Name
FRONTLINE SPRAY (FIPRONIL 0.25%)

Category
Topical ectoparasiticides, including insecticides.

Active ingredients
Active ingredient: fipronil 0.25 g. Excipients: isopropanol 80 ml; copolyvidone 2 g; deionized water qs to 100 ml.

Directions
Treatment and prevention of tick, flea and lice infestations in dogs and cats 2 days or older. Fipronil rapidly exerts its lethal action on ticks, preventing the development of the parasite and the possible transmission of infections carried by the tick. It is active against the main tick species present in the country, including Ixodes ricinus, responsible for the transmission of Lyme disease to dogs, cats and humans. Fipronil acts on fleas by rapidly killing the adult forms, thus preventing the deposition of eggs and therefore new infestations. Thanks to its lethal action on adult fleas, fipronil effectively contributes to the control and resolution of Flea Allergic Dermatitis (FAD) which, in dogs and cats, is caused by the sensitizing action exerted by the antigens contained in the saliva of these parasites. Fipronil also, with a single treatment, rapidly and definitively controls and resolves lice infestations in dogs and cats, in particular those caused by Trichodectes canis, the dog chewing louse, and by Felicola subrostratus, the cat chewing louse.

Dosage
Dosage: depending on the length of the hair, spray 3 to 6 ml of product/kg of weight. This volume corresponds to: 2-4 sprays/kg of weight, if using the 250 ml or 500 ml bottle (1 spray equals 1.5 ml); 6-12 sprays/kg of weight, if using the 100 ml bottle (1 spray equals 0.5 ml). Spray "against the grain" over the entire surface of the animal's body, from a distance of 10-20 cm, holding the bottle in a vertical position. Spray evenly, so as to uniformly "wet" the hair of the entire body. After spraying, carefully rub the back, shoulders, sides, abdomen, paws and neck to bring the product into direct contact with the skin. For the head and the area around the eyes, apply the product to a glove and pass it delicately "against the grain" on these parts. After these operations, leave to dry naturally. A single application of the product protects the animal from new infestations by ticks, fleas and lice, in particular from ticks: up to 1 month after treatment in both dogs and cats; from fleas: * up to 3 months after treatment in dogs. * up to 5 weeks after treatment in cats. For correct ectoparasitic prevention, it is advisable to carry out monthly treatments during the periods of greatest seasonality. In the absence of data on safety, the minimum treatment interval must be 4 weeks.

Conservation
Store in a cool, dry place away from flames or heat sources. Shelf life: 36 months.

Pregnancy and breastfeeding
The product can be used in bitches and cats during pregnancy and lactation. Frontline Spray is well tolerated by puppies and kittens, after treatment of mothers during lactation. Puppies and kittens of 2 days of age can be treated without any risk.