Name
Tamarine 80 mg/g + 3.9 mg/g jam
Cassia angustifolia + cassia fistula


What it is and what it is used for
Tamarine contains the active ingredients cassia angustifolia and cassia fistula, which have a laxative effect.
Tamarine is indicated for the short-term treatment of occasional constipation.
Contact your doctor if you do not feel better or if you feel worse after 7 days.


What you need to know before taking the medicine
Do not use Tamarine if:
- are allergic to cassia angustifolia, cassia fistula or any of the other ingredients of this medicine (listed in section 6);
- you suffer from Crohn's disease or if you suffer from ulcerative colitis (inflammatory bowel disease);
- she was diagnosed with peritonitis (inflammation of the tissues lining the organs contained in the abdomen);
- has liver disease;
- has abdominal pain, even of unknown origin;
- has episodes of nausea or vomiting;
- has a bowel obstruction;
- has rectal bleeding of unknown origin;
- has or is at risk of perforation of the digestive tract (stomach and intestine);
- have acute diverticulitis (recent-onset inflammation of the diverticula, small balloon-shaped sacs that form on the wall of the intestine);
- have appendicitis (inflammation of a small lump in the intestine located in the lower right part of the abdomen);
- suffers from a serious state of dehydration (excessive loss of water from the body) and has a loss of mineral salts contained in the blood (sodium and potassium);
- if you are pregnant or breast-feeding (see "Fertility, pregnancy and breast-feeding").

Tamarine should not be given to children under 12 years of age.


Warnings and precautions
Talk to your pharmacist before using Tamarine.

Health education notes
First of all, it must be kept in mind that, in most cases, a balanced diet rich in water and fiber (bran, vegetables and fruit) can permanently solve the problem of constipation.
Many people think they are constipated if they are unable to have a bowel movement every day.
This is a misconception because this situation is completely normal for a large number of individuals. Instead, consider that constipation occurs when evacuations are reduced compared to one's personal habits and are associated with the emission of hard stools.
If episodes of constipation occur repeatedly, a doctor should be consulted.
Treatment of chronic or recurrent constipation always requires the intervention of a doctor for diagnosis, prescription of medications and monitoring during treatment.

Consult your doctor :
• if the need for the medicine is due to a sudden change in your bowel habits (frequency and characteristics of bowel movements) that lasts for more than two weeks or when the use of the laxative fails to produce effects;
• if he is elderly or in poor health.

Laxative abuse
Frequent, prolonged or excessive use of laxatives can cause persistent diarrhea with consequent loss of water, mineral salts contained in the blood (especially potassium) and other essential nutrients.
In more serious cases, dehydration (excessive loss of water from the body) or hypokalaemia (decrease in potassium in the blood) may occur, which may cause problems with the heart, nerves and muscles, especially in case of concomitant treatment with cardiac glycosides (medicines used to treat heart problems), diuretics (medicines used to lower blood pressure) or corticosteroids (anti-inflammatories), see "Other medicines and Tamarine".
Laxative abuse can cause dependence (possible need to gradually increase the dose), chronic constipation and intestinal atony (loss of normal intestinal function).


Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Side effects with unknown frequency (frequency cannot be estimated from the available data):
• allergic reactions;
• hyperaldosteronism (increased activity of the adrenal glands which causes water retention, increased blood pressure and weakness), reduction in the amount of calcium, magnesium, sodium and potassium in the blood, dehydration (excessive loss of water from the body), loss of mineral salts contained in the blood;
• hypotension (low blood pressure);
• megacolon (intestinal distension), diarrhea, nausea, abdominal discomfort;
• myopathy (muscle pain);
• kidney problems;
• chromaturia (abnormal coloration of urine);
• fatigue;
• drug tolerance (loss of effectiveness of the medicine).

Following the instructions in the package leaflet reduces the risk of side effects.

Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the national reporting system at: https://www.aifa.gov.it/content/segnalazionireazioni-avverse .
By reporting side effects you can help provide more information on the safety of this medicine.