Name
AMFLEE COMBO 50 MG/60 MG SPOT-ON SOLUTION FOR CATS AND FERRETS

Category
Ectoparasiticides, insecticides and repellents.

Active ingredients
Each 0.5 ml pipette contains the active substances: fipronil 50 mg; S-Methoprene 60 mg.

Directions
Cat. For use against flea infestations, alone or in combination with ticks and/or biting lice: Treatment of flea infestations (Ctenocephalides spp.). Insecticidal efficacy against new infestations with adult fleas persists for 4 weeks. Prevention of flea multiplication by inhibiting the development of eggs (ovicidal activity), larvae, and pupae (larvicidal activity) from eggs laid by adult fleas for six weeks after application; Treatment of tick infestations (Ixodes ricinus, Dermacentor variabilis, Rhipicephalus sanguineus). The veterinary medicinal product has persistent acaricidal efficacy against ticks for up to 2 weeks; Treatment of biting lice (Felicola subrostratus) infestations. The veterinary medicinal product can be used as part of a treatment strategy for the control of Flea Allergy Dermatitis (FAD), where previously diagnosed by a veterinarian. Ferrets. For use against flea infestations, alone or in combination with ticks: Treatment of flea infestations (Ctenocephalides spp.). Insecticidal efficacy against new infestations with adult fleas persists for 4 weeks. Prevention of flea multiplication by inhibiting the development of eggs (ovicidal activity), larvae, and pupae (larvicidal activity) from eggs laid by adult fleas; Treatment of tick infestations (Ixodes ricinus). The veterinary medicinal product has persistent acaricidal efficacy against ticks for 4 weeks.

Dosage
For external use only, spot-on use. One 0.5 ml pipette per cat, corresponding to the minimum recommended dose of 5 mg/kg fipronil and 6 mg/kg S-methoprene, for topical administration to the skin. In the absence of safety studies, the minimum treatment interval is 4 weeks. One 0.5 ml pipette per ferret, corresponding to a recommended dose of 50 mg/kg fipronil and 60 mg/kg S-methoprene, for topical administration to the skin. The minimum treatment interval is 4 weeks. Directions for use: 1- Remove the pipette from the pouch. Hold the pipette upright, twist, and remove the cap. 2- Turn the cap upside down and replace it on the other end of the pipette. Press and twist the cap to break the seal, then remove the cap from the pipette. 3- Part the animal's fur on the back at the base of the neck in front of the shoulder blades until the skin is visible. Place the tip of the pipette on the skin and squeeze the pipette several times to empty the contents completely and directly onto the skin in one spot.

Conservation
Store in the original package to protect from light and moisture. This veterinary medicinal product does not require any special temperature storage conditions. Shelf life of the veterinary medicinal product as packaged for sale: 2 years.

Pregnancy and breastfeeding
Pregnancy. Cats: Laboratory studies in cats have shown no evidence of teratogenic, fetotoxic, or maternotoxic effects. The veterinary medicinal product can be used during pregnancy. Ferrets: The safety of the veterinary medicinal product has not been established in pregnant ferrets. Use only according to the benefit-risk assessment by the responsible veterinarian. Lactation. Cats: The potential toxicity of the veterinary medicinal product in kittens under 8 weeks of age in contact with treated adults has not been documented. Particular caution should be exercised in this case. Ferrets: The safety of the veterinary medicinal product has not been established during lactation. Use only according to the benefit-risk assessment by the responsible veterinarian.