PROSENAL COMPLEX 60 TABLETS

Prosenal Complex

Packaging: 60 tablets of 450 mg
Recommended dosage: 1 tablet per day

Product based on Silicon, Phytoestrogens, Vitamin D3, Vitamin K2, which can be useful for the trophism of bone tissue.

Composition

Silicon
The dry extract of Bamboo stems and leaves contains high quantities of Silicon in organic form that is bioavailable and therefore easily assimilated. In our body, Silicon is a microelement present in connective tissues, bones, as a constituent of keratin and therefore of hair and nails. Silicon plays a structural role in the mineralization processes of bone tissue, in the synthesis of collagen and connective tissue. A deficiency can cause a reduction in body growth and a delay in development, a weakening and loss of elasticity of cartilage. The presence of an adequate quantity of Silicon in the body ensures the normal and physiological synthesis of both cartilage and bone tissue. The use of dietary supplementation of Silicon can therefore constitute both a preventive and curative treatment especially in alterations of bone mass, as it facilitates the absorption and deposition of calcium in the bones, improving their formation, consistency and density and also exerts an anti-resorptive action on osteoclasts.

Phytoestrogens
The e.s. of Soy Glycine (tit. 40% Isoflavones) present in the Prosenal Complex are compounds belonging to the category of phytoestrogens, substances of vegetal origin structurally and functionally similar to the estrogen hormones produced by the body. At the level of bone tissue, phytoestrogens exert an anti-resorptive and normo-regularizing activity as they promote the formation and density of bone mass by significantly inhibiting reabsorption.

Vitamin D3
The two main forms in which Vitamin D can be found, both with very similar biological activity, are Vitamin D2 (ergocalciferol), which is formed when UV rays strike its provitamin form of vegetal origin (ergosterol), and Vitamin D3 (cholecalciferol), which is produced in animal organisms by irradiation of 7-dehydrocholesterol. Vitamin D3 or cholecalciferol then undergoes a first hydroxylation reaction in various tissues with the formation of 25-hydroxycholecalciferol 25(OH)D3 which passes into the general circulation and binds to a specific transport protein (vitamin D binding protein, or DBP). Once in the kidney, 25(OH)D3 can undergo two different hydroxylation reactions, catalyzed by different hydroxylases (1- and 24-hydroxylases), which give rise, respectively, to 1,25-dihydroxycholecalciferol [1,25(OH)2D3] (or calcitriol), the active component; 24,25-dihydroxycholecalciferol [24,25(OH)2D3], an inactive form.
The metabolically active form of Vitamin D (or calcitriol) is essential for maintaining calcium and phosphorus homeostasis. In fact, it promotes intestinal absorption of calcium and phosphorus, promotes calcium reabsorption at the renal level, and the processes of bone mineralization, i.e. calcium deposition at the level of bone tissue.

Vitamin K2
It catalyzes the carboxylation and therefore the activation of osteocalcin, the protein produced by osteoblasts, essential in the bone formation process, thus improving the density of bone mass.