Name
DOLAUT THROAT 0.25% mouthwash
flurbiprofen


What it is and what it is used for
Dolaut gola contains flurbiprofen which is an anti-inflammatory medicine used for oral cavity conditions.
Dolaut gola is used to treat the symptoms of irritation and inflammation, also associated with pain in the mouth and throat (e.g. gingivitis, stomatitis, pharyngitis), also as a consequence of dental therapies (conservative or extractive).

Talk to your doctor if you do not feel better or if you feel worse after a short time of treatment.


What you need to know before taking the medicine
Do not use Dolaut Throat
- if you are allergic to the active substance or any of the other ingredients of this medicine (listed in section 6),
- if you are allergic to aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs), particularly when the allergy is associated with asthma or urticaria,
- if you are in the last three months of pregnancy (See "Pregnancy and breast-feeding"),
- if you have or have had in the past an injury to your stomach or intestines (peptic ulcer),
- if she is breastfeeding.


Warnings and precautions
Talk to your doctor or pharmacist before using Dolaut gola.
• At the recommended doses, swallowing Dolaut gola does not cause any harm as the quantity ingested is much lower than that of a single dose of the medicine taken systemically (e.g. by mouth).
• If you use Dolaut gola mouthwash, especially for a prolonged period, you may experience sensitization or local irritation phenomena; in such cases, stop the treatment and consult your doctor to have, if necessary, an appropriate therapy.
• If you do not obtain appreciable results after a short period of treatment, consult your doctor.
• If you suffer from kidney, heart or liver failure, use the medicine with caution.
• Do not combine Dolaut gola with other non-steroidal anti-inflammatory drugs (NSAIDs).
• Talk to your doctor or pharmacist if you have an infection – see “Infections” section below.

Infections
Nonsteroidal anti-inflammatory drugs (NSAIDs) may hide signs of infection such as fever and pain. This may delay appropriate treatment of the infection, which may increase the risk of complications. If you take this medicine during an infection and the symptoms of the infection persist or worsen, contact your doctor or pharmacist immediately.


Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
The use of the medicine, especially if prolonged, can give rise to phenomena of sensitization or local irritation; in such cases, interrupt the treatment and the doctor, if necessary, will prescribe an appropriate therapy.
Following the instructions in the package leaflet reduces the risk of side effects.

The following undesirable effects have been reported, particularly after administration of formulations for systemic use, e.g. oral (by mouth):
• alteration of blood cells (thrombocytopenia, aplastic anemia and agranulocytosis)
• allergic reactions, even serious ones (anaphylaxis, angioedema, allergic reaction)
• dizziness
• damage to blood vessels in the brain (cerebrovascular accidents)
• vision problems, inflammation of the nerves in the eye (optic neuritis)
• migraine
• alteration of sensation in the limbs and other parts of the body (paraesthesia)
• depression, confusion, hallucination
• vertigo
• malaise
• fatigue and drowsiness
• Ringing in the ears (tinnitus)
• breathing difficulties due to inflammation (asthma, bronchospasm and dyspnea)
• nausea, vomiting, diarrhoea, passing wind from the anus (flatulence), constipation (constipation), difficulty in digesting (dyspepsia), abdominal pain, blood in the stool (melena), vomiting blood (haematemesis), inflammation of the mouth with lesions that are difficult to heal (ulcerative stomatitis), loss of blood from the stomach and intestines and worsening of inflammation of a part of the intestine called the colon (exacerbation of colitis) and of a disease called Crohn's disease
• inflammation of the stomach (gastritis), lesions, perforations and loss of blood in the stomach and intestines (peptic ulcer, perforation and ulcer haemorrhage)
• skin disorders (rash, pruritus, urticaria, purpura and very rarely bullous dermatoses including Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis and Erythema multiforme)
• kidney damage (including interstitial nephritis and nephrotic syndrome and rare cases of renal failure as seen with other nonsteroidal anti-inflammatory drugs - NSAIDs).

Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the national reporting system at: https://www.aifa.gov.it/content/segnalazionireazioni-avverse .
By reporting side effects you can help provide more information on the safety of this medicine.