{"product_id":"hyalubrix-sir-30mg-2ml-3pz-n-e","title":"INTRA-ARTICULAR SYRINGE HYALUBRIX HYALURONIC ACID 1.5% 30 MG 2 ML 3 PIECES NO ETO","description":"\u003ch1\u003e HYALUBRIX\u003c\/h1\u003e\n\u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Sterile viscoelastic solution produced with hyaluronic acid sodium salt obtained by bacterial fermentation from a high molecular weight fraction. \u003cbr\u003eHyaluronic acid, a polysaccharide from the glycosaminoglycan family, is naturally present in many human tissues, such as cartilage and synovial fluid. It is continuously secreted into the joint cavity and is the major component of synovial fluid, providing it with its characteristic viscosity and elasticity. These properties are essential for the fluid's function as a lubricant and shock absorber in normal joints, protecting cartilage and soft tissue from mechanical damage.\u003cbr\u003e In traumatic and degenerative joint diseases, the amount of hyaluronic acid decreases and the synovial fluid loses viscosity, causing impaired function and painful symptoms. Many studies indicate that intra-articular administration of hyaluronic acid can restore the viscoelastic properties of the synovial fluid. \u003cbr\u003eHYALUBRIX is a treatment for the temporary replacement of synovial fluid in patients with degenerative or mechanical joint disease, which causes an alteration in the functional performance of the synovial fluid. Intra-articular injection of HYALUBRIX at weekly intervals reduces pain symptoms and improves joint function in patients with degenerative or mechanical joint disease for up to six months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e Intended for intra-articular injection only.\u003cbr\u003e The product must be administered exclusively by specialized doctors (e.g. orthopedic surgeon, rheumatologist, physiatrist radiologist, sports doctor, etc.).\u003cbr\u003e The injection must be strictly intra-articular. Intra-articular injections must be performed according to standard technique, using a precise anatomical location. In the hip, shoulder, and other less easily accessible joints, ultrasound or radioscopic guidance is recommended. \u003cbr\u003eAll rules regarding asepsis and injection techniques must be observed.\u003cbr\u003e Remove any joint effusions, if present, before administration. Attach a suitable sterile needle to the syringe (e.g., 18 or 20 gauge) and inject HYALUBRIX into the affected joint at weekly intervals for 3 weeks.\u003cbr\u003e If necessary, further cycles of injections may be performed, although systematic collection of clinical data is not available.\u003cbr\u003e Clinical data demonstrate the efficacy of HYALUBRIX for up to 6 months, however, if clinically required, the administration cycle can be repeated starting 3 months after the first treatment cycle.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Main component: hyaluronic acid sodium salt 1.5%.\u003cbr\u003e Other ingredients: sodium chloride, disodium phosphate 12H \u003csub\u003e2\u003c\/sub\u003e O, monosodium phosphate 2H \u003csub\u003e2\u003c\/sub\u003e O, water for injections.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e \u003cbr\u003eDo not administer to patients with known individual sensitivity to the product components.\u003cbr\u003e Do not administer if you have infections or skin diseases in the injection area.\u003cbr\u003e Do not administer to patients with active synovitis. \u003cbr\u003eThe safety and efficacy of HYALUBRIX in pregnant women, breastfeeding women, or individuals under 18 years of age have not been established and therefore its use is contraindicated in these patient populations. Do not use if the package is damaged. Do not use the product after the expiration date shown on the package. The expiration date refers to the product stored in its original packaging. The syringe is for single use only, meaning it should be used once and on a single patient. Inject the contents into one joint only. For the first 24 hours after the injection, the patient is permitted to continue all routine daily activities, but it is recommended not to overload the treated joint. The syringe complete with needle must be discarded immediately after use, even if the solution has not been completely administered. If the product is reprocessed and\/or reused, Fidia Farmaceutici cannot guarantee its performance, functionality, material structure, cleanliness, or sterility. Reuse may cause illness, infection, and\/or harm to the patient or user. Dispose of after use according to applicable regulations. Keep out of reach of children. \u003cbr\u003eLocalized pain, swelling, heat, and redness may occasionally occur at the injection site. These symptoms are generally mild and transient. After intra-articular injection, applying an ice pack to the treated joint for five to ten minutes will reduce the incidence of these events. Local or systemic allergic reactions may occur in individuals with hypersensitivity to the product's components. More marked inflammatory reactions, sometimes with the presence of sodium pyrophosphate crystals, have occasionally been reported in association with intra-articular injections of hyaluronate. As with any intra-articular treatment, septic arthritis may rarely occur if general injection precautions are not observed or the injection site is not aseptic. \u003cbr\u003eDo not use concomitantly with disinfectants containing quaternary ammonium salts, as hyaluronic acid may precipitate in their presence. Avoid concomitant administration of HYALUBRIX with other products for intra-articular use to prevent any possible interactions.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eConservation\u003c\/b\u003e\u003cbr\u003e Store below 25°C.\u003cbr\u003e Shelf life when packaging is intact: 18 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e Case containing 3 pre-filled syringes.\u003cbr\u003e The syringe is sealed in an ethylene oxide sterilized blister and contains 30 mg of hyaluronic acid sodium salt in 2 ml of steam sterilized solution.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e 10000951\u003c\/div\u003e","brand":"FIDIA FARMACEUTICI SPA","offers":[{"title":"Default Title","offer_id":50734433960270,"sku":"984515460","price":129.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/6214\/9710\/files\/984515460-1.jpg?v=1776905103","url":"https:\/\/farmaspeed.it\/en-eu\/products\/hyalubrix-sir-30mg-2ml-3pz-n-e","provider":"Farmaspeed","version":"1.0","type":"link"}