode\u003c\/b\u003e 916\u003c\/div\u003e","brand":"ERREKAPPA EUROTERAPICI SPA","offers":[{"title":"Default Title","offer_id":50734607860046,"sku":"988754545","price":24.75,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-328832_fa15e830-11f0-45e8-b040-c8b65987675b.jpg?v=1768763221"},{"product_id":"orthovisc-sir-2ml-15mg-ml","title":"ORTHOVISC INTRA-ARTICULAR SYRINGE 2 ML 15 MG\/ML","description":"\u003ch1\u003e ORTHOVISC\u003cbr\u003e ORTHOVISC\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e\n\n \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Medical device.\u003cbr\u003e Sodium hyaluronate for intra-articular injection. \u003cbr\u003eSodium hyaluronate is a high molecular weight polysaccharide composed of sodium glucuronate and N-acetylglucosamine. Sodium hyaluronate is distributed throughout the body and is present in high concentrations in tissues such as the vitreous humor, synovial fluid, umbilical cord, and dermis. Sodium hyaluronate acts as a tissue lubricant and is believed to play an important role in modulating the interaction between adjacent tissues. It can also act as a viscoelastic support, maintaining tissue separation. Different sodium hyaluronate preparations may have different molecular weights, but they are believed to always have the same chemical structure.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e \u003cbr\u003eStore at 2°C to 25°C. Allow to reach room temperature approximately 20-45 minutes before use. Not for intravenous injection. The required amount is slowly infused into the selected joint space through a non-rigid, ISO\/ANSI compliant, pivot-type hypodermic needle of appropriate diameter. Diameters used for knee injections are 18-21 gauge. The final selection for any procedure must be determined by the physician. The volume varies depending on the size of the joint space but should not exceed 2 ml for the knee and other large joints or 1 ml for small joints. It is the physician's responsibility to determine the appropriate volume to ensure the joint is not overfilled. The recommended treatment regimen is 3 injections spaced one week apart for each treatment cycle, with a maximum treatment cycle for an individual joint in a 6-month period. Remove any effusion from the joint before injecting the product. Don't overfill the joint space. \u003cbr\u003e\u003cbr\u003e\u003cb\u003eContraindications\u003c\/b\u003e\u003cbr\u003e The following pre-existing conditions may constitute relative or absolute contraindications to the use of the products:\u003cbr\u003e – known sensitivity to any of the ingredients contained in the two products;\u003cbr\u003e – pre-existing infections of the skin region of the intended injection site;\u003cbr\u003e – known joint infections;\u003cbr\u003e – known systemic bleeding abnormalities.\u003cbr\u003e The products may contain traces of gram-positive bacterial proteins and are contraindicated in patients with a history of similar allergies.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e \u003cbr\u003eNormal precautions for injections into joints are recommended. Only medical personnel familiar with accepted injection techniques for administering agents into joint spaces should inject sodium hyaluronate for this application. Do not use excessive amounts of sodium hyaluronate and keep the patient under close observation. Do not overfill the space. If pain increases during the injection, stop the injection and withdraw the needle. If any abnormalities occur following administration of the products, patients should contact their physician immediately. Do not use if the inner packaging (pouch) is opened or damaged. For intra-articular injection. Not for intravenous injection. The sale and use of this medical device are restricted to a physician or under the supervision of a physician. Single use only. Do not resterilize.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e \u003cbr\u003eStore products at a temperature between 2°C and 25°C. Avoid freezing.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Orthosivisc: pack of 1 and 3 2 ml syringes.\u003cbr\u003e Orthosivisc mini (quantity for small joints): pack of 1 and 3 1 ml syringes.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCode\u003c\/b\u003e VROV1 \/ VROV3 \/ VR0M1 \/ VR0M3\u003c\/div\u003e","brand":"ALTAIR PHARMA SRL","offers":[{"title":"Default Title","offer_id":50734610841934,"sku":"902084755","price":62.7,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-091570.jpg?v=1768788581"},{"product_id":"sinovial-hl-32-sir-intra-art","title":"INTRA-ARTICULAR SYRINGE SINOVIAL HL 32 HYALURONIC ACID SODIUM SALT 16MG H-HA + 16MG H-LA\/1ML + NEEDLE 22 GAUGE + NEEDLE 29 GAUGE","description":"\u003ch1\u003e SINOVIAL HL 32 1 ml\u003c\/h1\u003e\n\u003ch2\u003e Hybrid 3.2% - 16 mg (H-HA) + 16 mg (L-HA)\/1 ml\u003c\/h2\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e \u003cbr\u003eMedical device designed to integrate synovial fluid, allowing the physiological and rheological properties of arthritic joints and tendons to be restored. \u003cbr\u003eThe HA chains of different molecular weights present in SINOVIAL HL 32 1 ml, thanks to a specific and patented solution treatment, interact with each other, giving SINOVIAL HL 32 1 ml unique rheological characteristics that allow the administration of higher concentrations of hyaluronic acid at the same solution viscosity. The HA chains of different molecular weights in SINOVIAL HL 32 1 ml provide greater resistance to hyaluronidase, since this enzyme is unable to recognize the conformation of these high and low molecular weight complexes. Therefore, SINOVIAL HL 32 1 ml is more suitable for in vivo applications in tissues. In vitro studies have been conducted to identify any incompatibilities and\/or interactions between SINOVIAL HL 32 1 ml and platelet-rich plasma (PRP), used for the intra-articular infiltrative treatment of osteoarthritis. The results obtained demonstrate that PRP does not alter the rheological behavior of sodium hyaluronate, which therefore retains its viscosupplementation function. Furthermore, the results of studies conducted on cultures of human mesenchymal stem cells (MSCs) differentiated into chondrocytes demonstrate that there is no cellular damage, an indicator of toxicity. There is therefore no reason to believe that the biocompatibility of SINOVIAL HL 32 1 ml is altered by the concomitant administration of PRP. \u003cbr\u003eSINOVIAL HL 32 1 ml, with its particular formula, belongs to the latest generation of treatments for osteoarthritis and is indicated in cases of pain or reduced mobility due to degenerative conditions (arthrosis), post-traumatic conditions and tendinopathies associated with joint disability.\u003cbr\u003e SINOVIAL HL 32 1 ml is also indicated in cases of acute and chronic tendinopathies and\/or those associated with joint disability and in the tendon repair process, even following surgical interventions.\u003cbr\u003e It reduces pain and promotes the recovery of associated joint and tendon mobility, acting only in the synovial cavity into which it is injected, without exerting any systemic action. \u003cbr\u003eFurthermore, thanks to its lubricating and viscoelastic properties, SINOVIAL HL 32 1 ml acts on the tendon sheath, improving tendon gliding and the physiological healing and repair processes, thus preventing the formation of adhesions in the post-operative period. Treatment may require up to three injections depending on the severity of the joint and\/or tendon degeneration. The appropriateness and frequency with which treatment can be repeated must be assessed by the physician for each individual patient, considering in each case the risk\/benefit ratio of the treatment.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e Aspirate any joint effusion before injecting SINOVIAL HL 32 1 ml. \u003cbr\u003eCarefully unscrew the syringe cap, holding the Luer Lock collar firmly between your fingers and taking particular care to avoid contact with the opening. Insert the needle into the Luer Lock collar of the syringe (22G or 29G needle included in the package) and screw it firmly until you feel a slight pressure, ensuring a watertight seal and preventing leakage during administration, while holding the Luer Lock collar firmly between your fingers.\u003cbr\u003e Inject SINOVIAL HL 32 1 ml at room temperature and under conditions of strict aseptic conditions, into the synovial space of the joint or into the tendon sheath\/peritendinous area, depending on the identified medical need.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e High molecular weight hyaluronic acid (H-HA) and low molecular weight hyaluronic acid (L-HA), sodium chloride, sodium phosphate and water for injections.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e \u003cbr\u003eSINOVIAL HL 32 1 ml can only be injected by a doctor.\u003cbr\u003e The contents of the pre-filled syringe are sterile. The syringe and needles are packaged in a sealed blister. The outer surface of the syringe is not sterile.\u003cbr\u003e Do not use SINOVIAL HL 32 1 ml after the expiry date shown on the package.\u003cbr\u003e Do not use SINOVIAL HL 32 1 ml if the packaging is open or damaged.\u003cbr\u003e The injection site must be on healthy skin. Do not inject via a vascular route. Do not inject outside the joint cavity, into the synovial tissue, or into the joint capsule. Do not administer SINOVIAL HL 32 1 ml in the presence of large intra-articular effusion.\u003cbr\u003e Do not re-sterilize. The device is intended for single use only. Do not reuse to avoid any risk of contamination.\u003cbr\u003e Once opened SINOVIAL HL 32 1 ml must be used immediately and discarded after use.\u003cbr\u003e Keep out of the reach and sight of children. \u003cbr\u003eAfter the injection, advise the patient to avoid all strenuous physical activity and to resume normal activities only after a few days.\u003cbr\u003e The presence of an air bubble does not affect the characteristics of the product.\u003cbr\u003e Do not mix SINOVIAL HL 32 1 ml with disinfectants such as quaternary ammonium salts or chlorhexidine as a precipitate may form.\u003cbr\u003e HL 32 1 ml may cause local side effects. Symptoms such as pain, heat, redness, or swelling may appear at the injection site when using SINOVIAL HL 32 1 ml. These side effects can be alleviated by applying ice to the treated area. They usually disappear after a short time. Physicians should ensure that patients are informed of any side effects that occur after treatment. \u003cbr\u003eSINOVIAL HL 32 1 ml must not be injected if the joint is infected or severely inflamed or if the patient has a skin condition or infection in the area of ​​the injection site.\u003cbr\u003e To date, no interactions are known between SINOVIAL HL 32 1 ml and other drugs. Based on in vitro data available to date, no chemical, physical, or biological interactions are known between SINOVIAL HL 32 1 ml and Platelet-Rich Plasma (PRP), used for the intra-articular infiltrative treatment of osteoarthritis.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store at room temperature, below 25°C, away from heat sources. Do not freeze.\u003cbr\u003e Shelf life when packaging is intact: 36 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack of:\u003cbr\u003e - 1 pre-filled syringe [16 mg (H-HA + 16 mg (L-HA) hyaluronic acid sodium salt in 1 ml of sodium chloride buffered saline solution];\u003cbr\u003e - 1 needle 29 G x ½\" TW (0.3 x 12 mm), for small joints;\u003cbr\u003e - 1 needle 22 G x 1 ½\" (0.7 x 40 mm), for large joints.\u003cbr\u003e  \u003cbr\u003e\u003cb\u003eCod.\u003c\/b\u003e 6000001359\u003c\/div\u003e","brand":"IBSA FARMACEUTICI ITALIA SRL","offers":[{"title":"Default Title","offer_id":50734625554766,"sku":"935184527","price":45.6,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-125017.jpg?v=1768763404"},{"product_id":"renehavis-sir-intra-art-0-7ml","title":"INTRA-ARTICULAR SYRINGE SODIUM HYALURONATE 15.4 MG 0.7 ML RENEHAVIS 1 PIECE","description":"\u003ch1\u003e RenehaVis\u003c\/h1\u003e \u003cb\u003eSODIUM HYALURONATE\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e Reduction of knee joint pain and stiffness in patients with synovial joint degeneration.\u003cbr\u003e The duration of effect in patients with grade 1 - 3 medial compartment osteoarthritis can be up to four months, as clinically demonstrated. \u003cbr\u003eThe effectiveness of RenehaVis is due to its biocompatibility and physiochemical properties. The LMW and HMW sodium hyaluronate contained in RenehaVis is a biopolymer composed of disaccharide units of N-acetylglucosamine and glucuronic acid obtained through the biosynthesis of Streptococcus equi, and has been shown to be identical to the sodium hyaluronate found in the human body. Sodium hyaluronate is naturally found in synovial joints, but may have been altered by degenerative or traumatic changes in the synovial joint. RenehaVis complements synovial sodium hyaluronate that has undergone alterations in molecular weight and concentration.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e RenehaVis injection must be performed by qualified and authorized healthcare personnel familiar with the intra-articular administration technique. \u003cbr\u003eThe administration schedule involves administration into the affected synovial joint space once a week and treatment can be up to a maximum of three injections, depending on the severity of the joint degeneration.\u003cbr\u003e Disinfect the injection site with an antiseptic and let it dry before injecting.\u003cbr\u003e In case of effusion, proceed with aspiration before injecting RenehaVis.\u003cbr\u003e The contents of the syringe are sterile and must be injected using a sterile needle, preferably of an appropriate size (recommended needle type: 25 G). The syringe is equipped with a Luer lock (6%).\u003cbr\u003e Discard the needle and syringe after use.\u003cbr\u003e\u003cbr\u003e It comprises two sterile, transparent sodium hyaluronate components in a phosphate-buffered saline solution contained in a pre-filled, dual-chamber syringe that allows a single administration by intra-articular injection into the synovial space of the joint. \u003cbr\u003eRenehaVis is a sterile, pre-filled, ready-to-use, double-chamber glass syringe containing:\u003cbr\u003e - Chamber 1 Low Molecular Weight (LMW) sodium hyaluronate 0.7 ml Sterile 2.2% sodium hyaluronate Molecular Weight 1 x 106 Da.\u003cbr\u003e - Chamber 2 High Molecular Weight Sodium Hyaluronate (HMW) 0.7 ml Sterile 1.0% Sodium Hyaluronate Molecular Weight 2 x 106 Da.\u003cbr\u003e RenehaVis 0.7ml LMW and 0.7ml HMW, sterilized by autoclave, is contained in a ready-to-use disposable glass syringe. The syringe is in turn contained in a blister pack, packaged in a cardboard box.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eContraindications\u003c\/b\u003e\u003cbr\u003e Do not inject RenehaVis if the injection site is infected or where you have a skin disease.\u003cbr\u003e Patients with known hypersensitivity to sodium hyaluronate.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e Do not use the product if the packaging is damaged.\u003cbr\u003e Do not use after the expiration date. \u003cbr\u003eSodium hyaluronate is produced through the fermentation of Streptococcus equi and is then rigorously purified. However, the physician should consider the potential immunological risk or other potential factors that may be associated with the injection of biological products in general.\u003cbr\u003e Do not use in children.\u003cbr\u003e Follow national or local guidelines for the safe use and disposal of needles. Treat any possible needle stick injury promptly.\u003cbr\u003e\u003cbr\u003e","brand":"MDT INT'L SA","offers":[{"title":"Default Title","offer_id":50734656586062,"sku":"913765879","price":93.1,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-047617_3af1fb34-7273-4898-a08f-7298533d595f.jpg?v=1734770697"},{"product_id":"md-poly-italia-10f-iniett-2ml","title":"MD-POLY ITALIA 10 INJECTABLE VIALS OF 2ML","description":"\u003ch1\u003e GUNA\u003cbr\u003e MD-POLY\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e\n\n \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Collagen-based medical device.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack of 10 2 ml vials.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e MD09\u003c\/div\u003e","brand":"GUNA SPA","offers":[{"title":"Default Title","offer_id":50734660485454,"sku":"930010780","price":91.2,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/930010780.jpg?v=1738064097"},{"product_id":"sinovial-16-sir-intra-art-0-8","title":"INTRA-ARTICULAR SYRINGE SINOVIAL 16 HYALURONIC ACID SODIUM SALT 0.8% 16MG\/2ML 2ML + NEEDLE 21 GAUGE","description":"\u003ch1\u003e SINOVIAL 16 2 ml\u003c\/h1\u003e\n\u003ch2\u003e 0.8% 16 mg\/2 ml\u003c\/h2\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e A synovial fluid substitute that restores the physiological and rheological properties of arthritic joints. This therapeutic effect is achieved by the specific characteristics of the hyaluronic acid used. The hyaluronic acid in SINOVIAL 16 2 ml, obtained through fermentation and not chemically modified, is excellently tolerable. By restoring the viscoelastic properties of synovial fluid, SINOVIAL 16 2 ml reduces pain and restores joint and tendon mobility. \u003cbr\u003eSINOVIAL 16 2 ml acts only at the level of the area into which it is injected, without exerting any systemic action. The improvement is immediate: after the first injection, the overall WOMAC index decreases, and starting from the third injection the decrease becomes statistically significant. \u003cbr\u003eIndicated for acute and chronic tendinopathies and\/or those associated with joint disability and in the tendon repair process, including following surgery. SINOVIAL 16 2 ml is a medical device designed to supplement synovial fluid, restoring the physiological and rheological properties of arthritic joints and tendons. In the joint, SINOVIAL 16 2 ml reduces pain and promotes recovery of joint and tendon mobility, acting only in the synovial cavity into which it is injected, without exerting any systemic action. Furthermore, SINOVIAL 16 2 ml, thanks to its lubricating and viscoelastic properties, acts at the level of the tendon sheath, where it improves tendon gliding and the physiological healing\/repair processes, thus preventing the formation of adhesions in the post-operative period.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e \u003cbr\u003eAspirate any joint effusion before injecting.\u003cbr\u003e Carefully unscrew the syringe cap, holding the Luer Lock collar firmly between your fingers and taking particular care to avoid contact with the opening. Insert the needle into the Luer Lock collar of the syringe (needle diameter between 18 and 22G) and screw it firmly until you feel a slight pressure to ensure a watertight seal and prevent leakage during administration, holding the Luer Lock collar firmly between your fingers.\u003cbr\u003e Inject SINOVIAL 16 2 ml at room temperature and under conditions of strict aseptic conditions, into the synovial space of the joint or into the tendon sheath\/peritendinous area, depending on the identified medical need.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e \u003cbr\u003e0.8% hyaluronic acid, highly purified sodium salt (molecular weight between 800 and 1,200 KDalton), sodium chloride, sodium phosphate, water for injections.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e SINOVIAL 16 2 ml can only be injected by a doctor.\u003cbr\u003e The contents of the pre-filled syringe are sterile.\u003cbr\u003e The syringe is packaged in a sealed blister. The outer surface of the syringe is not sterile.\u003cbr\u003e Do not use after the expiry date shown on the package.\u003cbr\u003e Do not use if packaging is open or damaged.\u003cbr\u003e The injection site must be on healthy skin.\u003cbr\u003e Do not inject intravascularly. Do not inject outside the joint cavity, into the synovial tissue, or into the joint capsule. Do not administer in the presence of large intra-articular effusion.\u003cbr\u003e Do not re-sterilize. The device is intended for single use only. Do not reuse to avoid any risk of contamination. \u003cbr\u003eOnce opened it must be used immediately and discarded after use.\u003cbr\u003e Keep out of the reach and sight of children.\u003cbr\u003e After intra-articular or tendon synovial injection, advise the patient to avoid all strenuous physical activity and to resume normal activities only after a few days.\u003cbr\u003e The presence of an air bubble does not affect the characteristics of the product.\u003cbr\u003e Do not mix SINOVIAL with disinfectants such as quaternary ammonium salts or chlorhexidine as a precipitate may form. \u003cbr\u003eExtra-articular infiltration of SINOVIAL 16 2 ml may cause local side effects. During the use of SINOVIAL 16 2 ml, symptoms such as pain, heat, redness, or swelling may appear at the injection site. These side effects can be alleviated by applying ice to the treated area. They usually disappear after a short time. Physicians should ensure that patients are informed of any side effects that occur after treatment.\u003cbr\u003e SINOVIAL 16 2 ml must not be injected if the joint is infected or severely inflamed or if the patient has a skin condition or infection in the area of ​​the injection site.\u003cbr\u003e The product should not be used in case of known hypersensitivity to sodium hyaluronate or other components.\u003cbr\u003e To date, no interactions between SINOVIAL 16 2 ml and other drugs are known. \u003cbr\u003eDo not mix with disinfectants such as quaternary ammonium salts or chlorhexidine as a precipitate may form.\u003cbr\u003e It should not be injected if an infected or severely inflamed joint is present, or if the patient has a skin condition or infection at the injection site. The product should not be used in cases of known hypersensitivity to sodium hyaluronate or any of the other ingredients.\u003cbr\u003e SINOVIAL 16 2 ml can only be injected by a doctor.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store at room temperature, below 25°C, away from heat sources. Do not freeze.\u003cbr\u003e Shelf life in intact packaging: 36 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack of 1 pre-filled syringe (16.0 mg of hyaluronic acid sodium salt in 2 ml of sodium chloride buffered saline solution).\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e 6000001294\u003c\/div\u003e","brand":"IBSA FARMACEUTICI ITALIA SRL","offers":[{"title":"Default Title","offer_id":50734663467342,"sku":"935407433","price":39.52,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/935407433.jpg?v=1768763699"},{"product_id":"siringa-intra-articolare-joinart-acido-ialuronico-1-6-2-ml-3-pezzi","title":"JOINART INTRA-ARTICULAR SYRINGE HYALURONIC ACID 1.6% 2 ML 3 PIECES","description":"\u003cfont size=\"5\"\u003e\u003cb\u003eFENI \u003ci\u003eX\u003c\/i\u003e\u003c\/b\u003e\u003c\/font\u003e \u003cfont size=\"2\"\u003ePHARMA\u003c\/font\u003e\u003cbr\u003e\u003cbr\u003e \u003cfont size=\"7\"\u003e\u003cb\u003eJOINART\u003c\/b\u003e\u003c\/font\u003e\u003cbr\u003e \u003cfont size=\"2\"\u003e32 mg\/2 ml\u003cbr\u003e\u003cbr\u003e Hyaluronic acid sodium salt 1.6%\u003c\/font\u003e\u003cbr\u003e\u003cbr\u003e  \u003cdiv align=\"justify\"\u003eJoinart is a substitute for synovial fluid in joints affected by degenerative or mechanical arthropathy, which causes pain or reduced mobility.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Joinart is a CE marked medical device compliant with MDD93\/42\/EEC directive, containing 16 mg\/ml of hyaluronic acid obtained by fermentation from a high molecular weight fraction (\u0026gt; 1500 kDa) and not chemically modified.\u003cbr\u003e Joinart is a clear, sterile, pyrogen-free, and viscoelastic solution supplied in a 2 ml syringe. Hyaluronic acid is a natural polysaccharide found in many human tissues, particularly synovial fluid, and acts in joints both as a lubricant for cartilage and ligaments and as a shock absorber. Many studies have shown that hyaluronic acid injections into joints affected by osteoarthritis restore the viscosity and elasticity of the synovial fluid, resulting in pain relief and improved joint mobility.   \u003cbr\u003eJoinart acts only at the level of the joint into which it is injected, without exerting any systemic action.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComposition\u003c\/b\u003e\u003cbr\u003e Main component: sterile hyaluronic acid sodium salt 1.6%. Other ingredients: sodium chloride, sodium phosphate, and water for injections.\u003cbr\u003e\u003cbr\u003e \u003cb\u003ePackaging\u003c\/b\u003e\u003cbr\u003e Joinart is supplied in a glass syringe containing 32 mg of hyaluronic acid in 2 ml of sodium chloride buffered saline solution, packaged in a blister pack.\u003cbr\u003e The contents of the syringe are sterilized by moist heat.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eInstructions for use\u003c\/b\u003e\u003cbr\u003e Remove any joint effusion before injecting Joinart; the same needle should be used for removing the effusion and injecting Joinart. Remove the protective cap from the syringe, taking particular care to avoid contact with the opening.\u003cbr\u003e Screw the 18 to 22 gauge needle securely onto the Luer-type locking collar to ensure a leak-proof seal. \u003cbr\u003eBefore injection, treat the site with a suitable antiseptic solution. Inject Joinart using aseptic technique. Inject only into the joint cavity.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eAdministration\u003c\/b\u003e\u003cbr\u003e Joinart must be administered weekly for a total of three weeks or in any case according to the doctor's prescription.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e • The contents of the pre-filled syringe are sterile.\u003cbr\u003e The syringe is packaged in a sterile blister.\u003cbr\u003e The surface of the syringe is not sterile.\u003cbr\u003e • Do not use Joinart after the expiry date shown on the package.\u003cbr\u003e • Do not use Joinart if the package or syringe is open or damaged.\u003cbr\u003e • The injection site must be on healthy skin.\u003cbr\u003e • Do not inject intravascularly. Do not inject outside the joint cavity, into tissues or synovial capsules.\u003cbr\u003e • Joinart has not been tested in pregnant or breastfeeding women.\u003cbr\u003e • Joinart is disposable and does not need to be resterilized. \u003cbr\u003e• Avoid the concomitant administration of Joinart with other products for intra-articular use in order to prevent any possible interaction.\u003cbr\u003e • Do not administer Joinart in the presence of large intra-articular effusion.\u003cbr\u003e • Once the package has been opened, Joinart must be used immediately and disposed of in accordance with current regulations.\u003cbr\u003e • Keep out of reach of children.\u003cbr\u003e • As with any invasive joint treatment, the patient is advised to avoid all strenuous physical activity for the first 2-3 days after the injection.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eContraindications\u003c\/b\u003e\u003cbr\u003e It should not be administered:\u003cbr\u003e • to patients with known sensitivity to hyaluronic acid and related compounds;\u003cbr\u003e • if you have an infection or skin disease near the injection site;\u003cbr\u003e • if the joint is infected or severely inflamed.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eSide effects\u003c\/b\u003e \u003cbr\u003eSome transient side effects may occur following the injection of Joinart, such as pain, stiffness, sensation of warmth, redness or swelling.\u003cbr\u003e These side effects can be alleviated by applying ice to the treated joint. They usually disappear after a short time. If symptoms persist, consult a doctor. As with any invasive joint treatment, septic arthritis may develop if proper precautions are not observed during the injection or if the injection site is not sterile.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eStorage and expiry\u003c\/b\u003e\u003cbr\u003e Joinart should be stored in its original packaging at a temperature between 0 and 25°C, away from direct sunlight and frost. The expiration date is indicated on the packaging.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e\u003cbr\u003e 0000000000001\u003cbr\u003e 0000000000002\u003c\/div\u003e","brand":"S.F. GROUP SRL","offers":[{"title":"Default Title","offer_id":50953098330446,"sku":"934812862","price":163.4,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-135417.jpg?v=1768765078"},{"product_id":"siringa-intra-articolare-preriempita-hymovis-mo-re-hyadd4-esadecillamide-acido-ialuronico-32mg-4ml-4-ml","title":"PRE-FILLED INTRA-ARTICULAR SYRINGE HYMOVIS MO RE HYADD4 HEXADECILLAMIDE HYALURONIC ACID 32MG\/4ML 4 ML","description":"\u003ch1\u003e HYMOVIS MO.RE.\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e \u003cbr\u003eSterile hydrogel made with Hyadd4 (highly purified natural sodium hyaluronate hexadecylamide obtained by bacterial fermentation) in a buffered isotonic solution. Thanks to the high viscosity and elasticity provided by sodium hyaluronate hexadecylamide, HYMOVIS MO.RE. improves the lubricating and shock-absorbing function of synovial fluid, protecting cartilage and soft tissue from mechanical injury. These properties, combined with its prolonged permanence in the joints, allow HYMOVIS MO.RE. to relieve pain and improve joint function for up to six months in mild to moderate osteoarthritis of the hip and knee.\u003cbr\u003e Indicated for the treatment of patients with mild to moderate osteoarthritis of the knee and hip. The device is indicated for the treatment of osteoarthritis of any nature.\u003cbr\u003e HYMOVIS MO.RE. is administered exclusively by intra-articular injection. \u003cbr\u003eThe product must be administered exclusively by specialized medical personnel (e.g. orthopedic surgeon, rheumatologist, physiatrist, radiologist, sports doctor, etc.).\u003cbr\u003e Remove any joint effusion, if present, before administration. Inject intra-articularly only. Intra-articular injection must be performed according to the standard technique, with precise anatomical localization. In the hip, ultrasound or radioscopic guidance is recommended. Strictly follow all aseptic administration guidelines.\u003cbr\u003e Given its viscosity, inject HYMOVIS MO.RE. slowly into the joint using an appropriate sterile needle (18 or 20 G).\u003cbr\u003e Treatment consists of a single injection. No clinical data are available with more than one injection of HYMOVIS MO.RE.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Main component: Hyadd4 (sodium hyaluronate hexadecylamide), 32 mg\/4 ml. \u003cbr\u003eOther ingredients: sodium chloride, disodium hydrogen phosphate dodecahydrate, sodium dihydrogen phosphate dihydrate, water for injections.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e If there is venous or lymphatic stasis in the affected limb, HYMOVIS MO.RE. must not be injected into the joint.\u003cbr\u003e Do not administer to patients with known individual hypersensitivity to the components of the product or in case of infections or skin diseases in the injection area.\u003cbr\u003e Treatment should be avoided if the joint shows signs of acute inflammation.\u003cbr\u003e The safety and efficacy of using HYMOVIS MO.RE. with other intra-articular treatments have not been established.\u003cbr\u003e For the first 48 hours after the injection, the patient can perform all routine daily activities, but it is recommended not to overload the treated joint. \u003cbr\u003eThe syringe is for single use only; inject the contents into one joint only. The assembled syringe must be discarded immediately after use, regardless of whether the hydrogel has been completely administered.\u003cbr\u003e If the product is reprocessed and\/or reused, Fidia Farmaceutici cannot guarantee its performance, functionality, material structure, cleanliness, or sterility. Reuse may lead to illness, infection, and\/or serious harm to the patient or user.\u003cbr\u003e Do not use HYMOVIS MO.RE. after the expiration date printed on the carton. The expiration date applies to the product when stored properly in its original packaging.\u003cbr\u003e Do not use HYMOVIS MO.RE. if the package is open or damaged.\u003cbr\u003e Keep out of reach of children.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store in the original packaging between 2°C and 25°C. Do not freeze.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Case containing 1 pre-filled luer lock syringe.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e 10001309\u003c\/div\u003e","brand":"FIDIA FARMACEUTICI SPA","offers":[{"title":"Default Title","offer_id":50957248823630,"sku":"989259003","price":285.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-324203.jpg?v=1768765288"},{"product_id":"siringa-intra-articolare-condrotide-polinucleotidi-2-2-ml","title":"INTRA-ARTICULAR SYRINGE CHONDROTIDE POLYNUCLEOTIDES 2% 2 ML","description":"\u003cp\u003e Condrotide Intra-articular Syringe pre-filled - 2 ml\u003c\/p\u003e\n\n\n\u003cp\u003e Condrotide is a pre-filled syringe based on polynucleotides capable of acting as a substitute for synovial fluid in intra-articular treatments and is therefore very useful in cases of degenerative or post-traumatic conditions.\u003cbr\u003e\n Its composition, in fact, is capable of restoring the visco-elastic properties of the synovial fluid, in order to reduce the sensation of pain, often associated with difficulty in movement.\u003cbr\u003e\n Therefore, being able to improve the lubrication and protection of joints from mechanical stress, it can be used for infiltrations in case of arthrosis.\u003c\/p\u003e\n\n\n\u003cp\u003e The injection of the product must be performed by competent medical personnel.\u003cbr\u003e\n Perform 1 injection at weekly intervals, repeating the treatment for 3 weeks, unless otherwise indicated by the doctor.\u003cbr\u003e\r \nIn case of further treatment cycles, an interval of 6 months must be observed.\u003cbr\u003e\n For administration, it is recommended to use a needle with a gauge between 18 and 22 G.\u003cbr\u003e\n After administration it is important to keep the joint at rest to avoid localized pain.\u003c\/p\u003e\n\n\n\u003cp\u003e Side effects\u003cbr\u003e\n Following intra-articular injections, transient pain and\/or swelling and\/or effusion in the joint may occur, but also cases of acute inflammation characterized by joint pain, swelling, effusion and sometimes a sensation of heat and\/or stiffness in the joint.\u003cbr\u003e\n Hypersensitivity reactions including anaphylactic reaction, anaphylactoid reaction, anaphylactic shock and angioedema have also been reported.\u003c\/p\u003e\n\n\n\u003cp\u003e Contraindications\u003cbr\u003e\n Contraindicated in case of hypersensitivity to any of the components of the product.\u003cbr\u003e\r \nDo not use in case of: pre-existing infections in the skin area of ​​the intended injection site; known infection in the target joint; known systemic coagulation disorders; active tuberculosis; herpes simplex keratitis; acute psychosis; systemic mycoses and parasitoses (strongyloides infections).\u003cbr\u003e\n Do not inject intravascularly.\u003cbr\u003e\n Do not inject extra-articularly or into synovial tissue or capsule.\u003cbr\u003e\n Do not use concomitantly with disinfectants containing quaternary ammonium salts for skin preparation, as in their presence the hyaluronate may precipitate.\u003cbr\u003e\n Contraindicated during pregnancy or breastfeeding.\u003cbr\u003e\n Keep out of reach of children.\u003cbr\u003e\n Avoid freezing.\u003c\/p\u003e\n\n\n\u003cp\u003e Composition\u003cbr\u003e\n polynucleotides 20 mg\/ml, water for injections, sodium chloride, sodium phosphate monobasic dihydrate, sodium phosphate dibasic dodecahydrate\u003c\/p\u003e\n\n","brand":"MASTELLI SRL","offers":[{"title":"Default Title","offer_id":51036682420558,"sku":"939969073","price":57.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-193321.jpg?v=1768766113"},{"product_id":"siringa-intra-articolare-durolane-acido-ialuronico-gel-60-mg-3-ml","title":"INTRA-ARTICULAR SYRINGE DUROLANE HYALURONIC ACID GEL 60 MG 3 ML","description":"\u003ch1\u003e DUROLANE\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Class III medical device.\u003cbr\u003e DUROLANE is intended for use by intra-articular injection for the symptomatic treatment of mild to moderate osteoarthritis of the knee or hip and for the reduction of pain following arthroscopic procedures in the presence of osteoarthritis.\u003cbr\u003e DUROLANE is composed of biosynthetically produced, purified and stabilized hyaluronic acid. \u003cbr\u003eDUROLANE is absorbed by the body through the same metabolic pathway as endogenous hyaluronic acid.\u003cbr\u003e Hyaluronic acid is a natural component of synovial fluid and acts as a lubricant for cartilage and ligaments and a shock absorber in joints. Injecting hyaluronic acid into the joint to restore viscosity and elasticity can reduce pain and improve joint mobility.\u003cbr\u003e The product must be injected by a competent physician or in accordance with local legislation.\u003cbr\u003e\u003cbr\u003e single-dose preparation for single injection and must be injected only once per treatment.\u003cbr\u003e The recommended dose is 3 ml per knee, hip or shoulder joint.\u003cbr\u003e DUROLANE is indicated for the symptomatic treatment of mild to moderate osteoarthritis of the knee or hip. \u003cbr\u003eDUROLANE has also been approved for the symptomatic treatment of mild to moderate osteoarthritis of the ankle, shoulder, elbow, wrist, fingers, and toes. DUROLANE is also indicated for the treatment of pain following arthroscopic surgery in the presence of osteoarthritis for three months after the procedure.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eContent\u003c\/b\u003e\u003cbr\u003e 20 mg\/mL of non-animal hyaluronic acid stabilized in sodium chloride buffered saline pH 7.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eMode of action\u003c\/b\u003e\u003cbr\u003e Hyaluronic acid is a natural component of synovial fluid and acts as a lubricant for cartilage and ligaments and a shock absorber in joints. Injecting hyaluronic acid into the joint to restore viscosity and elasticity can reduce pain and improve joint mobility.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eDosage\u003c\/b\u003e \u003cbr\u003eDurolane is a single-dose preparation for single injection and should be injected only once per treatment. The recommended dose is 3 ml per knee, hip, or shoulder joint. The recommended dose is 1-2 ml for intermediate joints (e.g., elbow, ankle) and approximately 1 ml for small synovial joints (e.g., thumb).\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e - DUROLANE must not be injected if the synovial joint is infected or severely inflamed.\u003cbr\u003e - DUROLANE should not be injected if you have skin disease or active infection at or near the injection site.\u003cbr\u003e - DUROLANE must not be injected intravascularly or extra-articularly or into synovial capsules or tissues.\u003cbr\u003e - Do not resterilize DUROLANE as this may damage the product.\u003cbr\u003e - DUROLANE should be used with caution in patients with venous or lymphatic stasis in the leg.\u003cbr\u003e - DUROLANE has not been tested in pregnant or breastfeeding women or in children. \u003cbr\u003e- A single syringe of DUROLANE should be used for each joint to be treated.\u003cbr\u003e - As with any invasive joint surgery, the procedure carries a small risk of infection.\u003cbr\u003e - DUROLANE should not be injected in patients with known sensitivity to hyaluronic acid-based products.\u003cbr\u003e - The use of local anesthetics is not recommended in case of allergy or sensitivity of the patient to such products.\u003cbr\u003e - It is not recommended to perform the injection under fluoroscopic control and with the use of a contrast medium in case of allergy or sensitivity of the patient to the contrast medium.\u003cbr\u003e - In clinical studies, the effects of repeat injections into the knee with an interval between the first and second injections of less than 6 months have not been studied.\u003cbr\u003e - An increase in injection pressure could indicate incorrect extra-articular positioning of the needle or excessive filling of the joint.  \u003cbr\u003e- The efficacy of DUROLANE following arthroscopic procedures for diagnostic or examination purposes only or in the absence of concomitant osteoarthritis of the joint has not been established.\u003cbr\u003e - DUROLANE should be used with caution in patients with pre-existing chondrocalcinosis as the injection may trigger an acute attack of this condition.\u003cbr\u003e DUROLANE is a single-use product and must not be resterilized. Once the syringe is removed from the packaging, use immediately. Do not use the product if the blister pack or syringe is open or damaged.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Durolane should be stored in its original packaging at a temperature not exceeding 30°C. The expiration date is indicated on the packaging and the product should not be used after that date. Avoid freezing.\u003cbr\u003e Shelf life when packaging is intact: 36 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e \u003cbr\u003eSupplied in a 3 ml glass syringe with a Luer-Lok connector, in a blister pack. The contents of the syringe are sterile. The external part of the syringe is not sterile.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e 1082010\u003c\/div\u003e","brand":"BIOMEDICA ITALIA SRL","offers":[{"title":"Default Title","offer_id":51108611883342,"sku":"923544035","price":209.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-104740.jpg?v=1768766955"},{"product_id":"md-matrix-italia-10-vials-iniettabili-2-ml","title":"MD-MATRIX ITALIA 10 VIALS INJECTABLE 2 ML","description":"\u003cp\u003e Guna MD-Matrix is ​​a medical device in injectable vials of Guna based on porcine collagen, which is recommended for use by qualified healthcare personnel.\u003c\/p\u003e\n\n\n\u003cp\u003e How to use\u003cbr\u003e\n For correct use of the product, we recommend that you read the package leaflet carefully.\u003c\/p\u003e\n\n\n\u003cp\u003e Warnings\u003cbr\u003e\r \nUse by qualified healthcare personnel is recommended.\u003c\/p\u003e\n\n\n\u003cp\u003e Ingredients and Composition\u003cbr\u003e\n Porcine collagen, Citric acid, Nicotinamide, NaCl, Water for injection.\u003c\/p\u003e\n\n\n\u003cp\u003e Format\u003cbr\u003e\n 10 vials of 2 ml of solution for injection\u003c\/p\u003e\n\n","brand":"GUNA SPA","offers":[{"title":"Default Title","offer_id":51348323139918,"sku":"930010677","price":91.2,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/930010677.jpg?v=1768769049"},{"product_id":"siringa-intra-articolare-sinovial-50-acido-ialuronico-sale-sodico-2-50mg-2-5ml-2-5ml-ago-21-gauge","title":"INTRA-ARTICULAR SYRINGE SINOVIAL 50 HYALURONIC ACID SODIUM SALT 2% 50MG\/2.5ML 2.5ML + NEEDLE 21 GAUGE","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e SYNOVIAL 50 2.5 ml\u003c\/h1\u003e\n\u003ch2\u003e 2.0% 50 mg\/2.5 ml\u003c\/h2\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e \u003cbr\u003eSubstitute for synovial fluid, which allows to restore the physiological and rheological properties of arthritic joints. This therapeutic action is explained by the particular characteristics of the hyaluronic acid used. The hyaluronic acid contained in SINOVIAL 50 2.5 ml, obtained by fermentation and not chemically modified, has excellent tolerability. By restoring the viscoelastic properties of the synovial fluid, SINOVIAL 50 2.5 ml reduces pain and restores joint and tendon mobility.\u003cbr\u003e SINOVIAL 50 2.5 ml acts only at the level of the area in which it is injected, without exerting any systemic action. The improvement is immediate: already after the first injection, the global WOMAC index decreases and starting from the third injection the decrease becomes statistically significant. \u003cbr\u003eIndicated in cases of acute and chronic tendinopathies and\/or associated with joint disability and in the tendon repair process, even following surgery. SINOVIAL 50 2.5 ml is a medical device designed to integrate the synovial fluid, allowing the physiological and rheological properties of arthritic joints and tendons to be restored. In the joint, SINOVIAL 50 2.5 ml reduces pain and promotes the recovery of associated joint and tendon mobility, acting only in the synovial cavity into which it is injected, without exerting any systemic action. SINOVIAL 50 2.5 ml also, thanks to its lubricating and viscoelastic characteristics, acts at the level of the tendon sheath, where it improves tendon gliding (“Tendon gliding”) and the physiological healing\/repair processes, thus preventing the formation of adhesions in the post-operative course.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e \u003cbr\u003eAspirate any joint effusion before injecting.\u003cbr\u003e Carefully unscrew the syringe cap, holding the \"Luer Lock\" closure collar firmly between your fingers and taking special care to avoid contact with the opening. Insert the needle into the Luer Lock closure collar of the syringe (needle diameter between 18 and 22G) screwing it firmly, until you feel a slight pressure in order to ensure a watertight seal and prevent the leakage of liquid during administration, holding the \"Luer Lock\" closure collar firmly between your fingers.\u003cbr\u003e Inject SINOVIAL 50 2.5 ml at room temperature and under conditions of strict aseptic conditions, into the synovial space of the joint or into the tendon sheath\/peritendinous area, depending on the identified medical need.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e \u003cbr\u003e2% hyaluronic acid, highly purified sodium salt (molecular weight between 800 and 1,200 KDalton), sodium chloride, sodium phosphate, water for injections.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e SINOVIAL 50 2.5 ml can only be injected by a doctor.\u003cbr\u003e The contents of the pre-filled syringe are sterile.\u003cbr\u003e The syringe is packaged in a sealed blister. The outer surface of the syringe is not sterile.\u003cbr\u003e Do not use after the expiry date shown on the package.\u003cbr\u003e Do not use if packaging is open or damaged.\u003cbr\u003e The injection site must be on healthy skin.\u003cbr\u003e Do not inject vascularly. Do not inject outside the joint cavity, into the synovial tissue or into the joint capsule. Do not administer in the presence of large intra-articular effusion.\u003cbr\u003e Do not re-sterilize. The device is intended for single use only. Do not reuse to avoid any risk of contamination. \u003cbr\u003eOnce opened it must be used immediately and discarded after use.\u003cbr\u003e Keep out of the reach and sight of children.\u003cbr\u003e After intra-articular or tendon synovial injection, advise the patient to avoid all intense physical activity and to resume normal activities only after a few days.\u003cbr\u003e The possible presence of an air bubble does not affect the characteristics of the product.\u003cbr\u003e Do not mix SINOVIAL 50 2.5 ml with disinfectants such as quaternary ammonium salts or chlorhexidine as a precipitate may form. \u003cbr\u003eExtra-articular infiltration of SINOVIAL 50 2.5 ml may cause local side effects. During the use of SINOVIAL 50 2.5 ml, symptoms such as pain, heat, redness or swelling may appear at the injection site. These secondary manifestations can be alleviated by applying ice to the treated area. They usually disappear after a short time. The physician must ensure that patients inform him of any side effects that occur after treatment.\u003cbr\u003e SINOVIAL 50 2.5 ml must not be injected if the joint is infected or severely inflamed or if the patient has a skin condition or infection in the area of ​​the injection site.\u003cbr\u003e The product should not be used in case of known hypersensitivity to sodium hyaluronate or other components.\u003cbr\u003e To date, no interactions between SINOVIAL 50 2.5 ml and other drugs are known. \u003cbr\u003eDo not mix with disinfectants such as quaternary ammonium salts or chlorhexidine as a precipitate may form.\u003cbr\u003e It should not be injected if the joint is infected or severely inflamed or if the patient has a skin condition or infection at the injection site. The product should not be used in case of known hypersensitivity to sodium hyaluronate or other components.\u003cbr\u003e SINOVIAL 50 2.5 ml can only be injected by a doctor.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store at room temperature and in any case below 25 °C and away from heat sources. Do not freeze.\u003cbr\u003e Validity with intact packaging: 36 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack of 1 pre-filled syringe (50.0 mg hyaluronic acid sodium salt in 2.5 ml sodium chloride buffered saline) and 1 needle 21G x 1 ½\" (0.8 x 40 mm).\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e 6000001307\u003c\/div\u003e","brand":"IBSA FARMACEUTICI ITALIA SRL","offers":[{"title":"Default Title","offer_id":51348344865102,"sku":"931341705","price":96.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/931341705.jpg?v=1768769056"},{"product_id":"siringa-hyalganbio-intra-articolare-20mg-2-ml","title":"HYALGANBIO INTRA-ARTICULAR SYRINGE 20MG 2 ML","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e HYALGANBIO SYRINGE\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Solution for injection for intra-articular use.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e sodium chloride, sodium phosphate monobasic dihydrate, sodium phosphate dibasic dodecahydrate, water for injections qs to 2 ml.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Validity with intact packaging: 36 months.\u003cbr\u003e Storage conditions: 2 to 25 °C.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e 20 mg\/2 ml pre-filled syringe.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e 10000119\u003c\/div\u003e","brand":"FIDIA FARMACEUTICI SPA","offers":[{"title":"Default Title","offer_id":52605210067278,"sku":"975068483","price":39.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/975068483.jpg?v=1768772661"},{"product_id":"siringa-intra-articolare-coxarthrum-acido-ialuronico-3ml","title":"INTRA-ARTICULAR SYRINGE COXARTHRUM HYALURONIC ACID 3ML","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e Coxarthrum\u003c\/h1\u003e \u003cb\u003eDISPOSABLE SYRINGE\u003c\/b\u003e\u003cbr\u003e  \u003cbr\u003eto restore the hip joint space, reduce pain and restore joint mobility by replenishing the viscoelasticity of the pathological synovial fluid in arthritic joints.\u003cbr\u003e - Primary coxarthrosis (whatever the radiological stage);\u003cbr\u003e - Coxarthrosis and associated general factors:\u003cbr\u003e • ineffectiveness of usual treatments;\u003cbr\u003e • intolerance and\/or contraindications to the use of AINS and\/or painkillers;\u003cbr\u003e • polymedication (arterial hypertension, diabetes, obesity, cardiovascular and gastrointestinal problems);\u003cbr\u003e • contraindications to the implantation of a prosthesis (young subject and various contraindications related to the patient's condition.\u003cbr\u003e - Early stage coxarthrosis in young subjects (radiological stages I and II).\u003cbr\u003e - Coxarthrosis following trauma:\u003cbr\u003e • sequelae of joint fractures;\u003cbr\u003e • arthroscopy and injection of COXARTHRUM after intra-articular lavage.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use:\u003c\/b\u003e\u003cbr\u003e a single intra-articular injection. \u003cbr\u003eThe treatment can be repeated once in the second or third month after the first injection if the pain returns to the initial stage.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCharacteristics:\u003c\/b\u003e\u003cbr\u003e implantable viscoelastic device whose active ingredient is sodium hyaluronate, a natural derivative of hyaluronic acid, obtained with the genetic engineering technique, with a high molecular weight (2,400,000 daltons) and high concentration (25 mg\/ml).\u003cbr\u003e The high molecular weight combined with the high concentration of hyaluronic acid is an essential factor of efficacy in the symptomatic treatment of hip osteoarthritis.\u003cbr\u003e It does not contain any animal protein and is not chemically cross-linked, thus eliminating any risk of potential allergies and cytotoxicity, and guarantees perfect tolerance and safety of use.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings:\u003c\/b\u003e\u003cbr\u003e Do not use quaternary ammonium (Benzalkonium Chloride) for skin disinfection at the time of intra-articular injection.\u003cbr\u003e  \u003cbr\u003e\u003cb\u003eContraindications:\u003c\/b\u003e\u003cbr\u003e Do not administer if the patient has a known hypersensitivity to Sodium Hyaluronate.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents:\u003c\/b\u003e\u003cbr\u003e sodium hyaluronate (FB); sodium chloride; water for injection.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e RCX1013130","brand":"LCA S.A.","offers":[{"title":"Default Title","offer_id":52783821422926,"sku":"912943420","price":95.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-051870.jpg?v=1745980199"},{"product_id":"md-knee-italia-10-flaconcini-iniettabili-2-ml","title":"MD-KNEE ITALIA 10 INJECTABLE VIALS 2 ML","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e GUN\u003cbr\u003e MD-KNEE\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e\n\n \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Collagen-based medical device.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack of 10 2 ml bottles.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e MD03\u003c\/div\u003e","brand":"GUNA SPA","offers":[{"title":"Default Title","offer_id":52783839019342,"sku":"930010133","price":91.2,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/930010133.jpg?v=1768773724"},{"product_id":"md-lumbar-10-flaconcini-iniettabili-2-ml","title":"MD-LUMBAR 10 INJECTABLE VIALS 2 ML","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e MD-LUMBAR\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e \u003cbr\u003eMedical device useful for improving the mobility of the joints of the lumbosacral area of ​​the spine, whose primary therapeutic treatment consists of the following functions:\u003cbr\u003e 1. Barrier effect.\u003cbr\u003e 2. Lubricating activity.\u003cbr\u003e 3. Mechanical support in case of ongoing drug therapy.\u003cbr\u003e The use of MD-LUMBAR by qualified healthcare personnel in private or public healthcare facilities is recommended for:\u003cbr\u003e - improve lumbar mobility; - promote muscle relaxation in the lumbosacral area;\u003cbr\u003e - support the lumbar muscle structures;\u003cbr\u003e - relieve localized pain, pain at rest or caused by movement and postural defects.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e MD-LUMBAR can be used alone or combined with other medical devices from the same line, in order to guarantee personalized treatment based on the individual clinical picture. \u003cbr\u003eIn cases where supportive treatment is required for the onset of acute pain, MD-LUMBAR can be combined with MD-NEURAL, MD-POLY and MD-MUSCLE (one or more of these).\u003cbr\u003e Furthermore, in cases where tissue matrix support therapy is required or a slowing down of physiological aging is necessary, MD-LUMBAR can be combined with MD-MATRIX and MD-TISSUE.\u003cbr\u003e\u003cbr\u003e \u003cu\u003ePeriatric therapeutic protocol\u003c\/u\u003e :\u003cbr\u003e 2 treatments for the first 2 weeks; 1 treatment until symptoms improve (on average 8-10 sessions).\u003cbr\u003e\u003cbr\u003e Chronic conditions: continue with 1 treatment per week for one month until symptoms improve, and then with 1 treatment per month, or – as needed – every 45-50 days.\u003cbr\u003e\u003cbr\u003e The application area must be aseptic; insert the needle close to the lumbar and lumbosacral joints to a depth of 3-4 mm. \u003cbr\u003eFor this use of the medical device, the use of the following materials and accessories is recommended:\u003cbr\u003e • Material to ensure skin asepsis: disposable glove, iodine-based solution, alcohol solution, sterile gauze, ethyl chloride-based skin spray.\u003cbr\u003e • Needles: sterile 27 G.\u003cbr\u003e • Syringes: 5 or 10 cc, depending on the quantity of solution to be injected.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Collagen of porcine origin.\u003cbr\u003e Excipients: Hamamelis, NaCl, water for injection.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e Disposable.\u003cbr\u003e No case of hypersensitivity to MD-LUMBAR has been reported.\u003cbr\u003e Contains collagen of animal origin from porcine species. Patients with known hypersensitivity to the component or excipients must first undergo an injection test in the arm and be kept under observation for one hour.\u003cbr\u003e Low back pain requires differential diagnosis from herniated discs, pain secondary to primary or metastatic tumors; reflected or referred pain of visceral origin. \u003cbr\u003eSlight redness at the injection area may be due to the mechanical effect of the needle or a skin reaction.\u003cbr\u003e The application may cause burning\/pain symptoms at the injection sites, which generally resolve within 5-10 minutes after the end of treatment.\u003cbr\u003e Skin cleaning\/disinfection is required before and after application.\u003cbr\u003e Any pyogenic bacteria may produce an abscess in the injection area.\u003cbr\u003e Keep out of the reach and sight of children.\u003cbr\u003e Do not use after expiration.\u003cbr\u003e Use the product immediately after opening.\u003cbr\u003e Do not use if seal is broken or tampered with.\u003cbr\u003e After opening, the contents of the vial must be injected immediately.\u003cbr\u003e Do not use if packaging is damaged.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store at a temperature between 2°C and 30°C, protect from sunlight and frost.\u003cbr\u003e The expiry date refers to the product in its intact packaging, stored correctly.\u003cbr\u003e  \u003cbr\u003e\u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack of 10 sterile 2 ml vials\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e MD04\u003c\/div\u003e","brand":"GUNA SPA","offers":[{"title":"Default Title","offer_id":52783839084878,"sku":"930010653","price":91.2,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/930010653.jpg?v=1745980323"},{"product_id":"md-shoulder-italia-10-flaconcini-iniettabili-2-ml","title":"MD-SHOULDER ITALIA 10 INJECTABLE VIALS 2 ML","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e MD-SHOULDER\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e \u003cbr\u003eMedical device useful for improving joint mobility of the shoulder and upper limb, whose primary therapeutic treatment consists of the following functions:\u003cbr\u003e 1. Barrier effect.\u003cbr\u003e 2. Lubricating activity.\u003cbr\u003e 3. Mechanical support in case of ongoing drug therapy.\u003cbr\u003e The use of MD-SHOULDER is recommended by qualified healthcare personnel, in private or public healthcare facilities for:\u003cbr\u003e - improve the mobility of the shoulder joint and upper limb;\u003cbr\u003e - promote muscle relaxation;\u003cbr\u003e - support muscle structures;\u003cbr\u003e - relieve localized pain and pain caused by movement.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e MD-SHOULDER can be used alone or combined with other medical devices from the same line, in order to guarantee personalized treatment based on the individual clinical picture. \u003cbr\u003eIn cases where supportive treatment is required for the onset of acute pain, MD-SHOULDER can be combined with MD-NEURAL, MD-POLY and MD-MUSCLE (one or more of these).\u003cbr\u003e Furthermore, in cases where tissue matrix support therapy is required or a slowing down of physiological aging is necessary, MD-SHOULDER can be combined with MD-MATRIX and MD-TISSUE.\u003cbr\u003e\u003cbr\u003e \u003cu\u003eTherapeutic protocol\u003c\/u\u003e :\u003cbr\u003e 1-2 treatments per week for 10 consecutive weeks.\u003cbr\u003e\u003cbr\u003e Method of administration: periarticular injection (the application area must be aseptic; insert the needle close to the joint to a depth of 2-4 mm).\u003cbr\u003e For this use of the medical device, the use of the following materials and accessories is recommended:\u003cbr\u003e • Material to ensure skin asepsis: disposable glove, iodine-based solution, alcohol solution, sterile gauze, ethyl chloride-based skin spray.\u003cbr\u003e • Needles: sterile 27 G. \u003cbr\u003e• Syringes: 5 or 10 cc, depending on the quantity of solution to be injected.\u003cbr\u003e\u003cbr\u003e Method of administration: intra-articular injection.\u003cbr\u003e For this use of the medical device, the use of the following materials and accessories is recommended:\u003cbr\u003e • Material to ensure skin asepsis: disposable glove, iodine-based solution, alcohol solution, sterile gauze, ethyl chloride-based skin spray. The application of local anesthetic on the treated skin is recommended.\u003cbr\u003e • Needles: sterile 22 G.\u003cbr\u003e • Syringes: 5 or 10 cc, depending on the quantity of solution to be injected.\u003cbr\u003e  \u003cbr\u003e- Intra-articular injection of the shoulder, anterior: The patient's hand is placed on the thigh, while the shoulder muscles are relaxed. The glenohumeral joint can be palpated with the fingers between the coracoid process and the humeral head. Since the shoulder is rotated inward, the humeral head can be palpated by rotating inward and the joint space can be felt as a depression located lateral to the coracoid process. Insert a 22-gauge needle lateral to the coracoid process. Direct the needle into the joint space.\u003cbr\u003e  \u003cbr\u003e- Intra-articular injection of the shoulder, posterior aspect: The posterior aspect of the shoulder joint can be located by rotating the patient's arm. This position can be achieved by placing the patient's ispilateral hand on the contralateral shoulder. The humeral head can be palpated by placing a finger posteriorly on the acromion, while the shoulder is rotated. Insert a 22-gauge needle approximately 1 cm inferior to the posterior tip of the acromion and direct it anteriorly and medially.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Collagen of porcine origin.\u003cbr\u003e Excipients: Iris, NaCl, water for injection.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e Disposable.\u003cbr\u003e No case of hypersensitivity to MD-SHOULDER has been reported.\u003cbr\u003e Contains collagen of animal origin from porcine species.\u003cbr\u003e Patients with known hypersensitivity to the component or excipients must first undergo an injection test in the arm and be observed for one hour. \u003cbr\u003eShoulder pain requires differential diagnosis with chronic cervical syndrome, ischemic heart disease (acute\/chronic, left shoulder only), cholecystitis\/cholelithiasis (right shoulder only), cervico-brachialgia, trapezius muscle trigger point.\u003cbr\u003e Slight redness at the injection area may be due to the mechanical effect of the needle or a skin reaction.\u003cbr\u003e The application may cause burning\/pain symptoms at the injection sites, which generally resolve within 5-10 minutes after the end of treatment.\u003cbr\u003e Skin cleaning\/disinfection is required before and after application.\u003cbr\u003e Any pyogenic bacteria may produce an abscess in the injection area.\u003cbr\u003e Keep out of the reach and sight of children.\u003cbr\u003e Do not use after expiration.\u003cbr\u003e Use the product immediately after opening.\u003cbr\u003e Do not use if seal is broken or tampered with. \u003cbr\u003eAfter opening, the contents of the vial must be injected immediately.\u003cbr\u003e Do not use if packaging is damaged.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store at a temperature between 2°C and 30°C, protect from sunlight and frost.\u003cbr\u003e The expiry date refers to the product in its intact packaging, stored correctly.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack of 10 sterile 2 ml vials\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e MD10\u003c\/div\u003e","brand":"GUNA SPA","offers":[{"title":"Default Title","offer_id":52783839215950,"sku":"930010804","price":91.2,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/930010804.jpg?v=1768773731"},{"product_id":"md-tissue-5-flaconcini-iniettabili-2-ml","title":"MD-TISSUE 5 INJECTABLE VIALS 2 ML","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e MD-TISSUE\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Medical device useful for facilitating mobility, counteracting the physiological aging of connective tissue, whose primary therapeutic treatment consists of the following functions:\u003cbr\u003e 1. Barrier effect.\u003cbr\u003e 2. Lubricating activity.\u003cbr\u003e 3. Mechanical support in case of ongoing drug therapy.\u003cbr\u003e The use of MD-TISSUE by qualified healthcare personnel in private or public healthcare facilities is recommended for:\u003cbr\u003e - create a defense barrier against free radicals;\u003cbr\u003e - counteract the physiological aging of connective tissue;\u003cbr\u003e - relieve localized pain caused by movement.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e MD-TISSUE can be used alone or in combination with all other medical devices belonging to the same line, in order to create a personalized treatment based on the individual clinical picture. \u003cbr\u003eFor use in the treatment of facial and neck wrinkles and firming of the subcutaneous connective tissue layer, MD-TISSUE should preferably be combined with MD-MATRIX (e.g. MD-TISSUE 2 vials, MD-MATRIX 1 vial\/treatment).\u003cbr\u003e The device can be used in patients requiring collagen supplementation or topical anti-aging treatment.\u003cbr\u003e\u003cbr\u003e \u003cu\u003eTherapeutic protocol\u003c\/u\u003e :\u003cbr\u003e 2 treatments for the first 2 weeks, 1 treatment until symptoms improve (on average 8-10 sessions). If necessary, you can continue with 1 treatment every other week for a maximum of 10 sessions.\u003cbr\u003e Chronic conditions: continue with 1 treatment per week for one month until symptoms improve, and then with 1 treatment per month.\u003cbr\u003e\u003cbr\u003e • Intradermally: the application area must be aseptic; \u003cbr\u003e\u003ci\u003eMicroinjections\u003c\/i\u003e : insert the needle to a depth of 1-3 mm, perform microinjections of 0.2 ml – 0.3 ml in correspondence with the tissue to be treated.\u003cbr\u003e \u003ci\u003eTunneling\u003c\/i\u003e : 0.3 ml is applied along the wrinkle using the tunneling technique. Insert the needle almost tangentially along the entire length of the area, then inject and simultaneously withdraw the needle, while applying the product in a fan pattern.\u003cbr\u003e\u003cbr\u003e • Periarticularly: the application area must be aseptic, insert the needle perpendicularly to the skin plane to a depth of 2-4 mm, perform microinjections of 0.3-0.5 ml.\u003cbr\u003e\u003cbr\u003e \u003cu\u003eMethod of administration\u003c\/u\u003e :\u003cbr\u003e For this use of the medical device, the use of the following materials and accessories is recommended:\u003cbr\u003e • Material to ensure skin asepsis: disposable glove, iodine-based solution, alcohol solution, sterile gauze, ethyl chloride-based skin spray.\u003cbr\u003e • Microinjection needles: sterile 27 G, 4 mm. \u003cbr\u003e• Tunneling needles: sterile 30G, 13mm.\u003cbr\u003e • Syringes: 5 or 10 cc, depending on the quantity of solution to be injected.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Collagen of porcine origin.\u003cbr\u003e Excipients: ascorbic acid, magnesium gluconate, pyridoxine hydrochloride, riboflavin, thiamine hydrochloride, NaCl, water for injection.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e Disposable.\u003cbr\u003e No case of hypersensitivity has been reported.\u003cbr\u003e Contains collagen of animal origin from porcine species. Patients with known hypersensitivity to the component or excipients must first undergo an injection test in the arm and be kept under observation for one hour.\u003cbr\u003e Slight redness at the injection area may be due to the mechanical effect of the needle or a skin reaction.\u003cbr\u003e The application may cause burning\/pain symptoms at the injection sites, which generally resolve within 5-10 minutes after the end of treatment.\u003cbr\u003e Skin cleaning\/disinfection is required before and after application. \u003cbr\u003eAny pyogenic bacteria may produce an abscess in the injection area.\u003cbr\u003e Keep out of the reach and sight of children.\u003cbr\u003e Do not use after expiration.\u003cbr\u003e Use the product immediately after opening.\u003cbr\u003e Do not use if seal is broken or tampered with.\u003cbr\u003e After opening, the contents of the vial must be injected immediately.\u003cbr\u003e Do not use if packaging is damaged.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store at a temperature between 2°C and 30°C, protect from sunlight and frost.\u003cbr\u003e The expiry date refers to the product in its intact packaging, stored correctly.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack of 5 sterile 2 ml vials\u003c\/div\u003e","brand":"GUNA SPA","offers":[{"title":"Default Title","offer_id":52783861891406,"sku":"944118710","price":50.35,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/944118710.jpg?v=1768773976"},{"product_id":"siringa-intra-articolare-orthovisc-mini-acido-ialuronico-15-mg-1-ml-1-pezzo","title":"ORTHOVISC MINI INTRA-ARTICULAR SYRINGE HYALURONIC ACID 15 MG 1 ML 1 PIECE","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e ORTHOVISC\u003cbr\u003e ORTHOVISC\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e\n\n \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Medical device.\u003cbr\u003e Sodium hyaluronate for intra-articular injection. \u003cbr\u003eSodium hyaluronate is a high molecular weight polysaccharide composed of sodium glucuronate and N-acetylglucosamine. Sodium hyaluronate is distributed throughout the body and is present in high concentrations in tissues such as the vitreous humor, synovial fluid, umbilical cord, and dermis. Sodium hyaluronate acts as a tissue lubricant and is thought to play an important role in modulating the interaction between adjacent tissues and may act as a viscoelastic support by maintaining tissue separation. Different sodium hyaluronate preparations may have different molecular weights but are thought to have the same chemical structure.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e \u003cbr\u003eStore at 2° to 25°C. Allow to reach room temperature approximately 20-45 minutes before use. Not for intravenous injection. The required amount is slowly infused into the selected joint space through an ISO\/ANSI compliant, non-rigid, fulcrum hypodermic needle of appropriate diameter. Diameters used for knee injections are 18-21 gauge. The final selection for any procedure should be determined by the physician. The volume will vary depending on the size of the joint space but should not exceed 2 ml for the knee and other large joints or 1 ml for small joints. The physician should determine the appropriate volume to ensure that the joint is not overfilled. The recommended regimen is 3 injections at 1 week intervals for each treatment course, with a maximum treatment course for an individual joint in any 6 month period. Any effusion from the joint should be removed prior to injecting the product. Don't overfill the joint space. \u003cbr\u003e\u003cbr\u003e\u003cb\u003eContraindications\u003c\/b\u003e\u003cbr\u003e The following pre-existing conditions may constitute relative or absolute contraindications for the use of the products:\u003cbr\u003e – known sensitivity to any of the ingredients contained in the two products;\u003cbr\u003e – pre-existing infections of the skin region at the intended injection site;\u003cbr\u003e – known joint infections;\u003cbr\u003e – known systemic bleeding abnormalities.\u003cbr\u003e The products may contain traces of gram-positive bacterial proteins and are contraindicated in patients with a history of similar allergies.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e \u003cbr\u003eIt is recommended that the usual precautions for injections of substances into joints be taken. Only medical personnel competent in accepted injection techniques for the administration of agents into joint spaces should inject sodium hyaluronate for this application. Do not use excessive amounts of sodium hyaluronate and keep the patient under close observation. Do not overfill the space. If pain increases during the injection, stop the injection and withdraw the needle. In case of abnormal consequences to the administration of the products, patients should contact their physician immediately. Do not use if the inner package (pouch) is opened or damaged. For intra-articular injection. Not for intravenous injection. The sale and use of this medical device are restricted to a physician or under the supervision of a physician. Single use product. Do not resterilize.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e \u003cbr\u003eStore products at a temperature between 2°C and 25°C. Avoid freezing.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Orthosivisc: pack of 1 and 3 2 ml syringes.\u003cbr\u003e Orthosivisc mini (quantity for small joints): pack of 1 and 3 syringes of 1 ml.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCode\u003c\/b\u003e VROV1 \/ VROV3 \/ VR0M1 \/ VR0M3\u003c\/div\u003e","brand":"ALTAIR PHARMA SRL","offers":[{"title":"Default Title","offer_id":52809780461902,"sku":"912619499","price":57.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-091570.jpg?v=1768788581"},{"product_id":"md-hip-italia-10-flaconcini-2-ml","title":"MD-HIP ITALIA 10 VIALS 2 ML","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e MD-HIP\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Medical device useful for improving the mobility of the hip joint, whose primary therapeutic treatment consists of the following functions:\u003cbr\u003e 1. Barrier effect.\u003cbr\u003e 2. Lubricating activity.\u003cbr\u003e 3. Mechanical support in case of ongoing drug therapy.\u003cbr\u003e The use of MD-HIP by qualified healthcare personnel in private or public healthcare facilities is recommended for:\u003cbr\u003e - improve hip joint mobility;\u003cbr\u003e - promote muscle relaxation in the lumbar-sacral area;\u003cbr\u003e - support the periarticular muscle structures;\u003cbr\u003e - relieve localized pain, or pain caused by joint movement or postural defects.\u003cbr\u003e  \u003cbr\u003e\u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e MD-HIP can be used alone or in combination with other medical devices from the same line, in order to guarantee personalized treatment based on the individual clinical picture.\u003cbr\u003e In cases where supportive treatment is required for the onset of acute pain, MD-HIP can be combined with MD-NEURAL, MD-POLY and MD-MUSCLE (one or more of these).\u003cbr\u003e Furthermore, in cases where tissue matrix support therapy is required or a slowing down of physiological aging is necessary, MD-HIP can be combined with MD-MATRIX and MD-TISSUE.\u003cbr\u003e\u003cbr\u003e \u003cu\u003eTherapeutic protocol\u003c\/u\u003e\u003cbr\u003e 1 treatment per week for 10 consecutive weeks.\u003cbr\u003e\u003cbr\u003e Method of administration: periarticular injection (the application area must be aseptic; insert the needle to a depth of 6-8 mm).\u003cbr\u003e For this use of the medical device, the use of the following materials and accessories is recommended: \u003cbr\u003e• Material to ensure skin asepsis: disposable glove, iodine-based solution, alcohol solution, sterile gauze, ethyl chloride-based skin spray.\u003cbr\u003e • Needles: sterile 27 G.\u003cbr\u003e • Syringes: 5 or 10 cc, depending on the quantity of solution to be injected.\u003cbr\u003e\u003cbr\u003e Method of administration: intra-articular injection.\u003cbr\u003e For this use of the medical device, the use of the following materials and accessories is recommended:\u003cbr\u003e • Material to ensure skin asepsis: disposable glove, iodine-based solution, alcohol solution, sterile gauze, ethyl chloride-based skin spray. The application of a local anesthetic on the treated skin is recommended.\u003cbr\u003e • Needles: sterile 22 G.\u003cbr\u003e • Syringes: 2 cc, depending on the quantity of solution to be injected.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Collagen of porcine origin.\u003cbr\u003e Excipients: calcium phosphate, NaCl, water for injection.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e Disposable. \u003cbr\u003ePatients on anticoagulant therapy or with known capillary fragility should be kept under close observation during therapy.\u003cbr\u003e No case of hypersensitivity to MD-HIP has been reported.\u003cbr\u003e Contains collagen of animal origin from porcine species. Patients with known hypersensitivity to the component or excipients must first undergo an injection test in the arm and be kept under observation for one hour.\u003cbr\u003e Coxalgia requires differential diagnosis with pain secondary to primary or metastatic tumors, reflex neuralgia of lumbar origin, inguinal hernia.\u003cbr\u003e Slight redness at the injection area may be due to the mechanical effect of the needle or a skin reaction.\u003cbr\u003e The application may cause burning\/pain symptoms at the injection sites, which generally resolve within 5-10 minutes after the end of treatment.\u003cbr\u003e Skin cleaning\/disinfection is required before and after application. \u003cbr\u003eAny pyogenic bacteria may produce an abscess in the injection area.\u003cbr\u003e Keep out of the reach and sight of children.\u003cbr\u003e Do not use after expiration.\u003cbr\u003e Use the product immediately after opening.\u003cbr\u003e Do not use if seal is broken or tampered with.\u003cbr\u003e After opening, the contents of the vial must be injected immediately.\u003cbr\u003e Do not use if packaging is damaged.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store at a temperature between 2°C and 30°C, protect from sunlight and frost.\u003cbr\u003e The expiry date refers to the product in its intact packaging, stored correctly.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack of 10 sterile 2 ml vials\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e MD01\u003c\/div\u003e","brand":"GUNA SPA","offers":[{"title":"Default Title","offer_id":52809792389454,"sku":"930010057","price":91.2,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/930010057.jpg?v=1746498710"},{"product_id":"md-shoulder-5-flaconcini-da-2-ml","title":"MD-SHOULDER 5 VIALS OF 2 ML","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e MD-SHOULDER\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Medical device based on porcine collagen type I to reduce pain and improve joint mobility of the shoulder and upper limb.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e - Peri-articular route: insert the needle close to the joint to a minimum depth of 13-25 mm.\u003cbr\u003e - Intra-articularly: insert the needle below the lower margin of the posterior angle of the acromion, in the direction of the coracoid process.\u003cbr\u003e RECOMMENDED NEEDLES \u003cbr\u003e- Peri-articular: 26G x 25mm needle.\u003cbr\u003e - Intra-articular: 22G x 32 mm needle.\u003cbr\u003e Note: Perform thorough skin disinfection with povidone-iodine or chlorhexidine.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eTHERAPEUTIC PROTOCOL\u003c\/b\u003e\u003cbr\u003e 1-2 infiltrations per week to contain the physiological or pathological deterioration of the shoulder joint, elbow and surrounding tissues. Results are already evident from the third week but, depending on the patient's clinical situation, it is possible to continue the treatment until the tenth week without risks.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Porcine collagen, Iris versicolor, sodium chloride, water for injection.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e Shoulder pain requires differential diagnosis with chronic cervical syndrome, ischemic heart disease (acute\/chronic, left shoulder only), cholecystitis\/cholelithiasis (right shoulder only), cervico-brachialgia, trapezius muscle trigger point. \u003cbr\u003eSlight redness at the injection site may be due to the mechanical effect of the needle or a skin reaction. The application may cause burning\/pain symptoms at the injection sites, which generally resolve within 5-10 minutes after the end of treatment.\u003cbr\u003e Skin cleaning\/disinfection is required before and after application. Any pyogenic bacteria may produce abscess in the injection area.\u003cbr\u003e Keep out of the reach and sight of children.\u003cbr\u003e Do not use after the expiry date. The expiry date refers to the product in its intact packaging and stored correctly. Use the product immediately after opening.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack of 5 and 10 vials (2 ml each - extractable volume).\u003c\/div\u003e","brand":"GUNA SPA","offers":[{"title":"Default Title","offer_id":52818974671182,"sku":"941452815","price":50.35,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-272559.jpg?v=1768775935"},{"product_id":"md-small-joints-5-flaconcini-da-2-ml","title":"MD-SMALL JOINTS 5 VIALS OF 2 ML","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e MD-SMALL JOINTS\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Medical device based on type I porcine collagen to reduce pain and improve mobility of small joints (hand, foot, ankle).\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e - Peri-articular route: insert the needle close to the joint, parallel to the capsular plane, to a depth of 6-13 mm.\u003cbr\u003e - Intra-articular: insert the needle perpendicularly to the skin into small joints.\u003cbr\u003e RECOMMENDED NEEDLES\u003cbr\u003e Peri-articular: 26G x 13mm needle.\u003cbr\u003e Intramuscular: 20G x 20mm needle.\u003cbr\u003e Note: Perform thorough skin disinfection with povidone-iodine or chlorhexidine.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eTHERAPEUTIC PROTOCOL\u003c\/b\u003e \u003cbr\u003e1-2 infiltrations per week to contain the physiological or pathological deterioration of small joints and ligaments. Results already evident from the third week but, depending on the clinical situation of the patient, it is possible to continue the treatment until the tenth week without risks.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Porcine collagen, Viola odorata, sodium chloride, water for injection.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e Pain in the hands, feet and small joints requires differential diagnosis with primary neuralgia, post-traumatic pain, pain secondary to recent or previous bone fractures.\u003cbr\u003e Slight redness at the injection site may be due to the mechanical effect of the needle or a skin reaction. The application may cause burning\/pain symptoms at the injection sites, which generally resolve within 5-10 minutes after the end of treatment. \u003cbr\u003eSkin cleaning\/disinfection is required before and after application. Any pyogenic bacteria may produce abscesses in the injection area.\u003cbr\u003e Keep out of the reach and sight of children.\u003cbr\u003e Do not use after the expiry date. The expiry date refers to the product in its intact packaging and stored correctly. Use the product immediately after opening.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack of 5 and 10 vials (2 ml each - extractable volume).\u003c\/div\u003e","brand":"GUNA SPA","offers":[{"title":"Default Title","offer_id":52870295912782,"sku":"941452839","price":50.35,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-272561.jpg?v=1768777306"},{"product_id":"siringa-intra-articolare-kd-gel-acido-ialuronico-2-5-ultra-one-120-mg-4-8-ml","title":"INTRA-ARTICULAR SYRINGE KD HYALURONIC ACID GEL 2.5% ULTRA ONE 120 MG\/4.8 ML","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e \u003cfont face=\"arial\"\u003eKD Intra-articular Gel 2.5%\u003c\/font\u003e\n\u003c\/h1\u003e\n\u003ch3\u003e Ultra One 120mg\/4.8ml\u003c\/h3\u003e\n\u003cdiv align=\"justify\"\u003e KD Intra-articular Gel 2.5% Ultra One is a medical device with the CE mark in compliance with European Community directives.\u003cbr\u003e KD Intra-articular Gel is the innovative natural hyaluronic acid with very high concentration and high molecular weight.\u003cbr\u003e These characteristics allow for optimal visco-supplementation: the synovial fluid of the treated joint acquires greater viscoelasticity and a superior capacity to absorb shocks. \u003cbr\u003eThe pain of the joint treated with intra-articular KD Gel can decrease significantly and rapidly while the mobility of the treated joint tends to improve. In fact, the product can be effective on the pain and mobility of the treated joint already after the first cycle of intra-articular infiltration.\u003cbr\u003e It is indicated in case of pain and limitation of joint mobility, in case of degenerative and traumatic changes of the knee joint and other synovial joints.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e KD Gel Intra-articular 2.5% Ultra One must be injected only once every six months intra-articularly.\u003cbr\u003e Usually, just 1 injection is enough.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eIngredients\u003c\/b\u003e\u003cbr\u003e Medical device with CE marking containing 120 mg\/4.8 ml of linear hyaluronic acid obtained by fermentation and not chemically modified.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e \u003cbr\u003eThe advantages and benefits of a cycle of 1 intra-articular injection can last for at least 6 months; if necessary the cycle can be repeated.\u003cbr\u003e The opportunity and frequency with which the treatment cycle can be repeated must be evaluated by the doctor for each individual patient, considering in each case the risk\/benefit ratio of the treatment.\u003cbr\u003e Transparent, sterile, apyrogenic solution with viscoelastic properties.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e KD Intra-articular Gel 2.5% Ultra One must be stored in the original packaging at a temperature between 0°C and 25°C, protected from direct sunlight and frost.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack of 1 pre-filled syringe of 4.8 ml containing 120 mg of hyaluronic acid.\u003c\/div\u003e","brand":"LIFE MED SRLS","offers":[{"title":"Default Title","offer_id":52870297485646,"sku":"973350895","price":229.5,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-159588.jpg?v=1768777327"},{"product_id":"siringa-intra-articolare-innoryos-2-2-acido-ialuronico-2-ml","title":"INTRA-ARTICULAR SYRINGE INNORYOS 2.2% HYALURONIC ACID 2 ML","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e INNORYOS\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e \u003cbr\u003eThe product contains a pre-packaged injection of highly purified sodium hyaluronate hydrogel, obtained by bacterial fermentation with high molecular weight, useful for improving the viscosity of intra-articular connective tissue. It has been subjected to steam sterilization for injectable products and is not pyrogenic.\u003cbr\u003e One milliliter of aqueous, physiological phosphate buffer solution contains 16 mg, 22 mg or 25 mg of sodium hyaluronate, depending on the product variant and concentration. The hyaluronic acid hydrogel is in a weak, sterile, isotonic, pyrogen-free saline phosphate buffer solution with a pH of 7.2 (6.8 - 7.4) and a volume sufficient for injection. Filling volumes are 1 - 4.8 ml, depending on the variant. \u003cbr\u003eThe widely distributed glycosaminoglycan hyaluronic acid is a key component of healthy synovial fluid. This natural biopolymer ensures viscoelasticity and enables pain-free physiological movements due to its lubricating and cushioning properties; it also provides nutrients to the cartilage. The sodium hyaluronate contained in INNORYOS is a salt of hyaluronic acid.\u003cbr\u003e Pain and limited joint mobility in degenerative changes of the knee joint and other synovial joints, including osteoarthritis.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e \u003cbr\u003eThe pre-packaged syringe should be removed from its packaging. The protective cap should be removed from the Luer-Lock thread. Screw a suitable sterile injection needle onto the syringe. The use of a disposable needle is recommended. Before injection, the air should be removed from the syringe. The area of ​​skin intended for injection should be cleansed with an appropriate topical antiseptic product. In case of joint effusion, it is recommended to reduce the effusion by aspiration and to examine its bacterial etiology, before proceeding with the injection of INNORYOS. The hydrogel can be injected intra-articularly 1 to 5 times at intervals determined by the physician. The beneficial effects of a treatment last at least 6 months. Treatment cycles can be repeated if necessary.\u003cbr\u003e Depending on the filling volume, several joints of a patient can be treated simultaneously. Unused product should be discarded.\u003cbr\u003e \u003cbr\u003e\u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e The product cannot be applied to patients with:\u003cbr\u003e - a known sensitivity to one of the components;\u003cbr\u003e - an inflammation of the joint;\u003cbr\u003e - septic arthritis;\u003cbr\u003e - skin infections or skin diseases at the injection site;\u003cbr\u003e - natural or pharmacological reduction of coagulation such as haemophilia or in anticoagulant therapy such as Marcumar (phenprocoumon) or Coumadin (warfarin).\u003cbr\u003e Since there are no clinical data available on the use of hyaluronic acid in children, pregnant or breastfeeding women, its use is not recommended for these categories of people. \u003cbr\u003eSince septic arthritis can be a serious side effect of treatment, please observe all precautionary measures typical of surgical interventions. Hydrogel injections must be made exactly into the knee cavity; injections into blood vessels and adjacent tissue should be avoided. Do not use if the pre-packaged syringe or sterile packaging is damaged. The opened product cannot be re-sterilized, resealed or reused. Use is reserved for a single patient in a single application session. \u003cbr\u003eLocal symptoms such as pain, redness, heat and swelling may occur at the treated joint. These symptoms can be avoided by cooling the treated area with an ice pack for about 5 - 10 minutes after the injection. During the first few days of treatment, it may be helpful to take oral painkillers and anti-inflammatory drugs (NSAIDs). In the event of intense redness or inflammation, treatment should be stopped. Treatment of adverse reactions should be done only under the supervision of your doctor. Immediately after the injection, you should avoid intense physical activity and follow your doctor's instructions.\u003cbr\u003e Medical personnel must inform the patient:\u003cbr\u003e - on possible adverse events related to the product;\u003cbr\u003e - that the patient should report any adverse events or complications to a physician.\u003cbr\u003e The product must be kept out of reach of children.\u003cbr\u003e For use by physicians only. \u003cbr\u003eSingle use only. Do not re-sterilize. Do not use syringes, needles, and hydrogel from opened or damaged packages, and do not attempt to reseal packages.\u003cbr\u003e The contents of the syringe are non-toxic and non-flammable.\u003cbr\u003e If a product is used from a damaged package or if it is reused for other patients or for the same patient at another time, the intended properties and sterility are not ensured. In the event of non-compliance, the possible transmission of contaminated material and pathogens from the environment, the clinical environment or (other) patients could lead to health complications. Reclosing or re-sterilizing does not represent any permitted or guaranteed reconstitution of the usable state. \u003cbr\u003eUnused syringes and their contents are non-infectious and can be disposed of both before and after their expiry date, in accordance with national and local regulations. Used syringes and needles should be considered as epidemiologically hazardous waste and disposed of in accordance with national and local regulations for safe use and disposal.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e The product must be stored in a dry place at a temperature between 2°C and 25°C, away from light and shock, in its original packaging. It is therefore necessary to respect the warning symbols on the packaging.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Case with 2 ml syringe.\u003c\/div\u003e","brand":"LIFE MED SRLS","offers":[{"title":"Default Title","offer_id":52901098127694,"sku":"984821405","price":117.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-261648.jpg?v=1768778146"},{"product_id":"md-neck-italia-10-fiale-iniettabili-da-2ml","title":"MD-NECK ITALIA 10 INJECTABLE VIALS OF 2ML","description":"\u003ch3\u003e Md-Neck Injectable Vials\u003c\/h3\u003e\n\n \u003cp\u003eMedical device available in vials of injectable solution, based on collagen of porcine origin\u003c\/p\u003e\n\n\u003cp\u003e Use by qualified healthcare personnel is recommended.\u003cbr\u003e Porcine collagen, Silicic acid, NaCl, Water for injection.\u003c\/p\u003e\n\n\u003cp\u003e Format\u003cbr\u003e 10 vials of 2 ml of solution for injection\u003c\/p\u003e","brand":"GUNA SPA","offers":[{"title":"Default Title","offer_id":52934810009934,"sku":"930010739","price":91.2,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-229087.jpg?v=1768778983"},{"product_id":"jonexa-up-siringa-intra-articolare-sodio-ialuronato-cross-linkato-2-4-4-ml","title":"JONEXA UP INTRA-ARTICULAR SYRINGE SODIUM HYALURONATE CROSS-LINKED 2% 4.4 ML","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e Jonexa UP\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Biocompatible hydrogel of cross-linked sodium hyaluronate obtained by biofermentation and highly purified, dissolved in a physiological and isotonic buffer. The product is an injectable hydrogel, sterile and apyrogenic, with a low level of endotoxins. \u003cbr\u003eJONEXA UP is formulated with highly purified sodium hyaluronate, quality salts compliant with the requirements reported in the Pharmacopoeia and water for injections.\u003cbr\u003e JONEXA UP reduces pain and increases the functionality of the affected joint.\u003cbr\u003e JONEXA UP provides a lubricating and shock-absorbing effect on the affected joint.\u003cbr\u003e JONEXA UP improves the patient's quality of life.\u003cbr\u003e JONEXA UP must be administered by intra-articular injection by a qualified physician following all rules regarding aseptic procedure and injection technique.\u003cbr\u003e JONEXA UP must be injected with a suitable sterile needle (18-21G needles are recommended).\u003cbr\u003e It is recommended that JONEXA UP be administered in a single session. The amount of product to be administered is at the discretion of the medical specialist. Discard any unused portion of the syringe.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e \u003cbr\u003eJONEXA UP should be injected into the joint into the synovial space of the knee, as a means of viscosupplementation for the synovial fluid, when the viscosity of the fluid is reduced due to the osteoarthritis process, in patients who have not responded adequately to conservative non-pharmacological therapy and simple analgesics.\u003cbr\u003e 1. Before the injection, the area to be treated must be thoroughly disinfected and the product must be brought to room temperature.\u003cbr\u003e 2. Open the sterile packaging and remove the syringe from inside.\u003cbr\u003e 3. Remove the cap from the tip of the syringe without touching it, to keep it sterile.\u003cbr\u003e 4. Attach a suitable sterile needle (18-21G needles are recommended) to the tip of the syringe.\u003cbr\u003e Make sure the needle is properly locked onto the syringe's Luer-lock adapter before using it.\u003cbr\u003e 5. Remove air from the syringe, if necessary. \u003cbr\u003e6. Inject into the joint into the synovial space of the affected knee, following aseptic injection procedures.\u003cbr\u003e 7. At the end of the treatment session, throw away the syringe and any remaining product.\u003cbr\u003e The amount of product to be administered is at the discretion of the specialist doctor, the recommended dose is 3-4 ml for each knee joint.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Cross-linked sodium hyaluronate 20 mg\/ml, disodium phosphate dodecahydrate 0.6 mg\/ml, sodium dihydrogen phosphate dihydrate 0.05 mg\/ml, sodium chloride 8 mg\/ml, water for injections qs\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e Do not administer JONEXA UP to patients with known hypersensitivity (allergy) to hyaluronic acid and\/or other components of the product.\u003cbr\u003e Do not administer JONEXA UP to patients with acute or chronic dermatological disorders or with inflammatory and\/or infectious skin problems.\u003cbr\u003e Do not administer JONEXA UP to patients with coagulation disorders and\/or undergoing treatment with anticoagulant drugs. \u003cbr\u003eJONEXA UP should not be administered to women who are pregnant or breastfeeding.\u003cbr\u003e JONEXA UP should not be administered to children.\u003cbr\u003e The use of JONEXA UP in any joint other than the knee and for other conditions has not been studied.\u003cbr\u003e JONEXA UP must be strictly injected into the intra-articular space following aseptic injection procedures.\u003cbr\u003e JONEXA UP must be administered with sterile Luer-lock needles.\u003cbr\u003e Do not inject into a blood vessel or surrounding tissue. To avoid pain after the injection, it is recommended to keep the local injection site still.\u003cbr\u003e The product should not be used if the packaging is damaged or broken.\u003cbr\u003e The product should not be used after the expiry date.\u003cbr\u003e The product is for single use only. Do not reuse; risk of infection.\u003cbr\u003e Do not resterilize, resterilization may affect the physical-chemical properties of the product and compromise its efficacy and safety. \u003cbr\u003eThe used syringe and needle must be thrown into a special container.\u003cbr\u003e Keep out of reach of children.\u003cbr\u003e Do not use with other products containing quaternary ammonium salts such as benzalkonium chloride or with any surgical material treated with these types of substances, as sodium hyaluronate may precipitate in their presence. In order to prevent any possible interaction, avoid co-administration with other intra-articular products.\u003cbr\u003e No interactions with other local anesthetics are known.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store between 5°C and 25°C. Protect from light and avoid freezing.\u003cbr\u003e Do not use after the date shown on the package.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e 4.4 ml syringe.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCode\u003c\/b\u003e 6801\u003c\/div\u003e","brand":"ABIOGEN PHARMA SPA","offers":[{"title":"Default Title","offer_id":52972590924110,"sku":"989021011","price":153.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-323222.jpg?v=1768780356"},{"product_id":"siringa-intra-articolare-kd-gel-2-2-acido-ialuronico-2-ml","title":"INTRA-ARTICULAR SYRINGE KD GEL 2.2% HYALURONIC ACID 2 ML","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e \u003cfont face=\"arial\"\u003eKD Intra-articular Gel 2.2%\u003c\/font\u003e\n\u003c\/h1\u003e\n\u003ch3\u003e Sodium hyaluronate 2.0 ml\u003c\/h3\u003e\n\u003cdiv align=\"justify\"\u003e KD Gel intra-articular 2.2% is a medical device with the CE mark in compliance with the European Community directives.\u003cbr\u003e KD Intra-articular Gel is the innovative natural hyaluronic acid with very high concentration and high molecular weight.\u003cbr\u003e These characteristics allow for optimal visco-supplementation: the synovial fluid of the treated joint acquires greater viscoelasticity and a superior capacity to absorb shocks.\u003cbr\u003e The pain of the joint treated with intra-articular KD Gel can decrease significantly and rapidly while the mobility of the treated joint tends to improve. In fact, the product can be effective on the pain and mobility of the treated joint already after the first cycle of intra-articular infiltration. \u003cbr\u003eIt is indicated in case of pain and limitation of joint mobility, in case of degenerative and traumatic changes of the knee joint and other synovial joints.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e KD Gel Intra-articular 2.2% should be injected once a week for three weeks intra-articularly.\u003cbr\u003e Generally, 3 injections are sufficient.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eIngredients\u003c\/b\u003e\u003cbr\u003e Medical device with CE marking containing 44 mg\/2 ml of linear hyaluronic acid obtained by fermentation and not chemically modified.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e The advantages and benefits of a cycle of 3 intra-articular injections can last for at least 6 months; if necessary the cycle can be repeated.\u003cbr\u003e The opportunity and frequency with which the treatment cycle can be repeated must be evaluated by the doctor for each individual patient, considering in each case the risk\/benefit ratio of the treatment.\u003cbr\u003e Transparent, sterile, apyrogenic solution with viscoelastic properties.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e \u003cbr\u003eKD Gel intra-articular 2.2% must be stored in the original packaging at a temperature between 0°C and 25°C, protected from direct sunlight and frost.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack of 1 pre-filled syringe of 2 ml containing 44 mg of hyaluronic acid.\u003c\/div\u003e","brand":"LIFE MED SRLS","offers":[{"title":"Default Title","offer_id":52990656741710,"sku":"970255434","price":80.75,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-159592_58599179-74e4-4365-891d-bf6e50b9b1cb.jpg?v=1768780954"},{"product_id":"siringa-intra-articolare-sinovial-32-acido-ialuronico-sale-sodico-1-6-32mg-2ml-2ml-ago-21-gauge","title":"INTRA-ARTICULAR SYRINGE SINOVIAL 32 HYALURONIC ACID SODIUM SALT 1.6% 32MG\/2ML 2ML + NEEDLE 21 GAUGE","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e SYNOVIAL 32 2 ml\u003c\/h1\u003e\n\u003ch2\u003e 1.6% 32 mg\/2 ml\u003c\/h2\u003e  \u003cdiv align=\"justify\"\u003e\n\u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Substitute for synovial fluid, which allows to restore the physiological and rheological properties of arthritic joints. This therapeutic action is explained by the particular characteristics of the hyaluronic acid used. The hyaluronic acid contained in SINOVIAL 32 2 ml, obtained by fermentation and not chemically modified, has excellent tolerability. By restoring the viscoelastic properties of the synovial fluid, SINOVIAL 32 2 ml reduces pain and restores joint and tendon mobility.\u003cbr\u003e SINOVIAL 32 2 ml acts only at the level of the area in which it is injected, without exerting any systemic action. The improvement is immediate: already after the first injection, the global WOMAC index decreases and starting from the third injection the decrease becomes statistically significant. \u003cbr\u003eIndicated in cases of acute and chronic tendinopathies and\/or associated with joint disability and in the tendon repair process, even following surgery. SINOVIAL 32 2 ml is a medical device designed to integrate the synovial fluid, allowing the physiological and rheological properties of arthritic joints and tendons to be restored. In the joint, SINOVIAL 32 2 ml reduces pain and promotes the recovery of associated joint and tendon mobility, acting only in the synovial cavity into which it is injected, without exerting any systemic action. Furthermore, SINOVIAL 32 2 ml, thanks to its lubricating and viscoelastic characteristics, acts at the level of the tendon sheath, where it improves tendon gliding (“Tendon gliding”) and the physiological healing\/repair processes, thus preventing the formation of adhesions in the post-operative period.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e \u003cbr\u003eAspirate any joint effusion before injecting.\u003cbr\u003e Carefully unscrew the syringe cap, holding the \"Luer Lock\" closure collar firmly between your fingers and taking special care to avoid contact with the opening. Insert the needle into the Luer Lock closure collar of the syringe (needle diameter between 18 and 22G) screwing it firmly, until you feel a slight pressure in order to ensure a watertight seal and prevent the leakage of liquid during administration, holding the \"Luer Lock\" closure collar firmly between your fingers.\u003cbr\u003e Inject SINOVIAL 32 2 ml at room temperature and under strict aseptic conditions, into the synovial space of the joint or into the tendon sheath\/peritendinous area, depending on the identified medical need.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e \u003cbr\u003e1.6% hyaluronic acid, highly purified sodium salt (molecular weight between 800 and 1,200 KDalton), sodium chloride, sodium phosphate, water for injections.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e SINOVIAL 32 2 ml can only be injected by a doctor.\u003cbr\u003e The contents of the pre-filled syringe are sterile.\u003cbr\u003e The syringe is packaged in a sealed blister. The outer surface of the syringe is not sterile.\u003cbr\u003e Do not use after the expiry date shown on the package.\u003cbr\u003e Do not use if packaging is opened or damaged.\u003cbr\u003e The injection site must be on healthy skin.\u003cbr\u003e Do not inject vascularly. Do not inject outside the joint cavity, into the synovial tissue or into the joint capsule. Do not administer in the presence of large intra-articular effusion.\u003cbr\u003e Do not re-sterilize. The device is intended for single use only. Do not reuse to avoid any risk of contamination. \u003cbr\u003eOnce opened it must be used immediately and discarded after use.\u003cbr\u003e Keep out of the reach and sight of children.\u003cbr\u003e After intra-articular or tendon synovial injection, advise the patient to avoid all intense physical activity and to resume normal activities only after a few days.\u003cbr\u003e The possible presence of an air bubble does not affect the characteristics of the product.\u003cbr\u003e Do not mix SINOVIAL 32 2 ml with disinfectants such as quaternary ammonium salts or chlorhexidine as a precipitate may form. \u003cbr\u003eExtra-articular infiltration of SINOVIAL 32 2 ml may cause local side effects. During the use of SINOVIAL 32 2 ml, symptoms such as pain, heat, redness or swelling may appear at the injection site. These secondary manifestations can be alleviated by applying ice to the treated area. They usually disappear after a short time. The physician must ensure that patients inform him of any side effects that occur after treatment.\u003cbr\u003e SINOVIAL 32 2 ml must not be injected if the joint is infected or severely inflamed or if the patient has a skin condition or infection in the area of ​​the injection site.\u003cbr\u003e The product should not be used in case of known hypersensitivity to sodium hyaluronate or other components.\u003cbr\u003e To date, no interactions between SINOVIAL 32 2 ml and other drugs are known. \u003cbr\u003eDo not mix with disinfectants such as quaternary ammonium salts or chlorhexidine as a precipitate may form.\u003cbr\u003e It should not be injected if the joint is infected or severely inflamed or if the patient has a skin condition or infection at the injection site. The product should not be used in case of known hypersensitivity to sodium hyaluronate or other components.\u003cbr\u003e SINOVIAL 32 2 ml can only be injected by a doctor.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store at room temperature and in any case below 25 °C and away from heat sources. Do not freeze.\u003cbr\u003e Validity with intact packaging: 36 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack of 1 pre-filled syringe (32.0 mg of hyaluronic acid sodium salt in 2 ml of buffered saline sodium chloride solution).\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e 6000001304\u003c\/div\u003e","brand":"IBSA FARMACEUTICI ITALIA SRL","offers":[{"title":"Default Title","offer_id":52996317970766,"sku":"930411121","price":62.61,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/930411121.jpg?v=1768781127"},{"product_id":"siringa-intra-articolare-sinogel-2-4-acido-ialuronico-1-6-condroitina-sodica-3ml-1-ago","title":"INTRA-ARTICULAR SYRINGE SINOGEL 2.4% HYALURONIC ACID + 1.6% SODIUM CHONDROITIN 3ML + 1 NEEDLE","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e SYNOGEL 3 ml\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Medical device consisting of a buffered physiological solution of highly purified hyaluronic acid, with high molecular weight, and sodium chondroitin of biotechnological origin. The hyaluronic acid used in the device is obtained by fermentation and has not undergone chemical modification processes. This results in excellent tolerability. \u003cbr\u003eWith its particular formula and its high concentration of glycosaminoglycans (GAG), it belongs to the latest generation of intra-articular treatments and is specifically designed for the viscosupplementation of large joints for which a large volume of solution is recommended, with a high concentration of hyaluronic acid, without a high viscosity. The chains of hyaluronic acid and those of sodium chondroitin present in the device, thanks to a specific and patented treatment of the solution, interact with each other giving the solution rheological characteristics such as to obtain viscosity values ​​lower than those of hyaluronic acid alone at the same concentration.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e We recommend 1 infiltration per treatment cycle.\u003cbr\u003e The opportunity and frequency with which the treatment cycle can be repeated must be evaluated by the doctor, considering in each case the risk-benefit ratio for each individual patient.\u003cbr\u003e  \u003cbr\u003eAspirate any joint effusion before injecting SINOGEL 3 ml. Carefully unscrew the syringe cap, holding the “luer lock” closure collar firmly between your fingers and paying particular attention to avoid contact with the opening. Insert the 21 G needle provided in the product package into the luer lock closure collar of the syringe (insert an appropriate needle) and screw it firmly until you feel a slight pressure, so as to ensure a watertight seal and prevent the liquid from leaking out during administration, holding the luer lock closure collar firmly between your fingers. Inject SINOGEL 3 ml at room temperature and under conditions of strict aseptic conditions.\u003cbr\u003e For viscosupplementation of hip osteoarthritis, it is recommended to perform the injection under ultrasound guidance.\u003cbr\u003e Inject SINOGEL 3 ml only into the synovial space.\u003cbr\u003e  \u003cbr\u003eAt the end of the treatment, the doctor must fill out and give the patient the implant card, which can be found on the first page of the instructions for use contained in the package.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Sodium hyaluronate 72 mg, sodium chondroitin 48 mg, sodium chloride 21 mg, sodium phosphate monobasic 0.135 mg, sodium phosphate dibasic 0.48 mg, water for injections qs 3.0 ml.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e The contents of the pre-filled syringe are sterile. The syringe is packaged in a sealed blister. The outer surface of the syringe is not sterile.\u003cbr\u003e Do not use the device after the expiry date shown on the package.\u003cbr\u003e Do not use the device if the packaging is open or damaged as sterility may be compromised.\u003cbr\u003e The injection site must be on healthy skin.\u003cbr\u003e Do not use in pregnant or breastfeeding women.\u003cbr\u003e Do not use in patients with autoimmune diseases. \u003cbr\u003eDo not inject vascularly. Do not inject outside the joint cavity, into the synovial tissue or into the joint capsule.\u003cbr\u003e Do not administer the device in the presence of large intra-articular effusion.\u003cbr\u003e Do not re-sterilize. The device is intended for single use only.\u003cbr\u003e Do not reuse to avoid any risk of contamination.\u003cbr\u003e SINOGEL 3 ml is indicated for adult patients.\u003cbr\u003e Keep out of the reach and sight of children.\u003cbr\u003e Do not use SINOGEL 3 ml in case of known hypersensitivity or allergies to the components of the product.\u003cbr\u003e After intra-articular injection, advise the patient to avoid all strenuous physical activity and to resume normal activities only after a few days.\u003cbr\u003e Protect from sunlight.\u003cbr\u003e The possible presence of an air bubble does not affect the characteristics of the product.\u003cbr\u003e Do not mix the device with disinfectants such as quaternary ammonium salts or chlorhexidine as a precipitate may form. \u003cbr\u003eIf you are undergoing therapy and\/or taking medications in conjunction with treatment, consult your doctor for further information.\u003cbr\u003e Extra-articular infiltration of SINOGEL 3 ml may cause local side effects. During the use of SINOGEL 3 ml, symptoms such as pain, heat, redness or swelling may appear at the injection site. These secondary manifestations can be alleviated by applying ice to the treated joint. They usually disappear after a short time. The physician must ensure that patients inform him of any side effects that occur after treatment.\u003cbr\u003e In case of accident, consult the Manufacturer or the competent authority.\u003cbr\u003e Follow the indicated dosage and in case of side effects related to an overdose, contact your doctor or the nearest hospital. \u003cbr\u003eSINOGEL 3 ml must not be injected if the joint is infected or severely inflamed or if the patient has a skin condition or infection at the injection site.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store at room temperature and in any case below 25 °C and away from heat sources. Do not freeze.\u003cbr\u003e Once opened, the device must be used immediately and discarded after use.\u003cbr\u003e Validity with intact packaging: 36 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e 1 x 3ml pre-filled syringe and 1 x 21G x 1 \u0026amp;frac12\" (0.8 x 40mm) needle.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e 6000001266\u003c\/div\u003e","brand":"IBSA FARMACEUTICI ITALIA SRL","offers":[{"title":"Default Title","offer_id":53019210875214,"sku":"982951446","price":190.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-240298.jpg?v=1768782002"},{"product_id":"siringa-intra-articolare-synolis-v-a-sodio-ialuronato-20-mg-sorbitolo-40-mg-2ml-1-pezzo","title":"INTRA-ARTICULAR SYRINGE SYNOLIS VA SODIUM HYALURONATE 20 MG + SORBITOL 40 MG 2ML 1 PIECE","description":"\u003ch1\u003e SYNOLIS \u003cfont size=\"8\"\u003eVA\u003c\/font\u003e\n\n\u003c\/h1\u003e \u003cb\u003eSODIUM HYALURONATE \u0026amp; SORBITOL VISCO ANTALCIC\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e CE Class III medical device.\u003cbr\u003e Synolis VA is indicated to reduce pain and improve mobility of the knee joint and other synovial joints affected by degenerative and traumatic changes. \u003cbr\u003eSynolis VA is a sterile, pyrogen-free, isotonic viscoelastic solution based on sodium hyaluronate dissolved in a buffered saline solution. The sodium hyaluronate contained in this intra-articular injectable medical device is obtained by bacterial fermentation, has a high concentration (2%) and a high molecular weight, with an average molecular weight of 2,000,000 Daltons in the sterilized solution. The high concentration and high molecular weight of sodium hyaluronate, combined with the presence of an excipient (sorbitol) that limits its degradation, and the viscoelastic solution's ability to lubricate joints and absorb shock, simulating the rheological properties of synovial fluid, determine the effectiveness of this product in the treatment of osteoarthritis. Synolis VA works by restoring the physiological and rheological properties of synovial fluid affected by osteoarthritis, allowing for a reduction in pain and related discomfort as well as improving joint mobility. \u003cbr\u003eSynolis VA comes in a 2 ml pre-filled glass syringe. The syringe is contained in a sterilized individual protective pouch. Two types of packaging are available: boxes of 1 or 3 syringes containing the directions for use and a package leaflet.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e Synolis VA must be injected into the joint by a physician specialized in intra-articular injections.\u003cbr\u003e Aspirate any spills before injecting Synolis.\u003cbr\u003e Synolis VA must be injected at room temperature.\u003cbr\u003e Perform strict asepsis at the injection site.\u003cbr\u003e Use a needle of appropriate length and size (18 to 21 G, 2” is recommended).\u003cbr\u003e Screw the needle firmly onto the luer lock fitting of the syringe.\u003cbr\u003e Inject only into the joint cavity.\u003cbr\u003e In cases of gonarthrosis, it is advisable to administer Synolis VA following a dosage regimen of 3 injections spaced one week apart.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eContraindications\u003c\/b\u003e\u003cbr\u003e Synolis VA must not: \u003cbr\u003e- To be used in patients with known hypersensitivity to sodium hyaluronate and\/or sorbitol.\u003cbr\u003e - Be used in patients with a history of autoimmune diseases or in the presence of an abnormal physiological state.\u003cbr\u003e - Be injected into a joint in the presence of venous or lymphatic stasis in the affected limb.\u003cbr\u003e - Be injected into a joint if there is infection or severe inflammation.\u003cbr\u003e - Be injected into patients with skin disease or infection at the injection site.\u003cbr\u003e - Be injected intravascularly.\u003cbr\u003e - Be injected outside the intra-articular cavity or into the synovial membrane.\u003cbr\u003e - To be injected in the presence of severe effusion in the joint.\u003cbr\u003e - To be injected into pregnant women and individuals under 18 years of age.\u003cbr\u003e\u003cbr\u003e \u003cb\u003ePrecautions for use\u003c\/b\u003e\u003cbr\u003e - Reuse of single-use devices carries the potential risk of infection in the patient or user. \u003cbr\u003e- The solution must be administered following strict aseptic procedures (disinfection of the skin near the injection site is necessary before administering the product).\u003cbr\u003e - The Synolis VA syringe must not be reused for other patients and\/or for repeated injections (single use); the product must not be sterilized.\u003cbr\u003e - Do not use after the expiration date.\u003cbr\u003e - Check the integrity of the single protective casing.\u003cbr\u003e - sterilized; otherwise, avoid using it.\u003cbr\u003e - The patient is advised to avoid any strenuous physical activity for at least 48 hours after the injection.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eIncompatibility\u003c\/b\u003e \u003cbr\u003eThere is a known incompatibility between sodium hyaluronate and quaternary ammonium salts such as benzalkonium chloride. Carefully avoid contact of Synolis VA with such products (as in the case of some disinfectants), or with medical-surgical materials treated with this type of product. Currently, no further information is available on the compatibility of Synolis VA with other products for intra-articular use.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eSide effects\u003c\/b\u003e\u003cbr\u003e Intra-articular injections of Synolis VA may cause temporary pain, swelling, and\/or effusion. These reactions generally resolve within a few days. Contact your doctor if these symptoms persist for more than a week or if any side effects occur. Your doctor will recommend appropriate treatment.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store at a temperature between 2°C and 25°C.\u003cbr\u003e Protect from light and frost.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e \u003cbr\u003ePack of 1 pre-filled syringe of 2 ml.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCE Mark Registration Number\u003c\/b\u003e\u003cbr\u003e 0120","brand":"APTISSEN ITALIA SRL","offers":[{"title":"Default Title","offer_id":53024665796942,"sku":"922545809","price":88.35,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-087296.jpg?v=1768782155"},{"product_id":"siringa-intra-articolare-sinovial-32-acido-ialuronico-sale-sodico-1-6-32mg-2ml-3-siringhe-x-2ml-3-aghi","title":"INTRA-ARTICULAR SYRINGE SINOVIAL 32 HYALURONIC ACID SODIUM SALT 1.6% 32MG\/2ML 3 SYRINGES X 2ML + 3 NEEDLES","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e SYNOVIAL 32 2 ml\u003c\/h1\u003e\n\u003ch2\u003e 1.6% 32 mg\/2 ml\u003c\/h2\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Substitute for synovial fluid, which allows to restore the physiological and rheological properties of arthritic joints. This therapeutic action is explained by the particular characteristics of the hyaluronic acid used. The hyaluronic acid contained in SINOVIAL 32 2 ml, obtained by fermentation and not chemically modified, has excellent tolerability. By restoring the viscoelastic properties of the synovial fluid, SINOVIAL 32 2 ml reduces pain and restores joint and tendon mobility. \u003cbr\u003eSINOVIAL 32 2 ml acts only at the level of the area in which it is injected, without exerting any systemic action. The improvement is immediate: already after the first injection, the global WOMAC index decreases and starting from the third injection the decrease becomes statistically significant. \u003cbr\u003eIndicated in cases of acute and chronic tendinopathies and\/or associated with joint disability and in the tendon repair process, even following surgery. SINOVIAL 32 2 ml is a medical device designed to integrate the synovial fluid, allowing the physiological and rheological properties of arthritic joints and tendons to be restored. In the joint, SINOVIAL 32 2 ml reduces pain and promotes the recovery of associated joint and tendon mobility, acting only in the synovial cavity into which it is injected, without exerting any systemic action. Furthermore, SINOVIAL 32 2 ml, thanks to its lubricating and viscoelastic characteristics, acts at the level of the tendon sheath, where it improves tendon gliding (“Tendon gliding”) and the physiological healing\/repair processes, thus preventing the formation of adhesions in the post-operative period.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e \u003cbr\u003eAspirate any joint effusion before injecting.\u003cbr\u003e Carefully unscrew the syringe cap, holding the \"Luer Lock\" closure collar firmly between your fingers and taking special care to avoid contact with the opening. Insert the needle into the Luer Lock closure collar of the syringe (needle diameter between 18 and 22G) screwing it firmly, until you feel a slight pressure in order to ensure a watertight seal and prevent the leakage of liquid during administration, holding the \"Luer Lock\" closure collar firmly between your fingers.\u003cbr\u003e Inject SINOVIAL 32 2 ml at room temperature and under strict aseptic conditions, into the synovial space of the joint or into the tendon sheath\/peritendinous area, depending on the identified medical need.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e \u003cbr\u003e1.6% hyaluronic acid, highly purified sodium salt (molecular weight between 800 and 1,200 KDalton), sodium chloride, sodium phosphate, water for injections.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e SINOVIAL 32 2 ml can only be injected by a doctor.\u003cbr\u003e The contents of the pre-filled syringe are sterile.\u003cbr\u003e The syringe is packaged in a sealed blister. The outer surface of the syringe is not sterile.\u003cbr\u003e Do not use after the expiry date shown on the package.\u003cbr\u003e Do not use if packaging is opened or damaged.\u003cbr\u003e The injection site must be on healthy skin.\u003cbr\u003e Do not inject vascularly. Do not inject outside the joint cavity, into the synovial tissue or into the joint capsule. Do not administer in the presence of large intra-articular effusion.\u003cbr\u003e Do not re-sterilize. The device is intended for single use only. Do not reuse to avoid any risk of contamination. \u003cbr\u003eOnce opened it must be used immediately and discarded after use.\u003cbr\u003e Keep out of the reach and sight of children.\u003cbr\u003e After intra-articular or tendon synovial injection, advise the patient to avoid all intense physical activity and to resume normal activities only after a few days.\u003cbr\u003e The possible presence of an air bubble does not affect the characteristics of the product.\u003cbr\u003e Do not mix SINOVIAL 32 2 ml with disinfectants such as quaternary ammonium salts or chlorhexidine as a precipitate may form. \u003cbr\u003eExtra-articular infiltration of SINOVIAL 32 2 ml may cause local side effects. During the use of SINOVIAL 32 2 ml, symptoms such as pain, heat, redness or swelling may appear at the injection site. These secondary manifestations can be alleviated by applying ice to the treated area. They usually disappear after a short time. The physician must ensure that patients inform him of any side effects that occur after treatment.\u003cbr\u003e SINOVIAL 32 2 ml must not be injected if the joint is infected or severely inflamed or if the patient has a skin condition or infection in the area of ​​the injection site.\u003cbr\u003e The product should not be used in case of known hypersensitivity to sodium hyaluronate or other components.\u003cbr\u003e To date, no interactions between SINOVIAL 32 2 ml and other drugs are known. \u003cbr\u003eDo not mix with disinfectants such as quaternary ammonium salts or chlorhexidine as a precipitate may form.\u003cbr\u003e It should not be injected if the joint is infected or severely inflamed or if the patient has a skin condition or infection at the injection site. The product should not be used in case of known hypersensitivity to sodium hyaluronate or other components.\u003cbr\u003e SINOVIAL 32 2 ml can only be injected by a doctor.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store at room temperature and in any case below 25 °C and away from heat sources. Do not freeze.\u003cbr\u003e Validity with intact packaging: 36 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Pack containing 3 pre-filled syringes (32.0 mg of hyaluronic acid sodium salt in 2 ml of buffered saline sodium chloride solution) and 3 needles.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e 6000001305\u003c\/div\u003e","brand":"IBSA FARMACEUTICI ITALIA SRL","offers":[{"title":"Default Title","offer_id":53024666747214,"sku":"930411145","price":166.16,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/930411145.jpg?v=1768782167"},{"product_id":"siringa-intra-articolare-syaloset-2000-acido-ialuronico-1-5-2-ml-1-pezzo","title":"INTRA-ARTICULAR SYRINGE SYALOSET 2000 HYALURONIC ACID 1.5% 2 ML 1 PIECE","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e Syaloset 2000\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e \u003cbr\u003eSterile, apyrogenic, viscoelastic solution produced with hyaluronic acid sodium salt, obtained by bacterial fermentation from a high molecular weight fraction (\u0026lt;2.00 kDa). Hyaluronic acid is naturally present in many human tissues such as cartilage and synovial fluid: it is continuously secreted into the joint cavity and represents the major component of the synovial fluid to which it provides its characteristic viscosity and elasticity. These properties are essential for the fluid to perform the functions of lubricant and shock absorber in normal joints, in order to protect the cartilage and soft tissues from mechanical damage. \u003cbr\u003eTemporary substitute for synovial fluid indicated in the treatment of pain and reduced mobility in patients with degenerative or traumatic arthropathy of the synovial joints. The product acts by providing lubrication and mechanical support and is particularly suitable for the treatment of OA symptoms.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e Using a suitable sterile needle (e.g. 18 or 20 G), into the injured joint at weekly intervals for a total of 3 weeks. If necessary, additional injections may be performed. The administration of the product should be performed only by medical specialists. All rules regarding asepsis and infectious techniques must be observed. If an effusion is present, remove it before injecting the product.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Hyaluronic acid sodium salt 1.5%; other ingredients: sodium chloride, dibasic sodium phosphate 2H2O, water for injections.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e \u003cbr\u003eDo not use if the package is damaged. Keep out of the reach and sight of children. The contents of the pre-filled syringe are sterile. The external surface of the syringe is not sterile, but has a reduced bacterial load. It has not been tested in pregnant women. Do not use the product after the expiry date. Single use only.\u003cbr\u003e Do not use in conjunction with disinfectants containing quaternary ammonium salts, because hyaluronic acid may precipitate in their presence. Avoid the simultaneous administration of SYALOSET 2,000 with other products for intra-articular use, in order to prevent any possible interaction.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store at a temperature not exceeding 25 °C in the original container and do not expose to light.\u003cbr\u003e Do not freeze.\u003cbr\u003e The expiry date refers to the product stored in its original packaging at a temperature not exceeding 25 °C.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e 1 single-use pre-filled syringe of 30 mg\/2 ml.\u003c\/div\u003e","brand":"BIONATIVA SPA","offers":[{"title":"Default Title","offer_id":53024673005902,"sku":"970978211","price":61.66,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/970978211.jpg?v=1768782254"},{"product_id":"siringa-preriempita-intra-articolare-supartz-acido-ialuronico-25-mg-2-5-ml-5-pezzi","title":"PRE-FILLED INTRA-ARTICULAR SYRINGE SUPARTZ HYALURONIC ACID 25 MG 2.5 ML 5 PIECES","description":"\u003ch1\u003eSupartz\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e\n\n \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e SUPARTZ is a sterile, non-pyrogenic, highly purified, non-inflammatory, high molecular weight sodium hyaluronate solution extracted by bacterial fermentation and is a polysaccharide containing repeating disaccharide units of D-glucuronic acid and N-acetyl-D-glucosamine.\u003cbr\u003e Sodium hyaluronate is a common component of the extracellular matrices of connective tissues. It is found in many different species, including humans, but is chemically identical regardless of its species of origin.\u003cbr\u003e The sodium hyaluronate used in the manufacture of SUPARTZ is of bacterial origin and is derived through fermentation and purification.\u003cbr\u003e SUPARTZ is a clear, odorless solution with a pH of 6.8 to 7.8 and an osmotic pressure to saline ratio of 1.0 to 1.2. \u003cbr\u003eAfter injection into the joint, SUPARTZ is poorly metabolized in the synovial fluid, but is incorporated into the synovial tissues where it is partially degraded into smaller molecules. SUPARTZ then enters the bloodstream and is metabolized primarily in the liver. The metabolites are non-toxic and are permanently eliminated from the body through the lungs, intestines, and urinary tract.\u003cbr\u003e SUPARTZ is marketed as a sterile solution in a pre-filled disposable syringe to reduce the risk of contamination during aspiration of the solution.\u003cbr\u003e SUPARTZ is indicated for the treatment of knee OA and shoulder periarthritis, and is intended to improve joint motion by supplementing the viscoelasticity of synovial fluid, and to reduce pain in knee OA and shoulder periarthritis.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e \u003cbr\u003eThe dosage is 2.5 mL (one syringe) per knee joint injected intra-articularly or into the shoulder joint (shoulder socket, subacromial bursa, or tendon sheath of the long head of the biceps brachii).\u003cbr\u003e The recommended treatment regimen for SUPARTZ in adults consists of five injections into the knee joint cavity or shoulder joint (joint cavity, subacromial bursa, or biceps tendon sheath), at intervals of one injection per week. However, the timing of injections may be adjusted based on the patient's symptoms.\u003cbr\u003e SUPARTZ must be injected only by authorised medical personnel or in accordance with local legislation.\u003cbr\u003e No additional training is required.\u003cbr\u003e Check the expiry date on the package.\u003cbr\u003e Do not use after the expiration date.\u003cbr\u003e Strictly observe aseptic administration techniques. \u003cbr\u003eAspirate any joint effusion using a 22-23 gauge needle before injecting SUPARTZ. Maintain the needle position in the joint while removing the syringe used to reduce the joint effusion. Discard the syringe containing the aspirated joint effusion. Do not use the same syringe to aspirate the effusion and inject SUPARTZ.\u003cbr\u003e Subcutaneous injection of lidocaine or similar local anaesthetics may be performed prior to injection of SUPARTZ.\u003cbr\u003e Peel the Tyvek sheet from the blister and remove the syringe.\u003cbr\u003e Carefully remove the syringe cap and aseptically attach the syringe to a 22-23G needle. To ensure a tight seal and prevent leaks during administration (or injection), secure the needle by holding the luer lock firmly.\u003cbr\u003e If the effusion has been previously aspirated, connect the syringe to the needle already placed in the joint. \u003cbr\u003eUnscrew the cap before removing it to minimize product spillage.\u003cbr\u003e Inject SUPARTZ into the knee joint or shoulder joint (shoulder socket, subacromial bursa, or tendon sheath of the long head of the biceps brachii) through the needle using an aseptic injection technique.\u003cbr\u003e Inject the entire contents, 2.5 mL of SUPARTZ, into the knee or shoulder (shoulder socket, subacromial bursa, or biceps tendon sheath). If administering to both knees or shoulders, use a separate syringe of SUPARTZ for each knee or shoulder.\u003cbr\u003e To inject into the knee joint, insert the needle horizontally or at a slight downward angle into the joint space between the kneecap and the femur. It's not unusual to feel some resistance as the needle enters the joint capsule. \u003cbr\u003eIn the scapulohumeral joint, the needle is usually inserted most easily from the anterior side, but a posterior or lateral approach is also used.\u003cbr\u003e For accurate administration of SUPARTZ into the biceps sheath, insert the needle into the epidermis at a 20-30 degree angle and parallel to the biceps sheath. If the needle penetrates the tendon, resistance to the injection will occur. If available, perform an ultrasound-guided injection into the biceps sheath to more accurately identify the location.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e 2.5 ml of 1% sodium hyaluronate solution.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e - Do not administer SUPARTZ to patients with known hypersensitivity (allergy) to SUPARTZ or sodium hyaluronate preparations.\u003cbr\u003e - Extreme caution should be exercised when administering SUPARTZ to patients with infections or skin lesions at the injection site.\u003cbr\u003e - Administer SUPARTZ with caution in patients with hypersensitivity to any medicinal product. \u003cbr\u003e- Administer SUPARTZ with caution in patients with a history of liver dysfunction.\u003cbr\u003e - Administer SUPARTZ with caution in patients with systemic coagulopathies.\u003cbr\u003e - Administer SUPARTZ with caution to patients with lymphatic or venous stasis in the injected limb.\u003cbr\u003e - Do not use disinfectants containing quaternary ammonium salts (such as benzalkonium chloride) for skin preparation simultaneously, as sodium hyaluronate may precipitate in their presence. The use of disinfectants such as povidone-iodine is recommended.\u003cbr\u003e - Do not inject SUPARTZ intravascularly.\u003cbr\u003e - Strictly observe aseptic administration techniques.\u003cbr\u003e - Aspirate any joint effusion before injecting SUPARTZ.\u003cbr\u003e - The safety and performance of SUPARTZ have not been established in joints other than the knee or shoulder and for diseases other than OA. \u003cbr\u003e- The safety and performance of SUPARTZ in combination with other intra-articular injectable solutions have not been established.\u003cbr\u003e - The safety and efficacy of SUPARTZ in severely inflamed knee joints have not been established.\u003cbr\u003e - Do not inject SUPARTZ extra-articularly or into the synovial membrane and capsule.\u003cbr\u003e - STERILE CONTENTS. The pre-filled syringe is for single use only. The contents of the syringe must be used immediately after opening the package. Discard any unused SUPARTZ.\u003cbr\u003e - Do not use SUPARTZ if the blister is open or damaged or if there are cracks or breaks in the pre-filled syringe.\u003cbr\u003e - In osteoarthritic knees with severe inflammation, the inflammation should be reduced before injecting SUPARTZ, as the inflammation may be aggravated by the injection.\u003cbr\u003e - Use SUPARTZ by the expiry date indicated on the package. \u003cbr\u003e- As with any invasive joint procedure, the patient is advised to avoid any strenuous activity (such as jogging, tennis or other active sports, heavy work) and prolonged weight-bearing activities (such as standing for more than one hour) for 48 hours following treatment with intra-articular injection of SUPARTZ.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e The expiry date is indicated on the label and on the outer packaging.\u003cbr\u003e Store in the original packaging at a temperature of 1°C-25°C.\u003cbr\u003e Don't conglate.\u003cbr\u003e Shelf life when packaging is intact: 36 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e 5 pre-filled syringes 2.5 ml.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e MD030801\u003c\/div\u003e","brand":"MDM SPA","offers":[{"title":"Default Title","offer_id":53031507427662,"sku":"943008589","price":169.2,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/TE009-333929.jpg?v=1768782436"},{"product_id":"md-tissue-italia-10-flaconcini-iniettabili-2-ml","title":"MD-TISSUE ITALIA 10 INJECTABLE VIALS 2 ML","description":"\u003cb\u003eDescriptive sheet\u003c\/b\u003e\u003cbr\u003e\u003ch1\u003e GUN\u003cbr\u003e MD-TISSUE\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Collagen-based medical device.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e \u003cbr\u003ePack of 10 2 ml bottles.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e MD13\u003c\/div\u003e","brand":"GUNA SPA","offers":[{"title":"Default Title","offer_id":53038417707342,"sku":"930010905","price":91.2,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/930010905.jpg?v=1768782582"}],"url":"https:\/\/farmaspeed.it\/en-eu\/collections\/ortopedia.oembed","provider":"Farmaspeed","version":"1.0","type":"link"}