Name
VECTRA 3D

Category
Ectoparasiticides for topical use.

Active ingredients
Dinotefuran, pyriproxyfen, permethrin.

Directions
Fleas: Treatment and prevention of flea infestation (Ctenocephalides felis and Ctenocephalides canis). The treatment prevents flea infestation for one month. It also prevents the multiplication of fleas for two months after application by inhibiting the hatching of eggs (ovicidal activity) and by inhibiting the emergence of adults from eggs laid by adult fleas (larvicidal activity). The veterinary medicinal product can be used as part of a treatment strategy for flea allergy dermatitis (FAD). Ticks: The veterinary medicinal product has persistent acaricidal efficacy and repellent action against tick infestations (Rhipicephalus sanguineus and Ixodes ricinus for one month, and Dermacentor reticulatus for up to three weeks). If ticks are present when the veterinary medicinal product is applied, they may not all be killed within the first 48 hours but may die within a week. To remove ticks, the use of a special device for the removal of ticks is recommended. Sandflies, mosquitoes and flies: the treatment provides persistent repellent activity (anti-feeding). Prevents bites of sandflies (Phlebotomus perniciosus), mosquitoes (Culex pipiens, Aedes aegypti) and flies (Stomoxys calcitrans) for one month after application. The treatment also provides persistent insecticidal activity for one month against mosquitoes (Aedes aegypti) and flies (Stomoxys calcitrans).

Dosage
The minimum recommended dose is 6.4 mg dinotefuran/kg body weight, 0.6 mg pyriproxyfen/kg body weight and 46.6 mg permethrin/kg body weight, equivalent to 0.12 ml of the veterinary medicinal product per kg body weight. Use the appropriate pack size based on the body weight of the animal. Care should be taken to apply the veterinary medicinal product only to intact skin. Avoid superficial application to the dog's coat. Treatment schedule: Following a single application, the veterinary medicinal product will prevent infestation for one month. Treatment may be repeated once a month.

Conservation
This veterinary medicinal product does not require any special storage conditions.

Pregnancy and breastfeeding
The safety of the veterinary medicinal product in bitches has not been established during pregnancy and lactation. The use of the veterinary medicinal product in pregnant and lactating bitches or in dogs intended for breeding should be based on a benefit/risk assessment. Laboratory studies, with each of the components, dinotefuran, pyriproxyfen or permethrin, in rats and rabbits have not shown any maternotoxic, teratogenic or foetotoxic effects. Dinotefuran has been shown to cross the blood-mammary barrier and is excreted in milk. N-methylpyrrolidone, an excipient of the veterinary medicinal product, has been shown to be teratogenic in laboratory animals.